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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 19 (1972), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Multiple forms of calf brain N-acetyl-β-hexosaminidases (β-2-acetamido-2- deoxy-d-glucoside acetamidodeoxyglucohydrolase EC 3.2.1.30) were separated on starch gel electrophoresis at pH 5.8. The organ specific electrophoretic patterns did not depend on the cell fraction studied. Much of the activity is only separated with difficulty from particulate matter. Two major and one minor component were separated on DEAE-cellulose chromatography at pH 5.8. Each component had both N-acetyl-β-galactosaminidase and N-acetyl-β-glucosaminidase activity. The ratio of these two activities was unaffected by the presence of N-ethylmaleimide or dithiothreitol. The forms were also examined by isoelectric focusing when at least four components were recognized: isoelectric at 4.9, 6.0, 6.3 and 6.8. Interconversion of the 4.9 form to that isoelectric at pH 6.0 was noted during vacuum dialysis. Samples from normal human brain and from cases of Tay-Sachs disease were also examined and the results compared.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 45 (1990), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 31 (1996), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The distribution of basic fibroblast growth factor (bFGF) in periodontal ligament (PDL) tissue was investigated in samples which were obtained from freshly extracted human teeth. The PDL tissue was collected by scraping, and bFGF was identified and localized by immunohistochemistry. Fibroblasts. endothelial cells, some fibrocytes and extracellular matrix (ECM) stained positively for bFGF It was observed that cells from healthy PDL stained more intensely than those from PDL of teeth associated with chronic periodontitis; histological cell counts revealed that the numbers of fibroblasts was greater (p〈0.0005) in healthy PDL than in diseased PDL tissue. The results of this study show that bFGF is produced primarily by PDL fibroblasts and endothelial cells in the PDL and that bFGF levels may be decreased in tissue associated with chronic periodontal lesions.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 38 (1976), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The factors affecting the absorption and translocation of 14C-dalapon (2.2-dichloropropionic acid) in johnsongrass were studied. Johnsongrass [Sorghum halepense (L.) Pers.] was first pot-grown in a greenhouse and then treated and placed in controlled-environment chambers.Absorption of 14C-dalapon into johnsongrass leaves and subsequent translocation occurred continuously within the plant during a 48-h period after treatment. Gas chromatographic analysis of johnsongrass extracts showed that the dalapon molecule was translocated intact. Absorption and translocation of 14C-dalapon increased as the droplet volume of the diluent was increased from 0.2 to 5.0 μl per treated spot.At 21 and 32°C, translocation of 14C-dalapon from a 2-cm treated leaf section into the plant was greater at 100% than at 35% relative humidity. At 38°C, translocation was greater at 35% than at 100% relative humidity. The addition of 0.5% surfactant to the dalapon solution increased translocation under all environmental conditions studied. The addition of 0.1 M KH2PO4 to dalapon-surfactant solutions increased 4-dalapon translocation under high temperature (38°C), especially at 35% relative humidity.
    Type of Medium: Electronic Resource
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  • 5
    Publication Date: 2021-06-25
    Description: The assessment of earthquake forecast models for practical purposes requires more than simply checking model consistency in a statistical framework. One also needs to understand how to construct the best model for specific forecasting applications. We describe a Bayesian approach to evaluating earthquake forecasting models, and we consider related procedures for constructing ensemble forecasts. We show how evaluations based on Bayes factors, which measure the relative skill among forecasts, can be complementary to common goodness-of-fit tests used to measure the absolute consistency of forecasts with data. To construct ensemble forecasts, we consider averages across a forecast set, weighted by either posterior probabilities or inverse log- likelihoods derived during prospective earthquake forecasting experiments. We account for model correlations by conditioning weights using the Garthwaite–Mubwandarikwa capped eigenvalue scheme. We apply these methods to the Regional Earthquake Like- lihood Models (RELM) five-year earthquake forecast experiment in California, and we discuss how this approach can be generalized to other ensemble forecasting applications. Specific applications of seismological importance include experiments being conducted within the Collaboratory for the Study of Earthquake Predictability (CSEP) and ensemble methods for operational earthquake forecasting.
    Description: Published
    Description: 2574 – 2584
    Description: 4.2. TTC - Modelli per la stima della pericolosità sismica a scala nazionale
    Description: JCR Journal
    Description: restricted
    Keywords: earthquake forecasting ; ensemble model ; 04. Solid Earth::04.06. Seismology::04.06.02. Earthquake interactions and probability
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 6
    Publication Date: 2021-06-25
    Description: We cannot yet predict large earthquakes in the short term with much reliability and skill, but the strong clustering exhibited in seismic sequences tells us that earthquake probabilities are not constant in time; they generally rise and fall over periods of days to years in correlation with nearby seismic activity. Opera- tional earthquake forecasting (OEF) is the dissemination of authoritative information about these time-dependent proba- bilities to help communities prepare for potentially destructive earthquakes. The goal of OEF is to inform the decisions that people and organizations must continually make to mitigate seismic risk and prepare for potentially destructive earthquakes on time scales from days to decades. To fulfill this role, OEF must provide a complete description of the seismic hazard—ground-motion exceedance probabilities as well as short-term rupture probabilities—in concert with the long-term forecasts of probabilistic seismic-hazard analysis (PSHA).
    Description: Published
    Description: 955-959
    Description: 3T. Pericolosità sismica e contributo alla definizione del rischio
    Description: JCR Journal
    Description: reserved
    Keywords: Operational earthquake forecasting ; seismic preparedness ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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