GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Cambridge University Press (CUP)  (3)
  • 1
    Online Resource
    Online Resource
    The effects of atomoxetine on emotional control in adults with ADHD: An integrated analysis of multicenter studies
    Cambridge University Press (CUP) ; 2015
    In:  European Psychiatry Vol. 30, No. 4 ( 2015-06), p. 511-520
    Details
    In: European Psychiatry, Cambridge University Press (CUP), Vol. 30, No. 4 ( 2015-06), p. 511-520
    Abstract: To investigate the effects of atomoxetine on emotional control in adults with ADHD. Methods: We performed an integrated analysis using individual patient data pooled from three Eli Lilly-sponsored studies. An integrated analysis can be viewed as a meta-analysis of individual patient-level data, rather than study-level summary data. Results: Two populations were identified: a large sample of patients with pre-treatment baseline data (the “overall population”; n = 2846); and a subset of these patients with placebo-controlled efficacy data from baseline to 10 or 12 weeks after initiating treatment (the “placebo-controlled population”; n = 829). At baseline, in the overall population, ∼50% of ADHD patients had BRIEF-AS (Behavior Rating Inventory of Executive Function-Adult Version Self-Report) Emotional control subscores between 21 and 30, compared with ∼10% of normative subjects in the BRIEF-A manual. At endpoint, in the placebo-controlled population, atomoxetine led to a small (effect size 0.19) but significant ( P = 0.013) treatment effect for emotional control. The effect size was 0.32 in patients with BRIEF-AS Emotional control scores 〉 20 at baseline. Improvements in emotional control correlated with improvements in the core ADHD symptoms and quality-of-life. Discussion: As deficient emotional control is associated with impaired social, educational and occupational functioning over and above that explained by core ADHD symptoms alone, improvements in emotional control may be clinically relevant. Conclusion: At baseline, adults with ADHD were more likely to have impaired emotional control than normative subjects. In the adult ADHD patients, atomoxetine treatment was associated with improvements in emotional control, as well as in core ADHD symptoms and quality-of-life.
    Type of Medium: Online Resource
    ISSN: 0924-9338 , 1778-3585
    URL: Article
    DOI: 10.1016/j.eurpsy.2014.12.002
    RVK:
    XA 10000
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2015
    detail.hit.zdb_id: 2005377-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Towards a Quaternary Time Scale
    Cambridge University Press (CUP) ; 1980
    In:  Quaternary Research Vol. 13, No. 3 ( 1980-05), p. 277-302
    Details
    In: Quaternary Research, Cambridge University Press (CUP), Vol. 13, No. 3 ( 1980-05), p. 277-302
    Abstract: Nine first-appearance datums (FADs), twenty-three last-appearance datums (LADs), and three other micropaleontological datums are related to the magnetic-reversal, oxygen-isotope, and calcite-dissolution/coarse-fraction time scales to provide a preliminary basis for subdivision of the Quaternary in deep-sea sediments. The magnetic-reversal, oxygen-isotope, and calcite-dissolution/coarse-fraction scales have been correlated by determination on the same core materials, and absolute dates applied by 40 K/ 40 Ar or 14 C dating of materials in known positions on one or another of these scales. FADS and LADs have been determined in cores for which either a magnetic-reversal, oxygen-isotope, or calcite-dissolution/coarse-fraction scale has also been available. Altogether 3 FADs and 5 LADs based on diatoms, 4 FADs and 5 LADs based on calcareous nannoplankton, 1 FAD and 8 LADs based on radiolarians, 1 FAD and 5 LADs based on planktonic foraminifers, 2 acme datums, and 1 ratio reversal datum have been determined, and absolute dates inferred by interpolation from known dates on the reference time scales. Some of the FADs and LADs apply or are synchronous only over limited areas of the oceans; others appear to be synchronous throughout the oceans. The base of the Quaternary is set at the top of the Olduvai event at 1.7 my. Four FADs, twelve LADs, two acme datums, and one ratio reversal datum occur above the base of the Quaternary at an average rate of about 1 per 100,000 yr. Five FADs and twelve LADs are recognized in the 0.8-my interval between the top of the Olduvai event and the Gauss/Matuyama Boundary at 2.5 my at an average incidence of about 1 per 50,000 yr.
    Type of Medium: Online Resource
    ISSN: 0033-5894 , 1096-0287
    URL: Article
    DOI: 10.1016/0033-5894(80)90058-7
    RVK:
    RA 1000
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1980
    detail.hit.zdb_id: 1471589-2
    detail.hit.zdb_id: 205711-6
    SSG: 13
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Evidence for punctuated gradualism in the Late Neogene Globorotalia tumida lineage of planktonic foraminifera
    Cambridge University Press (CUP) ; 1983
    In:  Paleobiology Vol. 9, No. 4 ( 1983), p. 377-389
    Details
    In: Paleobiology, Cambridge University Press (CUP), Vol. 9, No. 4 ( 1983), p. 377-389
    Abstract: The warm-water planktonic foraminiferal Globorotalia tumida lineage has been studied in a 10-Myr-long stratigraphic sequence (Late Miocene through Recent) from the Indian Ocean to determine long-term evolutionary patterns through the lineage's history, and particularly to study in great detail the evolutionary transition from G. plesiotumida to G. tumida across the Miocene/Pliocene boundary. Sampling resolution was very good, between 5 × 10 3 and 15 × 10 3 yr across the Miocene/Pliocene boundary and about 2 × 10 5 yr otherwise. The test shape was analyzed in edge view, permitting determinations of variation in inflation and elongation of the test. Shape was analyzed quantitatively using eigenshape analysis. This method represents the greatest proportion of variation observed among a collection of shapes by the least number of different shapes. The Late Miocene (10.4-5.6 Myr B.P.) populations exhibited only minor fluctuations in shape that did not result in any net phyletic change. This period of stasis was followed by an 0.6-Myr-long period (between 5.6 and 5.0 Myr B.P.) of gradual transformation of the Late Miocene morphotype (G. plesiotumida) into the Early Pliocene morphotype (G. tumida). The populations were again more or less in stasis in the Pliocene and Pleistocene (5.0 Myr to the present day), so that no major modifications of the newly evolved Early Pliocene morphotype occurred during these 5 Myr. Thus it would appear that the G. tumida lineage, while remaining in relative stasis over a considerable part of its total duration underwent periodic, relatively rapid, morphologic change that did not lead to lineage branching. This pattern does not conform to the gradualistic model of evolution, because that would assume gradual changes throughout the history of the lineage. It also does not conform to the punctuational model, because (1) there was no speciation (lineage branching) in this lineage and (2) the transition was not rapid enough ( 〈 1% of the descendant species' duration according to definition). For this evolutionary modality we propose the term “punctuated gradualism” and suggest that this may be a common norm for evolution—at least within the planktonic foraminifera.
    Type of Medium: Online Resource
    ISSN: 0094-8373 , 1938-5331
    URL: Article
    DOI: 10.1017/S0094837300007843
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 1983
    detail.hit.zdb_id: 2052186-8
    SSG: 12
    SSG: 13
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...