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  • Cambridge University Press (CUP)  (71)
  • 1
    In: Bulletin of Entomological Research, Cambridge University Press (CUP), Vol. 66, No. 3 ( 1976-09), p. 469-480
    Abstract: A technique, based on the release and recapture of marked females, was used to measure the mating competitiveness of sterile males of Culex pipiens fatigans Wied. in villages in Delhi Union Territory, India. Experiments were carried out with chemosterilised and cytoplasmically incompatible translocated (IS-31B) males simultaneously with prolonged release trials with these two types of male. The fertile males in the tests were the indigenous population and the females used were in most cases of wild origin. With each type of male, one test was conducted with a moderate (ca. 13:1) ratio of released to wild males and the other tests used high (ca. 40:1) ratios. The estimated mean mating competitiveness of IS-31B males was somewhat higher than that of chemosterilised males, but the difference was found to be non-significant using a specially devised method of testing statistical significance. In the four experiments 77–94% of the egg rafts laid by recaptured females were sterile, indicating that both types of sterile male were sufficiently competitive to induce a high level of egg sterility in an isolated wild population.
    Type of Medium: Online Resource
    ISSN: 0007-4853 , 1475-2670
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1976
    detail.hit.zdb_id: 1496538-0
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  • 2
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1964
    In:  Bulletin of Entomological Research Vol. 55, No. 2 ( 1964-08), p. 249-270
    In: Bulletin of Entomological Research, Cambridge University Press (CUP), Vol. 55, No. 2 ( 1964-08), p. 249-270
    Abstract: Investigations of the natural history of the virus of Kyasanur Forest disease since its discovery during 1957 in Shimoga District, Mysore State, south India have concentrated much attention on ticks of the genus Haemaphysalis in the region, as virus has repeatedly been isolated from them. Keys are provided for larvae, nymphs and adults of both sexes of the 14 species of Haemaphysalis that have been taken in the area, with supplementary comments on six other species of the genus recorded, or likely to occur, elsewhere in south India. Illustrations are given showing the characters of the larvae and nymphs that are used in the keys.
    Type of Medium: Online Resource
    ISSN: 0007-4853 , 1475-2670
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1964
    detail.hit.zdb_id: 1496538-0
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  • 3
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1968
    In:  Parasitology Vol. 58, No. 2 ( 1968-05), p. 461-463
    In: Parasitology, Cambridge University Press (CUP), Vol. 58, No. 2 ( 1968-05), p. 461-463
    Abstract: Arthur & Chaudhuri (1965) have reviewed the literature dealing with the taxonomic status of Nosomma monstrosum (Nuttall & Warburton, 1908). They have also redescribed the adults and have given the host and geographical distribution of this species. There have, however, been no descriptions or records of immature stages of this species. They are described and illustrated here from laboratory-reared and field-collected material. The parent females of the laboratory-reared material were compared with the female specimen in the Indian Museum collection, reg. no. 2172/17, on which the description of the female was based (Warburton, 1918).
    Type of Medium: Online Resource
    ISSN: 0031-1820 , 1469-8161
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1968
    detail.hit.zdb_id: 1491287-9
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  • 4
    In: Experimental Agriculture, Cambridge University Press (CUP), Vol. 49, No. 2 ( 2013-04), p. 161-178
    Abstract: Long-term tillage and fertilizer experiments were conducted in rice in kharif followed by lentil in dry subhumid Inceptisols at Varanasi and Faizabad; horse gram at Phulbani and linseed at Ranchi in moist subhumid Alfisols in rabi during 2001 to 2010. The study was conducted to assess the effect of conventional tillage (CT), low tillage + interculture (LT1) and low tillage + herbicide (LT2) together with 100% N (organic) (F1), 50% N (organic) + 50% N (inorganic) (F2) and 100% N (inorganic) (F3) on productivity, profitability, rainwater and energy use efficiencies. The results at Varanasi revealed that CT was superior with mean yield of 2389 kg ha −1 , while F1 was superior with 2378 kg ha −1 in rice. At Faizabad, CT was superior with mean rice yield of 1851 kg ha −1 and lentil yield of 977 kg ha −1 , while F1 was superior with 1704 and 993 kg ha −1 of rice and lentil, respectively. At Phulbani, F2 was superior with rice yield of 1170 kg ha −1 . At Ranchi, F2 with rice yield of 986 kg ha −1 and F3 with linseed yield of 224 kg ha −1 were superior. The regression model of crop seasonal rainfall and yield deviations indicated an increasing trend in rice yield over mean (positive deviation) with increase in rainfall at all locations; while a decreasing trend (negative deviation) was found for lentil at Faizabad, horse gram at Phulbani and linseed at Ranchi. Based on economic analysis, CTF1 at Varanasi and Faizabad, CTF2 at Phulbani and LT2F2 at Ranchi were superior.
    Type of Medium: Online Resource
    ISSN: 0014-4797 , 1469-4441
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2013
    detail.hit.zdb_id: 2016166-9
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  • 5
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1999
    In:  Experimental Agriculture Vol. 35, No. 2 ( 1999-04), p. 141-152
    In: Experimental Agriculture, Cambridge University Press (CUP), Vol. 35, No. 2 ( 1999-04), p. 141-152
    Abstract: Floodwater was characterized through field surveys over three years in rainfed lowland and deepwater rice areas of Eastern India. Measurements focused on dissolved O 2 and CO 2 , pH and irradiance during flash floods in rice fields. Over locations and time, dissolved O 2 concentrations ranged from zero to 0.28 mol m −3 (0–1.1 times air-saturated water at 30 °C) while dissolved CO 2 ranged from 0.28 to 1.96 mol m −3 (31–217 times air-saturated water). Floodwater pH varied from 6.6 to 9.7. Irradiance decreased with depth in the water profile to an extent depending on turbidity. Turbidity varied greatly over locations and time. The significance of these measurements in assessing rice submergence tolerance is discussed.
    Type of Medium: Online Resource
    ISSN: 0014-4797 , 1469-4441
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1999
    detail.hit.zdb_id: 2016166-9
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  • 6
    In: Geological Magazine, Cambridge University Press (CUP), Vol. 157, No. 6 ( 2020-06), p. 989-1000
    Abstract: The eastern Arabian Sea is influenced by both the advection of upwelled water from the western Arabian Sea and winter convective mixing. Therefore, sediments collected from the eastern Arabian Sea can help to understand the long-term seasonal hydrographic changes. We used the planktonic foraminifera census and stable isotopic ratio (δ 18 O) from sediments drilled during the International Ocean Discovery Program Expedition 355 to reconstruct surface hydrographic changes in the eastern Arabian Sea during the last 350 kyr. The increased abundance of Globigerina bulloides suggests enhanced advection of upwelled water during the latter half of MIS7 and the beginning of MIS6, as a result of a strengthened summer monsoon. A large drop in upwelling and/or advection of upwelled water from the western Arabian Sea is inferred during the subsequent interval of MIS6, based on the rare presence of G. bulloides . The comparable relative abundance of Neogloboquadrina dutertrei , G. bulloides and Globigerinoides ruber suggests that during the early part of MIS5, hydrographic conditions were similar to today. The upwelling decreased and winter convection increased with the progress of the glacial interval. A good coherence between planktonic foraminiferal assemblage-based monsoon stacks from both the eastern and western Arabian Sea suggests a coeval response of the entire northern Arabian Sea to the glacial–interglacial changes. The glacial–interglacial difference in δ 18 O sw-ivc was at a maximum with 4–5 psu change in salinity during Termination 2 and 3, and a minimum during Termination 4. The significantly reduced regional contribution to the glacial–interglacial change in δ 18 O sw-ivc during Termination 4 suggests a lesser change in the monsoon.
    Type of Medium: Online Resource
    ISSN: 0016-7568 , 1469-5081
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2020
    detail.hit.zdb_id: 956405-6
    detail.hit.zdb_id: 1479206-0
    SSG: 13
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  • 7
    In: Experimental Agriculture, Cambridge University Press (CUP), Vol. 48, No. 1 ( 2012-01), p. 1-20
    Abstract: Long-term field experiments were conducted at Agra, Solapur and Hisar from 2000 to 2008 to identify efficient tillage and nutrient management practices and to develop predictive models that would describe the relationship between crop yields and monthly rainfall for rainfed pearl millet grown on arid and semi-arid Inceptisol, Vertisol and Aridisol soils. Nine treatments comprising a factorial combination of three tillage practices, viz., conventional tillage (CT), low tillage + interculture (LT1) and low tillage + herbicide (LT2) and three fertilizer treatments viz., 100% N from an organic source (F1), 50% organic N + 50% inorganic N (F2) and 100% inorganic N (F3) were tested in a split-plot design at the three locations. Studies revealed that tillage and fertilizer treatments, and their interactions, significantly influenced pearl millet grain yields at the three locations. Prediction models describing the relation between grain yield and monthly rainfall indicated that rainfall occurring in June, July and August at Agra; June and July at Solapur; and June and August at Hisar significantly influenced pearl millet grain yield attained by different treatments. The R 2 values of the model ranged from 0.64 to 0.81 at Agra; 0.63 to 0.92 at Solapur, and 0.75 to 0.89 at Hisar. When averaged over all the treatment combinations, mean pearl millet grain yields varied from 1590 to 1744 kg ha −1 at Agra; 1424 to 1786 kg ha −1 at Solapur; and 1675 to 1766 kg ha −1 at Hisar while their corresponding sustainability yield indice (SYI) varied from 35.4 to 42.2%, 19.9 to 45.6% and 64.1 to 68.3%, respectively. At Agra (Inceptisol), CTF3 resulted in significantly higher mean net returns (Rs 11 439 ha −1 ), benefit-cost ratio (2.33), rainwater use efficiency (RWUE) (3.52 kg ha −1 mm −1 ) and the second best SYI (39.9%). At Solapur (Vertisol), the LT1F3 resulted in significantly higher net returns (Rs 12 818 ha −1 ), benefit-cost ratio (3.52), RWUE (3.89 kg ha −1 mm −1 ) and the fourth best SYI (42.6%). At Hisar (Aridisol), the LT 1 F 3 treatment gave higher net returns (Rs 3866 ha −1 ), benefit-cost ratio (1.26), RWUE (5.05 kg ha −1 mm −1 ) and the fourth best SYI (67.8%). These treatment combinations can be recommended for their respective locations to achieve maximum RWUE, productivity and profitability.
    Type of Medium: Online Resource
    ISSN: 0014-4797 , 1469-4441
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2012
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  • 8
    In: Parasitology, Cambridge University Press (CUP), Vol. 145, No. 3 ( 2018-03), p. 292-306
    Abstract: Immunoactivation depends upon the antigen potential to modulate T-cell repertoires. The present study has enumerated the effect of 61 kDa recombinant Leishmania donovani co-factor-independent phosphoglycerate mutase (r Ld -iPGAM) on mononuclear cells of healthy and treated visceral leishmaniasis subjects as well as on THP-1 cell line. r Ld -iPGAM stimulation induced higher expression of interleukin-1 β (IL-1 β ) in the phagocytic cell, its receptor and CD69 on T-cell subsets. These cellular activations resulted in upregulation of host-protective cytokines IL-2, IL-12, IL-17, tumour necrosis factor- α and interferon- γ , and downregulation of IL-4, IL-10 and tumour growth factor- β . This immune polarization was also evidenced by upregulation of nuclear factor- κ light-chain enhancer of activated B cells p50 and regulated expression of suppressor of mother against decapentaplegic protein-4. r Ld -iPGAM stimulation also promoted lymphocyte proliferation and boosted the leishmaniacidal activity of macrophages by upregulating reactive oxygen species. It also induced 1·8-fold higher release of nitric oxide (NO) by promoting the transcription of inducible nitric oxide synthase gene. Besides, in silico analysis suggested the presence of major histocompatibility complex class I and II restricted epitopes, which can proficiently trigger CD8 + and CD4 + cells, respectively. This study reports r Ld -iPGAM as an effective immunoprophylactic agent, which can be used in future vaccine design.
    Type of Medium: Online Resource
    ISSN: 0031-1820 , 1469-8161
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2018
    detail.hit.zdb_id: 1491287-9
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  • 9
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2016
    In:  Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques Vol. 43, No. S4 ( 2016-10), p. S2-S2
    In: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, Cambridge University Press (CUP), Vol. 43, No. S4 ( 2016-10), p. S2-S2
    Abstract: Brain Metastases (BM) represent a leading cause of cancer mortality. While metastatic lesions contain subclones derived from their primary lesion, their functional characterization has been limited by a paucity of preclinical models accurately recapitulating the stages of metastasis. This work describes the isolation of a unique subset of metastatic stem-like cells from primary human patient samples of BM, termed brain metastasis initiating cells (BMICs). Utilizing these BMICs we have established a novel patient-derived xenograft (PDX) model of BM that recapitulates the entire metastatic cascade, from primary tumor initiation to micro-metastasis and macro-metastasis formation in the brain. We then comprehensively interrogated human BM to identify genetic regulators of BMICs using in vitro and in vivo RNA interference screens, and validated hits using both our novel PDX model as well as primary clinical BM specimens. We identified SPOCK1 and TWIST2 as novel BMIC regulators, where in our model SPOCK1 regulated BMIC self-renewal and tumor initiation, and TWIST2 specifically regulated cell migration from lung to brain. A prospective cohort of primary lung cancer specimens was used to establish that SPOCK1 and TWIST2 were only expressed in patients who ultimately developed BM, thus establishing both clinical and functional utility for these gene products. This work offers the first comprehensive preclinical model of human brain metastasis for further characterization of therapeutic targets, identification of predictive biomarkers, and subsequent prophylactic treatment of patients most likely to develop BM. By blocking this process, metastatic lung cancer would effectively become a localized, more manageable disease.
    Type of Medium: Online Resource
    ISSN: 0317-1671 , 2057-0155
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2016
    detail.hit.zdb_id: 2577275-2
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  • 10
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2017
    In:  Parasitology Vol. 144, No. 10 ( 2017-09), p. 1412-1416
    In: Parasitology, Cambridge University Press (CUP), Vol. 144, No. 10 ( 2017-09), p. 1412-1416
    Abstract: Demodex canis infestation in dogs remains one of the main challenges in veterinary dermatology. The exact pathogenesis of canine demodicosis is unknown but an aberration in immune status is considered very significant. No studies have underpinned the nexus between induction of demodicosis and neural immunosuppressive pathways so far. We have evaluated the involvement of cholinergic pathways in association with cytokines regulation as an insight into the immuno-pathogenesis of canine demodicosis in the present study. Remarkable elevations in circulatory immunosuppressive cytokine interleukin-10 and cholinesterase activity were observed in dogs with demodicosis. Simultaneously, remarkable reduction in circulatory pro-inflammatory cytokine tumour necrosis factor-alpha level was observed in dogs with demodicosis. Findings of the present study evidently suggest that Demodex mites might be affecting the cholinergic pathways to induce immunosuppression in their host and then proliferate incessantly in skin microenvironment to cause demodicosis.
    Type of Medium: Online Resource
    ISSN: 0031-1820 , 1469-8161
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2017
    detail.hit.zdb_id: 1491287-9
    SSG: 12
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