Publication Date:
2014-02-05
Description:
Article The tumour suppressor PML is regulated by post-translational modification but the mechanism is unclear. Here, the authors show that PML is deubiquitinated and stabilized by USP11, which is in turn negatively regulated by the Notch signalling pathway. Nature Communications doi: 10.1038/ncomms4214 Authors: Hsin-Chieh Wu, Yu-Ching Lin, Cheng-Hsin Liu, Hsiang-Ching Chung, Ya-Ting Wang, Ya-Wen Lin, Hsin-I. Ma, Pang-Hsien Tu, Sean E. Lawler, Ruey-Hwa Chen
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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