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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Grass and forage science 52 (1997), S. 0 
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: To investigate the effect of sward height on liveweight change in goats grazing grass/white clover swards, an experiment was conducted from mid-August to mid-November with groups of non-lactating female cashmere goats that continuously grazed perennial ryegrass (Lolium perenne)/white clover (Trifolium repens) swards. Three replicated different sward height treatments — 10–8 cm (high), 7–5 cm (medium) and 5–3 cm (low) — were used to examine the effects on the competitive ability of grass and clover components within the sward canopy and their effect on liveweight. The pasture after grazing by goats had relatively higher ryegrass leaf (+0·26, high; +0·32, medium; and +0·18, low) and lower dead ryegrass proportions (−0·28, high; −0·23, medium; and −0·18, low) than at the beginning of the experiment, whereas the white clover fraction in the sward remained constant (+0·04, high; −0·02, medium; and +0·03, low). Higher proportions of the white clover leaf lamina and petiole were found near the top of the sward canopy and were negatively correlated with the rate of liveweight gain by goats (P 〈 0·05). Goats gained 50·2 g Live weight (LW) d−1 on the tallest treatment (high) but lost 0·01 and 42·3 g LW d−1 on the medium and low sward height treatments respectively (s.e.d. 13·21, P 〈 0·001). Liveweight changes that occurred between sampling periods were also correlated (R2= 0·858, P 〈 0·001) with changes in the mean sward height and proportion of white clover lamina-petiole at the sward surface in relation to the proportion found within the whole sward. These results suggest that goat liveweight gains would be increased if another species was introduced to reduce the white clover proportion in the surface horizon.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 33 (1995), S. 0 
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 52 (1997), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Moneo I, Audicana MT, Alday E, Curiel G, del Pozo MD, García M. Periodate treatment of Anisakis simplex allergens.Anaphylactic reactions after parasitized fish consumption are mediated by an IgE response. However, positive skin tests and specific IgE can also be found in many asymptomatic subjects who recognize a single medium mol.-wt. antigen by IgE immunoblot. The study aimed to find out whether this unspecificity was due to the carbohydrate moieties of parasite antigens. Sixty-two patients with suspected parasite allergy, 51 blood donors, 18 bakers, and 38 atopic patients were studied by blotting. Parasite proteins were treated with periodate. Several selected sera were inhibited with a crude wheat extract and fungal amylase. Twelve patients ‘19%’, eight donors ‘16%’, six bakers ‘33%’, and one atopic patient ‘3%’ recognized a single mediummol.-wt. band in blotting and should be considered false-positive. This band was periodate-sensitive, but specific IgE to this allergen could not be inhibited by a wheat extract nor by fungal amylase and was clinically irrelevant. Diagnosis of Anisakis simplex hypersensitivity by skin tests and/ or specific IgE values should always be confirmed by specific IgE immunoblotting in order to detect the presence of clinically unrelated antibodies directed to periodate-sensitive allergens. These allergens are probably not a carbohydrate moiety of a parasite glycoprotein.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 58 (1986), S. 1449-1451 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 59 (2004), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Vav1, the 95-kDa protein encoded by the vav1 proto-oncogene, is expressed exclusively in haematopoietic cells, where it becomes phosphorylated on tyrosine residues in response to antigen receptor ligation. Vav1 was found to act as a Rac1-specific guanine nucleotide exchange factor and to activate c-Jun N-terminal kinase (JNK1) in vitro and in ectopic expression systems using non-haematopoietic cells. Here, we studied the role of Vav1 in JNK1 activation in T cells versus non-haematopoietic cells. Vav1 overexpression activated JNK1 in COS7 and 293T cells but not in Jurkat T lymphocytes. In contrast, constitutively activated Rac1 efficiently stimulated JNK1 in both cell types under the same conditions. Vav1 did function in T cells because it clearly stimulated the activity of a nuclear factor of activated T-cell reporter plasmid in the same cells. Moreover, Vav1 induction of JNK1 in T cells required coexpression with calcineurin. This cooperation was cell type specific because it was not observed in COS7 or 293T cells. In contrast, Vav1 did not cooperate with calcineurin to activate either extracellular signal-regulated kinase 2 or p38. These findings demonstrate that Vav1 alone is a poor activator of the JNK1 pathway in T cells and emphasize the importance of studying the physiological functions of Vav1 in haematopoietic cells.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: An experiment was conducted to assess the effects of grazing a perennial ryegrass (Lolium perenne)/ white clover (Trifolium repens) sward by sheep or goats on sward composition and structure and on subsequent diet selection, herbage intake and liveweight gain by weaned lambs. From mid-May to late July (phase 1), ewes with twin lambs or yearling Scottish Cashmere goats grazed continuously swards maintained at 4- or 8-cm sward surface height. From mid-August to the end of September (phase 2), weaned lambs continuously grazed the same swards maintained at 4 cm (treatment 4–4) or at 8 cm (treatment 8–8) or which had been allowed to increase from 4 cm to 8 cm (treatment 4–8). By the end of phase 1, swards grazed by goats had higher proportions of white clover in the whole sward (0.377 vs. 0.181; s.e.d 0.0382; P〈 0.001) than those grazed by sheep, irrespective of sward height treatment. This resulted in phase 2 in a higher proportion of white clover selected (P〈0.001), higher herbage intakes (P 〈 0.001) and higher liveweight gains (P 〈 0.001) by weaned lambs grazing swards previously grazed by goats compared with those previously grazed by sheep. There were higher proportions of clover present in the swards from treatment 4–8 at the beginning of phase 2 compared with the other sward height treatments and consequently weaned lambs had, on this treatment, a higher proportion of clover in their diet (P〈0.001), higher herbage intakes (P〈0001) and higher liveweight gains (P 〈0.001). It is concluded that goats can be integrated into sequential grazing systems with sheep on grass/clover swards and this can result in an increase in the proportion of clover in swards and increased sheep performance.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Grass and forage science 52 (1997), S. 0 
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: An experiment was conducted to examine how variation in the composition and structure of mixed grass/white clover swards affected diet selection by sheep and goats. Sward composition in a mixed perennial ryegrass/white clover sward was manipulated by continuous grazing from 28 May to 28 July (pre-experimental phase) with cattle, sheep or goats, and then from 29 July to 2 September (experimental phase) with sheep or goats in a factorial design replicated twice. Sward surface height was maintained at 6 cm by regular adjustment of stocking density. Grazing by different sequences of animal species resulted in significant differences in the proportions of white clover in the sward, and especially in the proportion of clover lamina and petiole. Grazing by goats in the pre-experimental phase led to greater proportions of clover lamina and petiole in the whole sward and the sward surface. The proportion of white clover in the diet selected by sheep in the experimental phase was consistently higher than that in the sward as a whole, but was closely related to that near to the sward surface (approximately the top 2 cm). For goats there was no significant relationship between the proportion of clover in the diet and in the whole sward, and they generally selected a diet with a lower proportion of white clover than was present in approximately the top 2 cm of the sward. It is concluded that on mixed grass/white clover swards goats do not graze as deeply into the sward as sheep and that this results in a lower proportion of white clover in their diet and therefore allows higher proportions of white clover to develop under grazing by goats than by sheep.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 33 (1995), S. 0 
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 34 (1996), S. 0 
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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