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  • Cambridge University Press (CUP)  (1)
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  • Cambridge University Press (CUP)  (1)
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    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2022
    In:  Twin Research and Human Genetics Vol. 25, No. 1 ( 2022-02), p. 50-55
    In: Twin Research and Human Genetics, Cambridge University Press (CUP), Vol. 25, No. 1 ( 2022-02), p. 50-55
    Abstract: The aim of this study was to determine the pregnancy loss rate of amniocentesis with double-needle insertions in twin pregnancies. This was a retrospective study of twin pregnancies who underwent amniocentesis with double-needle insertion between 2010 and 2019 at a single center. The pregnancy loss rates were recorded as single or double fetal loss before 24 weeks’ gestation and within 4 weeks after the procedure. Risk factors for pregnancy loss after amniocentesis were also assessed. A total of 678 twin pregnancies with amniocentesis were finally included. The pregnancy loss rates before 24 weeks’ gestation and within 4 weeks after the procedure were 0.9% and 1.9%, respectively. Only one fetal loss was presumed to be a direct result of the procedure. All other cases were complicated by structural or chromosomal anomalies. Twin pregnancies with abnormal ultrasound findings had a significantly higher rate of pregnancy loss with a relative risk of 4.81 (95% CI [1.03, 22.2]). Our study showed a low pregnancy loss rate after amniocentesis in twin pregnancies with double-needle insertions technique of sampling, which can help decision making in prenatal screening and diagnosis for twin pregnancies.
    Type of Medium: Online Resource
    ISSN: 1832-4274 , 1839-2628
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2022
    detail.hit.zdb_id: 2184274-7
    SSG: 12
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