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  • Cambridge University Press (CUP)  (67)
  • 1
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2019
    In:  Zygote Vol. 27, No. 4 ( 2019-08), p. 219-224
    In: Zygote, Cambridge University Press (CUP), Vol. 27, No. 4 ( 2019-08), p. 219-224
    Abstract: This is a retrospective study over a 5-year period. In total, 3139 embryos were individually cryopreserved (Cryotop®) and warmed using the Kitazato vitrification/warming kit. They were classified into three categories based on their expansion degree. Transfer, implantation and pregnancy rates were assessed for each embryo category and compared using SPSS (Statistical Package for the Social Sciences) software. In total, 1139 couples enrolled in infertility treatment programme benefitted from embryo vitrification at day 5. After warming, embryos belonging to the three categories showed similar success rates. Although there was a trend towards better outcomes when grade 3 embryos were transferred, the differences did not reach statistical significance: implantation rates ( n fetal sac/ n embryo transferred) grade 1: 21.9%, grade 2: 22.7% and grade 3: 30.3% (=0.19). Pregnancy rate ( n clinical pregnancy/ n transfer) (21.9%, 22.7%, 30.3%, respectively; P =0.11). Miscarriage rate was not statistically different in the three categories (14.5%, 20.4%, 20%, respectively, P =0.51). Our overall results show that it is worth vitrifying slow kinetics embryos as they provide a non-negligible chance to give rise to a pregnancy.
    Type of Medium: Online Resource
    ISSN: 0967-1994 , 1469-8730
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2019
    detail.hit.zdb_id: 1483381-5
    SSG: 12
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  • 2
    In: European Psychiatry, Cambridge University Press (CUP), Vol. 24, No. 2 ( 2009-03), p. 98-104
    Abstract: There is wide acknowledgement that apathy is an important behavioural syndrome in Alzheimer’s disease and in various neuropsychiatric disorders. In light of recent research and the renewed interest in the correlates and impacts of apathy, and in its treatments, it is important to develop criteria for apathy that will be widely accepted, have clear operational steps, and that will be easily applied in practice and research settings. Meeting these needs is the focus of the task force work reported here. The task force includes members of the Association Française de Psychiatrie Biologique, the European Psychiatric Association, the European Alzheimer’s Disease Consortium and experts from Europe, Australia and North America. An advanced draft was discussed at the consensus meeting (during the EPA conference in April 7th 2008) and a final agreement reached concerning operational definitions and hierarchy of the criteria. Apathy is defined as a disorder of motivation that persists over time and should meet the following requirements. Firstly, the core feature of apathy, diminished motivation, must be present for at least four weeks; secondly two of the three dimensions of apathy (reduced goal-directed behaviour, goal-directed cognitive activity, and emotions) must also be present; thirdly there should be identifiable functional impairments attributable to the apathy. Finally, exclusion criteria are specified to exclude symptoms and states that mimic apathy.
    Type of Medium: Online Resource
    ISSN: 0924-9338 , 1778-3585
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2009
    detail.hit.zdb_id: 2005377-0
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  • 3
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2004
    In:  European psychiatry (Ed. Española) Vol. 11, No. 5 ( 2004-06), p. 297-302
    In: European psychiatry (Ed. Española), Cambridge University Press (CUP), Vol. 11, No. 5 ( 2004-06), p. 297-302
    Abstract: La dimensión bipolar de matutinidad-vespertinidad se refiere a los momentos preferidos del día para llevar a cabo diversas actividades (es decir, la fase del reloj circadiano). Está validada desde un punto de vista biológico, se asocia al menos con un gen y es heredable por medio de un mecanismo epistásico. Se ha utilizado como variable próxima para estudiar las relaciones entre el sistema circadiano, la per-sonalidad y las manifestaciones psicopatológicas: hay una correlación entre la orientación vespertina y la depresión, la extraversión y, pro-bablemente, la impulsividad. Además, hay una posible relación con el temperamento en nifios, segiin teorizaron Thomas y Chess. En este artículo, desarrollamos la hipótesis de que los sujetos impulsivos puntúan bajo en matutinidad realizando un análisis factorial de la Esca- la Compuesta de Matutinidad, el Inventario del Temperamento y el Carácter de Cloninger y el Inventario de Ansiedad como Rasgo de Spielberger en una muestra de 129 varones. Probablemente, los resultados se pueden extender a mujeres. La matutinidad correlaciona negativamente con la búsqueda de novedad (que incluye una faceta de impulsividad), correlaciona positivamente con la persistencia y es independiente de las dimensiones de carácter y la ansiedad como rasgo. La investigación futura puede centrarse en la participación del sistema circadiano en estas dimensiones y facetas de la personalidad, y los beneficios de afiadir manipulaciones cronoterapéuticas en el tratamiento de los trastornos de la personalidad.
    Type of Medium: Online Resource
    ISSN: 1134-0665 , 2695-5466
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2004
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  • 4
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1994
    In:  European Psychiatry Vol. 9, No. 6 ( 1994), p. 304-306
    In: European Psychiatry, Cambridge University Press (CUP), Vol. 9, No. 6 ( 1994), p. 304-306
    Abstract: A study was conducted on a group of 73 patients suffering from major depressive disorder (DSMIII) compared with 120 normal subjects using a subscale of physical pleasure (Fawcett Clark pleasure capacity scale-physical pleasure, FCPCS-PP). The major depressives were significantly more anhedonic than the normals and the distribution of the FCPCS-PP scores in these subjects was unimodal.
    Type of Medium: Online Resource
    ISSN: 0924-9338 , 1778-3585
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1994
    detail.hit.zdb_id: 2005377-0
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  • 5
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2000
    In:  European Psychiatry Vol. 15, No. 4 ( 2000-6), p. 278-281
    In: European Psychiatry, Cambridge University Press (CUP), Vol. 15, No. 4 ( 2000-6), p. 278-281
    Type of Medium: Online Resource
    ISSN: 0924-9338
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2000
    detail.hit.zdb_id: 2005377-0
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  • 6
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1996
    In:  European Psychiatry Vol. 11 ( 1996-1), p. 303s-
    In: European Psychiatry, Cambridge University Press (CUP), Vol. 11 ( 1996-1), p. 303s-
    Type of Medium: Online Resource
    ISSN: 0924-9338
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1996
    detail.hit.zdb_id: 2005377-0
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  • 7
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1999
    In:  European Psychiatry Vol. 14, No. 5 ( 1999-09), p. 284-290
    In: European Psychiatry, Cambridge University Press (CUP), Vol. 14, No. 5 ( 1999-09), p. 284-290
    Abstract: The objective of this study was to provide a reliable instrument to measure morningness for upcoming studies in French samples, using the Composite Scale of Morningness (CSM), which has been translated into French. Nursing students ( n = 356) completed the questionnaire between February and March 1997. The total score obtained was independent of age and gender, and normally distributed. The reliability was high (Cronbach's α = 0.85), and factorial analysis confirmed the unidimensionality of the scale. Evening-type subjects are thought to score under 31, and morning-type subjects are thought to score above 44. As an external validation, morningness was associated, on weekdays and weekends, with early rising times and bedtimes and early peak times of physical and mental performance. In conclusion, we found that the English and the French versions of the Composite Scale of Morningness gave identical results. The scale is reliable and can be used for French-speaking adult samples. Nevertheless, normative data and other external validity criteria are needed.
    Type of Medium: Online Resource
    ISSN: 0924-9338 , 1778-3585
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1999
    detail.hit.zdb_id: 2005377-0
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  • 8
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2016
    In:  Epidemiology and Infection Vol. 144, No. 10 ( 2016-07), p. 2176-2183
    In: Epidemiology and Infection, Cambridge University Press (CUP), Vol. 144, No. 10 ( 2016-07), p. 2176-2183
    Abstract: Clostridium difficile diarrhoea is an urgent threat to patients, but little is known about the role of antibiotic administration that starts in emergency department observation units (EDOUs). We studied risk factors for antibiotic-associated diarrhoea (AAD) and C. difficile infection (CDI) in EDOU patients. This prospective cohort study enrolled adult patients discharged after EDOU antibiotic treatment between January 2013 and 2014. We obtained medical histories, EDOU treatment and occurrence of AAD and CDI over 28 days after discharge. We enrolled and followed 275 patients treated with antibiotics in the EDOU. We found that 52 (18·6%) developed AAD and four (1·5%) had CDI. Patients treated with vancomycin [relative risk (RR) 0·52, 95% confidence interval (CI) 0·3–0·9] were less likely to develop AAD. History of developing diarrhoea with antibiotics (RR 3·11, 95% CI 1·92–5·03) and currently failing antibiotics (RR 1·90, 95% CI 1·14–3·16) were also predictors of AAD. Patients with CDI were likely to be treated with clindamycin. In conclusion, AAD occurred in almost 20% of EDOU patients with risk factors including a previous history of diarrhoea with antibiotics and prior antibiotic therapy, while the risk of AAD was lower in patients receiving treatment regimens utilizing intravenous vancomycin.
    Type of Medium: Online Resource
    ISSN: 0950-2688 , 1469-4409
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2016
    detail.hit.zdb_id: 1470211-3
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  • 9
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2001
    In:  European psychiatry (Ed. Española) Vol. 8, No. 1 ( 2001-02), p. 27-37
    In: European psychiatry (Ed. Española), Cambridge University Press (CUP), Vol. 8, No. 1 ( 2001-02), p. 27-37
    Abstract: La desinhibición y la irritabilidad, definidas como la pérdida de control del comportamiento y la emotión, son frecuentes en los ancianos. La hipótesis de trabajo para este estudio era que estos trastornos se asocian con una alteratión cognitiva de los procesos de control que se manifiesta como un comportamiento no habitual a causa de la disfunción de un componente ejecutivo general conocido como Sistema Atentivo Supervisor (SAS). Métodos . Se seleccionó un total de 28 sujetos ancianos con deterioro cognitivo leve y se los dividió en dos grupos utilizando el Inventario Neuropsiquiátrico. Catorce sujetos se asignaron al grupo desinhibido y 14 sujetos emparejados en cuanto a la edad, el sexo y el nivel educativo formaron un grupo de control sin desinhibición. La batería neuropsicológica incluía las pruebas siguientes: Mini Examen del Estado Mental, el Test de Nombres de Boston, el Test de Fichas, el Test de Trazado y la prueba de fluidez verbal. Se diseñaron específicamente dos tareas para someter a un esfuerzo al SAS: 1) Una tarea verbal específica de ordenación de oraciones en la que los sujetos tenían que utilizar razona-miento secuencial con material verbal. Cada secuencia de prueba consístia en una serie de palabras que se mostraban en orden alterado. La construcción de algunas secuencias se tenía que hacer utilizando asociaciones habituales familiares (condiciones válidas). Por contraste, otras secuencias requerían hacer caso omiso de la selección de tales asociaciones, que eran inapropiadas dentro del contexto general de la tarea (condiciones inválidas). 2) Utilizando el test de ejecución continua, se evaluaron cuatro aspectós: atención sostenida, atención selectiva, preparatión de la atención y atención supresiva. Resultados . Las únicas dife-rencias de grupo en los resultados de las pruebas neuropsicológicas fueron las siguientes: 1) La tarea de ordenación de oraciones. En comparación con el grupo de control, el grupo desinhibido mostraba deficiencia en las condiciones inválidas y la diferencia calculada entre el número de respuestas correctas en las condiciones inválidas menos el número correspondiente en las condiciones válidas era significativamente más alto, y 2) el test de ejecución continua. Los sujetos desinhibidos tenían un número significativamente más bajo de éxitos, exclusivamente en el paradigma de “atención supresiva”. Estos resultados indican que la función del sistema supervisor de los sujetos con desinhibición está deteriorada.
    Type of Medium: Online Resource
    ISSN: 1134-0665 , 2695-5466
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2001
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  • 10
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 1984
    In:  Advances in Applied Probability Vol. 16, No. 04 ( 1984-12), p. 887-905
    In: Advances in Applied Probability, Cambridge University Press (CUP), Vol. 16, No. 04 ( 1984-12), p. 887-905
    Abstract: We consider a single-server queueing system in which a customer gives up whenever his waiting time is larger than a random threshold, his patience time. In the case of a GI/GI/ 1 queue with i.i.d. patience times, we establish the extensions of the classical GI/GI/ 1 formulae concerning the stability condition and the relation between actual and virtual waiting-time distribution functions. We also prove that these last two distribution functions coincide in the case of a Poisson input process and determine their common law.
    Type of Medium: Online Resource
    ISSN: 0001-8678 , 1475-6064
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1984
    detail.hit.zdb_id: 1474602-5
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