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  • 1
    Keywords: Fuzzy sets-Congresses. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (505 pages)
    Edition: 1st ed.
    ISBN: 9783319257839
    Series Statement: Lecture Notes in Computer Science Series ; v.9437
    Language: English
    Note: Intro -- Preface -- Organization -- Contents -- Rough Sets: The Experts Speak -- Decision-Oriented Rough Set Methods -- 1 Introduction -- 2 Decision-Oriented Rough Set Models and Methods -- 3 Concluding Remarks and Future Perspectives -- References -- On Generalized Decision Functions: Reducts, Networks and Ensembles -- 1 Introduction -- 2 Generalized Decision Functions -- 3 Simplified Conditional Independence -- 4 Generalized Decision Measures -- 5 Embedded Decision Reducts -- 6 Ensembles of Complementary Reducts -- 7 Attribute Decomposition Problem -- 8 Heuristics and Boolean Representation -- 9 Conclusions and Future Directions -- References -- Formalization of Medical Diagnostic Rules -- 1 Introduction -- 2 Background: Medical Diagnostic Process -- 2.1 RHINOS -- 2.2 Focusing Mechanism -- 3 Basics of Rule Definitions -- 3.1 Rough Sets -- 3.2 Classification Accuracy and Coverage -- 3.3 Probabilistic Rules -- 4 Formalization of Medical Diagnostic Rules -- 4.1 Deterministic Model -- 4.2 Probabilistic Model -- 5 New Rule Induction Model -- 6 Discussion: What Has Not Been Achieved? -- 7 Conclusion -- References -- Multi-granularity Intelligent Information Processing -- 1 Introduction -- 2 Multi-granularity Rough Set Theory -- 3 Multi-granularity Computing with Words -- 4 Multi-granularity Fuzzy Quotient Space Theory -- 5 Multi-granularity Cloud Model -- 6 Multi-granularity Clustering Based on Density Peaks -- 7 Conclusion -- References -- Granular Structures Induced by Interval Sets and Rough Sets -- 1 Introduction -- 2 Interval Sets -- 2.1 Interval Sets and Interval-Set Algebras -- 2.2 Inclusion Relations in Interval Sets -- 2.3 Granular Structure in Interval Sets -- 3 The Granular Structure Based on Order Relation in Interval Sets -- 3.1 Preference -- 3.2 Interval Set Comparisons. , 4 Granular Structures in Interval Sets from Set-Theoretic Perspectives -- 4.1 Granular Structure for (I(2U),w) -- 4.2 Granular Structure for (I(2U),w+) -- 4.3 Granular Structure for (I(2U),p) -- 4.4 Granular Structure for (I(2U),c) -- 5 Connections of Rough Sets and Interval Sets -- 6 Conclusions -- References -- Generalized Rough Sets -- Empirical Risk Minimization for Variable Consistency Dominance-Based Rough Set Approach -- 1 Introduction -- 2 Variable Consistency Dominance-Based Rough Set Approach -- 3 Empirical Risk Minimization -- 4 Concluding Remarks -- References -- Rough Set Approximations in Multi-scale Interval Information Systems -- 1 Introduction -- 2 Interval Information Systems -- 2.1 Information Systems -- 2.2 Interval Information Systems -- 3 Multi-scale Interval Information Systems -- 3.1 Multi-scale Information Systems -- 3.2 Multi-scale Interval Information Systems -- 4 Rough Set Approximations -- 5 Conclusion -- References -- A New Subsystem-Based Definition of Generalized Rough Set Model -- 1 Introduction -- 2 Preliminaries -- 3 A New Subsystem-Based Definition of Generalized Rough Set Model -- 4 Conclusion -- References -- A Comparison of Two Types of Covering-Based Rough Sets Through the Complement of Coverings -- 1 Introduction -- 2 Preliminaries -- 3 Relationships Between FL, FH and SL, SH Through the Complement of Coverings -- 3.1 Complementary Neighborhood -- 3.2 The Complement of a Covering and Relationships between the Two Types of Covering-Based Rough Sets -- 3.3 Conditions Under Which FH and SH Are Identical -- 4 Extension of a Covering -- 5 Matroidal Approach and the Exact Sets -- 6 Conclusions -- References -- On the Nearness Measures of Near Sets -- 1 Introduction -- 2 Preliminaries -- 3 Nearness Measures -- 4 Strong Nearness Relations -- 5 Concluding Remarks -- References. , Topological Properties for Approximation Operators in Covering Based Rough Sets -- 1 Introduction -- 2 Preliminaries -- 2.1 Pawlak's Rough Set Approximations -- 2.2 Closures -- 2.3 Covering Based Rough Sets -- 2.4 Other Framework of Lower and Upper Approximations -- 2.5 New Framework of Approximation Operators -- 3 Topological Characterization of Upper Approximations -- 4 Algebraic and Topological Properties -- 5 Conclusions -- References -- Rough Sets and Graphs -- Preclusivity and Simple Graphs -- 1 Introduction -- 2 Preliminary Notions -- 2.1 Graphs -- 2.2 Preclusivity Spaces -- 2.3 Formal Concept Analysis -- 3 Simple Graphs as Preclusivity Spaces -- 3.1 Two Basic Cases -- 4 The Cube of Opposition Generated by the Preclusive Relation -- 5 Conclusion -- References -- Preclusivity and Simple Graphs: The n--cycle and n--path Cases -- 1 Introduction -- 2 Preliminary Notions -- 2.1 Graphs -- 2.2 Preclusivity Spaces -- 2.3 Simple Graphs as Preclusivity Spaces -- 3 The Case of Cn -- 4 The Case of Pn -- 5 Conclusion -- References -- Connectedness of Graph and Matroid by Covering-Based Rough Sets -- 1 Introduction -- 2 Basic Definitions -- 2.1 Rough Set -- 2.2 Matroid -- 2.3 Graph -- 3 Covering Induced by Graph -- 4 The Connectedness of Matroid Induced by Covering -- 5 Conclusions -- References -- Controllability in Directed Complex Networks: Granular Computing Perspective -- 1 Introduction -- 2 Definitions -- 2.1 Controllability of Complex Networks Based on the Linear System -- 2.2 Granular Computing -- 3 The Techniques to Enhance Controllability of Directed Complex Networks Based on GrC -- 4 Examples -- 5 Conclusions and Future Work -- References -- Rough and Fuzzy Hybridization -- Dynamic Maintenance of Rough Fuzzy Approximations with the Variation of Objects and Attributes -- 1 Introduction -- 2 Preliminaries. , 3 Matrix Representation of the Lower and Upper Approximations in the FDS -- 4 Dynamically Maintenance of Approximations in the FDS Under the Variation of Attributes and Objects -- 5 An Illustrative Example -- 6 Conclusions -- References -- Semi-Supervised Fuzzy-Rough Feature Selection -- 1 Introduction -- 2 Rough and Fuzzy-Rough Set Theory -- 3 Semi-Supervised Fuzzy-Rough Feature Selection -- 4 Experimental Evaluation -- 4.1 Experimental Setup -- 4.2 Results -- 5 Conclusion -- References -- Modified Generalised Fuzzy Petri Nets for Rule-Based Systems -- 1 Introduction -- 2 Preliminaries -- 2.1 Triangular Norms -- 2.2 Fuzzy Implications -- 3 Generalised Fuzzy Petri Nets -- 4 Modified Generalised Fuzzy Petri Nets -- 5 Example -- 6 Concluding Remarks -- References -- Fuzzy Rough Decision Trees for Multi-label Classification -- 1 Introduction -- 2 Related Works -- 2.1 Multi-label Decision Trees -- 2.2 Multi-label Feature Evaluation with Fuzzy Rough Sets -- 3 Multi-label Fuzzy Rough Decision Trees -- 4 Experiments -- 4.1 A Toy Example -- 4.2 Numerical Experiments -- 4.3 Experiment Results -- 5 Conclusions -- References -- Axiomatic Characterizations of Reflexive and T-Transitive I-Intuitionistic Fuzzy Rough Approximation Operators -- 1 Introduction -- 2 Preliminaries -- 2.1 Intuitionistic Fuzzy Logical Operators -- 2.2 Intuitionistic Fuzzy Sets -- 3 Constructive Definitions of I-Intuitionistic Fuzzy Rough Approximation Operators -- 4 Axioms of I-Intuitionistic Fuzzy Rough Approximation Operators -- 5 Conclusion -- References -- Granular Computing -- Knowledge Supported Refinements for Rough Granular Computing: A Case of Life Insurance Industry -- Abstract -- 1 Introduction -- 2 Preliminary -- 2.1 Rough Set Approach (RSA) and Extended Applications -- 2.2 DEMATEL-Based ANP (DANP) Method -- 3 Research Approach. , 3.1 Dominance-Based Rough Set Approach (DRSA) -- 3.2 DEMATEL-Based ANP Method (DANP) -- 3.3 Suggested Steps for the Proposed Approach -- 4 Empirical Case of Life Insurance Industry in Taiwan -- 4.1 Data -- 4.2 Knowledge-Supported Refinements of Approximation Spaces -- 5 Conclusion and Remarks -- References -- Building Granular Systems - from Concepts to Applications -- 1 Introduction -- 2 Information Granulation -- 3 Models of Granules -- 4 Models of Computing with Granules -- 5 Evaluation of Granular Systems -- 6 Conclusions -- References -- The Rough Granular Approach to Classifier Synthesis by Means of SVM -- 1 Introduction -- 1.1 Motivation -- 1.2 Methodology -- 1.3 Granulation in Rough Mereology -- 1.4 Support Vector Machine Classifier -- 2 Optimized Concept Dependent -Granulation -- 3 Experimental Session -- 3.1 Results of Experiments -- 4 Conclusions -- References -- Data Mining and Machine Learning -- The Boosting and Bootstrap Ensemble for Classifiers Based on Weak Rough Inclusions -- 1 Introduction -- 1.1 Theoretical Background of Our Classifiers -- 2 8_v1.1-8_v1.5 Classifiers -- 3 Classifiers Stabilisation Methods -- 3.1 Bootstrap Ensembles -- 3.2 Boosting Based on Arcing -- 3.3 Boosting Based on Ada-Boost with Monte Carlo Split -- 4 Experimental Session -- 4.1 The Results of Experiments -- 5 Conclusions -- References -- Extraction of Off-Line Handwritten Characters Based on a Soft K-Segments for Principal Curves -- 1 Introduction -- 2 A Soft K-segments Algorithm for Principal Curves -- 2.1 Principal Curves -- 2.2 A Soft K-segments Algorithm for Principal Curves -- 3 Structural Extraction of Off-Line Handwritten Characters Based on a Soft K-segments Principal Curves -- 4 Conclusions -- References -- A Knowledge Acquisition Model Based on Formal Concept Analysis in Complex Information Systems -- 1 Introduction -- 2 Basic Notions of FCA. , 3 Classification Analysis in Domain of Attribute Based On GrC.
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  • 2
    Publication Date: 2017-08-25
    Description: Long noncoding RNA XIST expedites metastasis and modulates epithelial–mesenchymal transition in colorectal cancer Cell Death and Disease 8, e3011 (August 2017). doi:10.1038/cddis.2017.421 Authors: Dong-liang Chen, Le-zong Chen, Yun-xin Lu, Dong-sheng Zhang, Zhao-lei Zeng, Zhi-zhong Pan, Peng Huang, Feng-hua Wang, Yu-hong Li, Huai-qiang Ju & Rui-hua Xu
    Electronic ISSN: 2041-4889
    Topics: Biology , Medicine
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  • 3
    Publication Date: 2018-08-21
    Description: The significance of peri-transplantation minimal residual disease assessed by multiparameter flow cytometry on outcomes for adult AML patients receiving haploidentical allografts The significance of peri-transplantation minimal residual disease assessed by multiparameter flow cytometry on outcomes for adult AML patients receiving haploidentical allografts, Published online: 20 August 2018; doi:10.1038/s41409-018-0300-8 The significance of peri-transplantation minimal residual disease assessed by multiparameter flow cytometry on outcomes for adult AML patients receiving haploidentical allografts
    Print ISSN: 0268-3369
    Electronic ISSN: 1476-5365
    Topics: Medicine
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  • 4
    Publication Date: 2018-12-06
    Description: Chemotherapy plus DLI for relapse after haploidentical HSCT: the biological characteristics of relapse influences clinical outcomes of acute leukemia patients Chemotherapy plus DLI for relapse after haploidentical HSCT: the biological characteristics of relapse influences clinical outcomes of acute leukemia patients, Published online: 05 December 2018; doi:10.1038/s41409-018-0406-z Chemotherapy plus DLI for relapse after haploidentical HSCT: the biological characteristics of relapse influences clinical outcomes of acute leukemia patients
    Print ISSN: 0268-3369
    Electronic ISSN: 1476-5365
    Topics: Medicine
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  • 5
    Publication Date: 2012-12-18
    Description: Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration Journal of Investigative Dermatology 133, 42 (January 2013). doi:10.1038/jid.2012.235 Authors: Yu-Hong Li, Kun Zhang, Ke Yang, Ji-Xing Ye, Yi-Zhan Xing, Hai-Ying Guo, Fang Deng, Xiao-Hua Lian & Tian Yang
    Print ISSN: 0022-202X
    Electronic ISSN: 1523-1747
    Topics: Medicine
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  • 6
    Publication Date: 2017-04-21
    Description: Urinary and Fecal Metabonomics Study of the Protective Effect of Chaihu-Shu-Gan-San on Antibiotic-Induced Gut Microbiota Dysbiosis in Rats Scientific Reports, Published online: 20 April 2017; doi:10.1038/srep46551
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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  • 7
    Publication Date: 2017-05-09
    Description: The antifungal effects and mechanical properties of silver bromide/cationic polymer nano-composite-modified Poly-methyl methacrylate-based dental resin Scientific Reports, Published online: 8 May 2017; doi:10.1038/s41598-017-01686-4
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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  • 8
    Publication Date: 2016-11-10
    Description: Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment Nature 539, 7628 (2016). doi:10.1038/nature20131 Authors: Lei Dong, Wen-Mei Yu, Hong Zheng, Mignon L. Loh, Silvia T. Bunting, Melinda Pauly, Gang Huang, Muxiang Zhou, Hal E. Broxmeyer, David T. Scadden & Cheng-Kui Qu Germline activating mutations of the protein tyrosine phosphatase SHP2 (encoded by PTPN11), a positive regulator of the RAS signalling pathway, are found in 50% of patients with Noonan syndrome. These patients have an increased risk of developing leukaemia, especially juvenile myelomonocytic leukaemia (JMML), a childhood myeloproliferative neoplasm (MPN). Previous studies have demonstrated that mutations in Ptpn11 induce a JMML-like MPN through cell-autonomous mechanisms that are dependent on Shp2 catalytic activity. However, the effect of these mutations in the bone marrow microenvironment remains unclear. Here we report that Ptpn11 activating mutations in the mouse bone marrow microenvironment promote the development and progression of MPN through profound detrimental effects on haematopoietic stem cells (HSCs). Ptpn11 mutations in mesenchymal stem/progenitor cells and osteoprogenitors, but not in differentiated osteoblasts or endothelial cells, cause excessive production of the CC chemokine CCL3 (also known as MIP-1α), which recruits monocytes to the area in which HSCs also reside. Consequently, HSCs are hyperactivated by interleukin-1β and possibly other proinflammatory cytokines produced by monocytes, leading to exacerbated MPN and to donor-cell-derived MPN following stem cell transplantation. Remarkably, administration of CCL3 receptor antagonists effectively reverses MPN development induced by the Ptpn11-mutated bone marrow microenvironment. This study reveals the critical contribution of Ptpn11 mutations in the bone marrow microenvironment to leukaemogenesis and identifies CCL3 as a potential therapeutic target for controlling leukaemic progression in Noonan syndrome and for improving stem cell transplantation therapy in Noonan-syndrome-associated leukaemias.
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2015-10-08
    Description: Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast Scientific Reports, Published online: 7 October 2015; doi:10.1038/srep14707
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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  • 10
    Publication Date: 2014-06-04
    Description: The use of combination drugs is considered to be a promising strategy to control complex diseases such as ischemic stroke. The detection of metabolites has been used as a versatile tool to reveal the potential mechanism of diverse diseases. In this study, the levels of 12 endogenous AAs were simultaneously determined quantitatively in the MCAO rat brain using RRLC-QQQ method. Seven AAs were chosen as the potential biomarkers, and using PLS-DA analysis, the effects of the new combination drug YQJD, which is composed of ginsenosides, berberine, and jasminoidin, on those 7 AAs were evaluated. Four AAs, glutamic acid, homocysteine, methionine, and tryptophan, which changed significantly in the YQJD-treated groups compared to the vehicle groups (P 〈 0.05), were identified and designated as the AAs to use to further explore the synergism of YQJD. The result of a PCA showed that the combination of these three drugs exhibits the strongest synergistic effect compared to other combination groups and that ginsenosides might play a pivotal role, especially when combined with jasminoidin. We successfully explored the synergetic mechanism of multi-component and provided a new method for evaluating the integrated effects of combination drugs in the treatment of complex diseases. Scientific Reports 4 doi: 10.1038/srep05149
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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