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  • PANGAEA  (148)
  • Blackwell Science Ltd  (1)
  • Copernicus Publications (EGU)  (1)
  • Frontiers  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 88 (2004), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effect of anoxia on Na+/H+ exchange activity was examined in acutely isolated adult rat hippocampal CA1 neurons loaded with the H+-sensitive fluorophore, BCECF. Five-minute anoxia imposed under nominally HCO3–/CO2-free conditions induced a fall in pHi, the magnitude of which was smaller following prolonged exposure to medium in which N-methyl-d-glucamine (NMDG+) was employed as an extracellular Na+ (Na+o) substitute. Also consistent with the possibility that Na+/H+ exchange becomes inhibited soon after the induction of anoxia, rates of Na+o-dependent pHi recovery from internal acid loads imposed during anoxia were slowed, compared to rates of Na+o-dependent pHi recovery observed prior to anoxia. At the time at which rates of pHi recovery were reduced during anoxia, cellular adenosine triphosphate (ATP) levels had fallen to 35% of preanoxic levels, suggesting that ATP depletion might contribute to the observed inhibition of Na+/H+ exchange. In support, incubation of neurons with 2-deoxyglucose and antimycin A under normoxic conditions induced a fall in cellular ATP levels that was also associated with reduced Na+o-dependent rates of pHi recovery from imposed acid loads; conversely, pre-treatment with 10 mm creatine attenuated the effects of anoxia to reduce both ATP levels and Na+o-dependent rates of pHi recovery from internal acid loads. Taken together, the results are consistent with the possibility that functional Na+/H+ exchange activity in adult rat CA1 neurons declines soon after the onset of anoxia, possibly as a result of anoxia-induced falls in intracellular ATP.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2022-01-31
    Description: Considerable advances in the global ocean observing system over the last two decades offers an opportunity to provide more quantitative information on changes in heat and freshwater storage. Variations in these storage terms can arise through internal variability and also the response of the ocean to anthropogenic climate change. Disentangling these competing influences on the regional patterns of change and elucidating their governing processes remains an outstanding scientific challenge. This challenge is compounded by instrumental and sampling uncertainties. The combined use of ocean observations and model simulations is the most viable method to assess the forced signal from noise and ascertain the primary drivers of variability and change. Moreover, this approach offers the potential for improved seasonal-to-decadal predictions and the possibility to develop powerful multi-variate constraints on climate model future projections. Regional heat storage changes dominate the steric contribution to sea level rise over most of the ocean and are vital to understanding both global and regional heat budgets. Variations in regional freshwater storage are particularly relevant to our understanding of changes in the hydrological cycle and can potentially be used to verify local ocean mass addition from terrestrial and cryospheric systems associated with contemporary sea level rise. This White Paper will examine the ability of the current ocean observing system to quantify changes in regional heat and freshwater storage. In particular we will seek to answer the question: What time and space scales are currently resolved in different regions of the global oceans? In light of some of the key scientific questions, we will discuss the requirements for measurement accuracy, sampling, and coverage as well as the synergies that can be leveraged by more comprehensively analysing the multi-variable arrays provided by the integrated observing system.
    Type: Article , PeerReviewed
    Format: text
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  • 3
    Publication Date: 2024-02-07
    Description: The Earth climate system is out of energy balance, and heat has accumulated continuously over the past decades, warming the ocean, the land, the cryosphere, and the atmosphere. According to the Sixth Assessment Report by Working Group I of the Intergovernmental Panel on Climate Change, this planetary warming over multiple decades is human-driven and results in unprecedented and committed changes to the Earth system, with adverse impacts for ecosystems and human systems. The Earth heat inventory provides a measure of the Earth energy imbalance (EEI) and allows for quantifying how much heat has accumulated in the Earth system, as well as where the heat is stored. Here we show that the Earth system has continued to accumulate heat, with 381±61 ZJ accumulated from 1971 to 2020. This is equivalent to a heating rate (i.e., the EEI) of 0.48±0.1 W m−2. The majority, about 89 %, of this heat is stored in the ocean, followed by about 6 % on land, 1 % in the atmosphere, and about 4 % available for melting the cryosphere. Over the most recent period (2006–2020), the EEI amounts to 0.76±0.2 W m−2. The Earth energy imbalance is the most fundamental global climate indicator that the scientific community and the public can use as the measure of how well the world is doing in the task of bringing anthropogenic climate change under control. Moreover, this indicator is highly complementary to other established ones like global mean surface temperature as it represents a robust measure of the rate of climate change and its future commitment. We call for an implementation of the Earth energy imbalance into the Paris Agreement's Global Stocktake based on best available science. The Earth heat inventory in this study, updated from von Schuckmann et al. (2020), is underpinned by worldwide multidisciplinary collaboration and demonstrates the critical importance of concerted international efforts for climate change monitoring and community-based recommendations and we also call for urgently needed actions for enabling continuity, archiving, rescuing, and calibrating efforts to assure improved and long-term monitoring capacity of the global climate observing system. The data for the Earth heat inventory are publicly available, and more details are provided in Table 4.
    Type: Article , PeerReviewed
    Format: text
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  • 4
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    PANGAEA
    In:  EPIC3WOCE., Bremerhaven, PANGAEA
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: PANGAEA Documentation , notRev
    Format: application/pdf
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  • 5
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    PANGAEA
    In:  Division of Fisheries and Oceanography, Australia
    Publication Date: 2023-02-24
    Keywords: 09FA1089_1; 09FA1089_1-track; ALTITUDE; CT; DATE/TIME; Franklin; LATITUDE; LONGITUDE; Temperature, water; Thermosalinograph; TSG; Underway cruise track measurements; WOCE; World Ocean Circulation Experiment
    Type: Dataset
    Format: text/tab-separated-values, 6332 data points
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  • 6
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    PANGAEA
    In:  Division of Fisheries and Oceanography, Australia
    Publication Date: 2023-02-24
    Keywords: 09FA0793; 09FA0793-track; ALTITUDE; CT; DATE/TIME; Franklin; LATITUDE; LONGITUDE; Quality code; Temperature, water; Thermosalinograph; TSG; Underway cruise track measurements; WOCE; World Ocean Circulation Experiment
    Type: Dataset
    Format: text/tab-separated-values, 7477 data points
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  • 7
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    PANGAEA
    In:  Division of Fisheries and Oceanography, Australia
    Publication Date: 2023-02-24
    Keywords: 09FA0792; 09FA0792-track; ALTITUDE; Calculated; Course; CT; DATE/TIME; Franklin; Humidity, relative; LATITUDE; LONGITUDE; Speed, velocity; Temperature, air; Temperature, water; Thermometer; Thermosalinograph; TSG; Underway cruise track measurements; Wind direction; Wind speed; WOCE; World Ocean Circulation Experiment
    Type: Dataset
    Format: text/tab-separated-values, 30565 data points
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  • 8
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    PANGAEA
    In:  Division of Fisheries and Oceanography, Australia
    Publication Date: 2023-02-24
    Keywords: 09FA1089_2; 09FA1089_2-track; ALTITUDE; CT; DATE/TIME; Franklin; LATITUDE; LONGITUDE; Quality code; Temperature, water; Thermosalinograph; TSG; Underway cruise track measurements; WOCE; World Ocean Circulation Experiment
    Type: Dataset
    Format: text/tab-separated-values, 4854 data points
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  • 9
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    PANGAEA
    In:  Division of Fisheries and Oceanography, Australia
    Publication Date: 2023-02-24
    Keywords: 09FA1091_1; 09FA1091_1-track; ALTITUDE; Calculated; Course; CT; DATE/TIME; Franklin; Humidity, relative; LATITUDE; LONGITUDE; Quality code; Speed, velocity; Temperature, air; Temperature, water; Thermometer; Thermosalinograph; TSG; Underway cruise track measurements; Wind direction; Wind speed; WOCE; World Ocean Circulation Experiment
    Type: Dataset
    Format: text/tab-separated-values, 56302 data points
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  • 10
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    PANGAEA
    In:  Division of Fisheries and Oceanography, Australia
    Publication Date: 2023-02-24
    Keywords: 09FA0394; 09FA0394-track; ALTITUDE; BARO; Barometer; Calculated; Course; CT; DATE/TIME; Franklin; Humidity, relative; LATITUDE; LONGITUDE; Pressure, atmospheric; Speed, velocity; Temperature, air; Temperature, water; Thermometer; Thermosalinograph; TSG; Underway cruise track measurements; Wind direction; Wind speed; WOCE; World Ocean Circulation Experiment
    Type: Dataset
    Format: text/tab-separated-values, 53400 data points
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