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  • 1
    Online Resource
    Online Resource
    Impact of Postdischarge Surveillance on Surgical Site Infection Rates for Several Surgical Procedures Results From the Nosocomial Surveillance Network in The Netherlands
    Cambridge University Press (CUP) ; 2006
    In:  Infection Control & Hospital Epidemiology Vol. 27, No. 8 ( 2006-08), p. 809-816
    Details
    In: Infection Control & Hospital Epidemiology, Cambridge University Press (CUP), Vol. 27, No. 8 ( 2006-08), p. 809-816
    Abstract: To compare the number of surgical site infections (SSIs) registered after hospital discharge with respect to various surgical procedures and to identify the procedures for which postdischarge surveillance (PDS) is most important. Design. Prospective SSI surveillance with voluntary PDS. Recommended methods for PDS in the Dutch national nosocomial surveillance network are addition of a special registration card to the outpatient medical record, on which the surgeon notes clinical symptoms and whether a patient developed an SSI according to the definitions; an alternative method is examination of the outpatient medical record. Setting. Hospitals participating in the Dutch national nosocomial surveillance network between 1996 and 2004. Results. We collected data on 131,798 surgical procedures performed in 64 of the 98 Dutch hospitals. PDS was performed according to one of the recommended methods for 31,134 operations (24%) and according to another active method for 32,589 operations (25%), and passive PDS was performed for 68,075 operations (52%). Relatively more SSIs were recorded after discharge for cases in which PDS was performed according to a recommended method (43%), compared with cases in which another active PDS method was used (30%) and cases in which passive PDS was used (25%). The highest rate of SSI after discharge was found for appendectomy (79% of operations), followed by knee prosthesis surgery (64%), mastectomy (61%), femoropopliteal or femorotibial bypass (53%), and abdominal hysterectomy (53%). Conclusions. For certain surgical procedures, most SSIs develop after discharge. SSI rates will be underestimated if no PDS is performed. We believe we have found a feasible and sensitive method for PDS that, if patients routinely return to the hospital for a postdischarge follow-up visit, might be suitable for use internationally.
    Type of Medium: Online Resource
    ISSN: 0899-823X , 1559-6834
    URL: Article
    DOI: 10.1017/S0195941700045112
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2006
    detail.hit.zdb_id: 2106319-9
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  • 2
    Online Resource
    Online Resource
    Effect of parasitism on plasma sex-specific proteins in Cyphocarax gilbert (Teleost, Curimatidae)
    Cambridge University Press (CUP) ; 2005
    In:  Parasitology Vol. 130, No. 6 ( 2005-06), p. 653-659
    Details
    In: Parasitology, Cambridge University Press (CUP), Vol. 130, No. 6 ( 2005-06), p. 653-659
    Abstract: Cyphocarax gilbert (Szidat, L., 1948) is a fish commonly found in coastal drainage of eastern Brazil. This fish is sometimes caught with signs of infection by the crustacean Riggia paranensis , a haematophagous parasite. A remarkable feature of infected fish is that they lack gonads. In this paper we have analysed the frequency of parasitism, the gonadal development of non-infected fish and the profile of plasma proteins in both infected and non-infected specimens. Two reproductive periods/year were observed, beginning in February and August. On average, 40% of fish were infected, in the Itabapoana River (Brazil). Sex-specific proteins were identified by electrophoresis. SDS-PAGE analysis demonstrated that a 143 kDa female-specific glycolipoprotein (FSP) is a calcium-binding phosphoprotein. FSP was isolated through ultracentrifugation and SDS-PAGE analysis showed that the native protein is composed of three polypeptides of 143, 100 and 70 kDa. Both FSP and a 33 kDa male-specific protein (MSP) are absent from infected fish plasma. FSP levels in female plasma changes with the developmental stage of gonads. Altogether these data suggest that the FSP corresponds to fish vitellogenin. Furthermore, the absence of the above-mentioned proteins in infected fish suggests that R. paranensis might interfere with the regular hormonal process of fish vitellogenesis.
    Type of Medium: Online Resource
    ISSN: 0031-1820 , 1469-8161
    URL: Article
    DOI: 10.1017/S0031182004007140
    RVK:
    WA 15000
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2005
    detail.hit.zdb_id: 1491287-9
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Psychometric Evaluation of the German Version of the Centre for Epidemiological Studies Depression Scale for Children (CES-DC)
    Cambridge University Press (CUP) ; 2009
    In:  European Psychiatry Vol. 24, No. S1 ( 2009-01), p. 1-1
    Details
    In: European Psychiatry, Cambridge University Press (CUP), Vol. 24, No. S1 ( 2009-01), p. 1-1
    Abstract: To examine the psychometric properties and test-theoretical quality of the German version of the Centre for Epidemiological Studies Depression Scale for Children (CES-DC), a 20 items comprising screening instrument which measures the frequency of parent- and self-reported depressive symptoms in children and adolescents. Methods: Using a population-based, representative sample of N=2.863 7 to 17 year old German children and adolescents, factorial validity by means of linear structural modelling, cross-sectional coefficients of reliability, inter-rater agreement and normative scores are determined. Results: In a population-based German sample, the 4-factor version of the CES-DC following Radloff (1977) is considered to have good factorial validity and stability across age and informant version. The main problems of the questionnaire are the high difficulties of the items, strong floor effects of the scales and low cross-sectional reliability, which is just acceptable for screening purposes. The low inter-rater agreement indicate that parental assessment can replace self-assessment only to a limited degree. Conclusion: The strengths and weaknesses of the CES-DC are discussed taking into consideration previous data and comparable tests. Particular advantages are the existence of the parent report form and the adult version, as well as its multifactorial structure. Parental assessment should be supplemented by self-report data whenever possible.
    Type of Medium: Online Resource
    ISSN: 0924-9338 , 1778-3585
    URL: Article
    DOI: 10.1016/S0924-9338(09)70844-2
    RVK:
    XA 10000
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2009
    detail.hit.zdb_id: 2005377-0
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  • 4
    Online Resource
    Online Resource
    Impact of Postdischarge Surveillance on Surgical Site Infection Rates for Several Surgical Procedures Results From the Nosocomial Surveillance Network in The Netherlands
    Cambridge University Press (CUP) ; 2006
    In:  Infection Control & Hospital Epidemiology Vol. 27, No. 8 ( 2006-08), p. 809-816
    Details
    In: Infection Control & Hospital Epidemiology, Cambridge University Press (CUP), Vol. 27, No. 8 ( 2006-08), p. 809-816
    Abstract: To compare the number of surgical site infections (SSIs) registered after hospital discharge with respect to various surgical procedures and to identify the procedures for which postdischarge surveillance (PDS) is most important. Design. Prospective SSI surveillance with voluntary PDS. Recommended methods for PDS in the Dutch national nosocomial surveillance network are addition of a special registration card to the outpatient medical record, on which the surgeon notes clinical symptoms and whether a patient developed an SSI according to the definitions; an alternative method is examination of the outpatient medical record. Setting. Hospitals participating in the Dutch national nosocomial surveillance network between 1996 and 2004. Results. We collected data on 131,798 surgical procedures performed in 64 of the 98 Dutch hospitals. PDS was performed according to one of the recommended methods for 31,134 operations (24%) and according to another active method for 32,589 operations (25%), and passive PDS was performed for 68,075 operations (52%). Relatively more SSIs were recorded after discharge for cases in which PDS was performed according to a recommended method (43%), compared with cases in which another active PDS method was used (30%) and cases in which passive PDS was used (25%). The highest rate of SSI after discharge was found for appendectomy (79% of operations), followed by knee prosthesis surgery (64%), mastectomy (61%), femoropopliteal or femorotibial bypass (53%), and abdominal hysterectomy (53%). Conclusions. For certain surgical procedures, most SSIs develop after discharge. SSI rates will be underestimated if no PDS is performed. We believe we have found a feasible and sensitive method for PDS that, if patients routinely return to the hospital for a postdischarge follow-up visit, might be suitable for use internationally.
    Type of Medium: Online Resource
    ISSN: 0899-823X , 1559-6834
    URL: Article
    DOI: 10.1086/506403
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2006
    detail.hit.zdb_id: 2106319-9
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  • 5
    Online Resource
    Online Resource
    Hospital-Related Determinants For Surgical-Site Infection Following Hip Arthroplasty
    Cambridge University Press (CUP) ; 2005
    In:  Infection Control & Hospital Epidemiology Vol. 26, No. 5 ( 2005-05), p. 435-441
    Details
    In: Infection Control & Hospital Epidemiology, Cambridge University Press (CUP), Vol. 26, No. 5 ( 2005-05), p. 435-441
    Abstract: To determine hospital-related risk factors for surgical-site infection (SSI) following hip arthroplasty. Design: Prospective, multicenter cohort study based on surveillance data and data collected through a structured telephone interview. With the use of multilevel logistic regression, the independent effect of hospital-related characteristics on SSI was assessed. Setting: Thirty-six acute care hospitals in the Dutch surveillance network for nosocomial infections (PREZIES), from 1996 to 2000. Patients: Thirteen thousand six hundred eighty patients who underwent total or partial hip arthroplasty. Results: A high annual volume of operations was associated with a reduced risk of SSI (risk-adjusted risk ratio [RR] per 50 extra operations, 0.85; 95% confidence interval [CI 95 ], 0.74–0.97). With each extra full-time–equivalent infection control staff member per 250 beds available for prevention of SSI, the risk for SSI was decreased (RR, 0.48; CI 95 , 0.16–1.44), although the decrease was not statistically significant. Hospital size, teaching status, university affiliation, and number of surgeons and their years of experience showed no important association with the risk of SSI. Conclusion: Undergoing surgery in a hospital with a low volume of operations increases a patient's risk of SSI.
    Type of Medium: Online Resource
    ISSN: 0899-823X , 1559-6834
    URL: Article
    DOI: 10.1086/502564
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2005
    detail.hit.zdb_id: 2106319-9
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  • 6
    Online Resource
    Online Resource
    Expansion of spatial and host range of Puumala virus in Sweden: an increasing threat for humans?
    Cambridge University Press (CUP) ; 2017
    In:  Epidemiology and Infection Vol. 145, No. 8 ( 2017-06), p. 1642-1648
    Details
    In: Epidemiology and Infection, Cambridge University Press (CUP), Vol. 145, No. 8 ( 2017-06), p. 1642-1648
    Abstract: Hantaviruses are globally distributed and cause severe human disease. Puumala hantavirus (PUUV) is the most common species in Northern Europe, and the only hantavirus confirmed to circulate in Sweden, restricted to the northern regions of the country. In this study, we aimed to further add to the natural ecology of PUUV in Sweden by investigating prevalence, and spatial and host species infection patterns. Specifically, we wanted to ascertain whether PUUV was present in the natural reservoir, the bank vole ( Myodes glareolus ) further south than Dalälven river, in south-central Sweden, and whether PUUV can be detected in other rodent species in addition to the natural reservoir. In total, 559 animals were collected at Grimsö (59°43′N; 15°28′E), Sala (59°55′N; 16°36′E) and Bogesund (59°24′N; 18°14′E) in south-central Sweden between May 2013 and November 2014. PUUV ELISA-reactive antibodies were found both in 2013 (22/295) and in 2014 (18/264), and nine samples were confirmed as PUUV-specific by focus reduction neutralization test. Most of the PUUV-specific samples were from the natural host, the bank vole, but also from other rodent hosts, indicating viral spill-over. Finally, we showed that PUUV is present in more highly populated central Sweden.
    Type of Medium: Online Resource
    ISSN: 0950-2688 , 1469-4409
    URL: Article
    DOI: 10.1017/S0950268817000346
    RVK:
    XA 41125
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2017
    detail.hit.zdb_id: 1470211-3
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  • 7
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    Online Resource
    Improved Risk Adjustment for Comparison of Surgical Site Infection Rates
    Cambridge University Press (CUP) ; 2006
    In:  Infection Control & Hospital Epidemiology Vol. 27, No. 12 ( 2006-12), p. 1330-1339
    Details
    In: Infection Control & Hospital Epidemiology, Cambridge University Press (CUP), Vol. 27, No. 12 ( 2006-12), p. 1330-1339
    Abstract: To develop prognostic models for improved risk adjustment in surgical site infection surveillance for 5 surgical procedures and to compare these models with the National Nosocomial Infection Surveillance system (NNIS) risk index. Design. In a multicenter cohort study, prospective assessment of surgical site infection and risk factors was performed from 1996 to 2000. In addition, risk factors abstracted from patient files, available in a national medical register, were used. The c-index was used to measure the ability of procedure-specific logistic regression models to predict surgical site infection and to compare these models with models based on the NNIS risk index. A c-index of 0.5 indicates no predictive power, and 1.0 indicates perfect predictive power. Setting. Sixty-two acute care hospitals in the Dutch national surveillance network for nosocomial infections. Participants. Patients who underwent 1 of 5 procedures for which the predictive ability of the NNIS risk index was moderate: reconstruction of the aorta ( n = 875), femoropopliteal or femorotibial bypass ( n = 641), colectomy ( n = 1,142), primarytotal hip prosthesis ( n = 13,770), and cesarean section ( n = 2,962). Results. The predictive power of the new model versus the NNIS index was 0.75 versus 0.62 for reconstruction of the aorta ( P 〈 .01), 0.78 versus 0.58 for femoropopliteal or femorotibial bypass ( P 〈 .001), 0.69 versus 0.62 for colectomy ( P 〈 .001), 0.64 versus 0.56 for primary total hip prosthesis arthroplasty ( P 〈 .001), and 0.70 versus 0.54 for cesarean section ( P 〈 .001). Conclusion. Data available from hospital information systems can be used to develop models that are better at predicting the risk of surgical site infection than the NNIS risk index. Additional data collection may be indicated for certain procedures–for example, total hip prosthesis arthroplasty.
    Type of Medium: Online Resource
    ISSN: 0899-823X , 1559-6834
    URL: Article
    DOI: 10.1086/509841
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2006
    detail.hit.zdb_id: 2106319-9
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  • 8
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    Online Resource
    Internal and External Validation of a Computer-Assisted Surveillance System for Hospital-Acquired Infections in a 754-Bed General Hospital in the Netherlands
    Cambridge University Press (CUP) ; 2016
    In:  Infection Control & Hospital Epidemiology Vol. 37, No. 11 ( 2016-11), p. 1355-1360
    Details
    In: Infection Control & Hospital Epidemiology, Cambridge University Press (CUP), Vol. 37, No. 11 ( 2016-11), p. 1355-1360
    Abstract: To evaluate a computer-assisted point-prevalence survey (CAPPS) for hospital-acquired infections (HAIs). DESIGN Validation cohort. SETTING A 754-bed teaching hospital in the Netherlands. METHODS For the internal validation of a CAPPS for HAIs, 2,526 patients were included. All patient records were retrospectively reviewed in depth by 2 infection control practitioners (ICPs) to determine which patients had suffered an HAI. Preventie van Ziekenhuisinfecties door Surveillance (PREZIES) criteria were used. Following this internal validation, 13 consecutive CAPPS were performed in a prospective study from January to March 2013 to determine weekly, monthly, and quarterly HAI point prevalence. Finally, a CAPPS was externally validated by PREZIES (Rijksinstituut voor Volksgezondheid en Milieu [RIVM], Bilthoven, Netherlands). In all evaluations, discrepancies were resolved by consensus. RESULTS In our series of CAPPS, 83% of the patients were automatically excluded from detailed review by the ICP. The sensitivity of the method was 91%. The time spent per hospital-wide CAPPS was ~3 hours. External validation showed a negative predictive value of 99.1% for CAPPS. CONCLUSIONS CAPPS proved to be a sensitive, accurate, and efficient method to determine serial weekly point-prevalence HAI rates in our hospital. Infect Control Hosp Epidemiol 2016;1–6
    Type of Medium: Online Resource
    ISSN: 0899-823X , 1559-6834
    URL: Article
    DOI: 10.1017/ice.2016.159
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2016
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