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  • Nature Publishing Group (NPG)  (8)
  • BioMed Central  (4)
  • Hindawi  (2)
  • Cham :Springer International Publishing AG,  (1)
  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing AG,
    Keywords: Environmental management. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (182 pages)
    Edition: 1st ed.
    ISBN: 9783030762315
    DDC: 363.705
    Language: English
    Note: Intro -- Preface -- Contents -- Chapter 1: Introduction -- 1.1 Overview -- 1.2 Organization of This Book -- 1.2.1 Chapter 1: Introduction -- 1.2.2 Chapter 2: National and International Developments -- 1.2.3 Chapter 3: Climate Change and Built Environment -- 1.2.4 Chapter 4: Energy and Carbon Emission -- 1.2.5 Chapter 5: Materials and Water -- 1.2.6 Chapter 6: Sustainable Waste Management -- 1.2.7 Chapter 7: Sustainable Building Design -- 1.2.8 Chapter 8: Resilience and Adaptation in Buildings -- 1.3 Sustainability and Sustainable Development -- 1.3.1 Sustainability -- 1.3.2 Sustainable Development -- 1.3.3 Key Themes in Sustainable Development -- 1.3.4 Key Principles of Sustainable Development -- 1.3.5 Key Questions in Sustainable Development -- 1.4 Sustainable Construction -- 1.4.1 Overview -- 1.4.2 Life Cycle Approach in Sustainable Construction -- 1.4.3 Challenges of Sustainable Construction -- 1.5 Summary -- 1.6 Discussion Queries -- References -- Chapter 2: International and National Sustainable Developments -- 2.1 Introduction -- 2.2 International Developments -- 2.2.1 History of Sustainable Development -- 2.2.2 UN Policy on Sustainable Development -- 2.2.3 CIB Agenda 21 on Sustainable Construction -- 2.2.4 OECD Policies on Sustainable Development -- 2.2.5 ISO Policies on Sustainable Development -- 2.2.6 Melbourne Principles for Sustainable Cities -- 2.3 National Developments -- 2.3.1 Introduction -- 2.3.2 Australia's Commitment to International Sustainable Development -- 2.3.3 Council of Australian Government (COAG) Agreements -- 2.3.4 Federal Australian Government Actions -- 2.4 State and Territory Developments -- 2.5 Summary -- References -- Chapter 3: Climate Change and Built Environment -- 3.1 What Is Climate Change? -- 3.1.1 Climate System -- 3.1.2 Climate States -- 3.1.3 Greenhouse Effect -- 3.1.4 Sources of GHG -- 3.2 Climate Change. , 3.3 Global Warming -- 3.4 Carbon Cycle -- 3.5 Climate Projection -- 3.6 Global Climate Change-Observations -- 3.7 Climate Projection -- 3.8 Impact of Climate Change on Built Environment -- 3.9 Coping with Climate Change: Mitigation and Adaptation -- 3.9.1 Mitigation to Climate Change -- 3.9.2 Adaptation to Climate Change -- 3.10 Summary -- References -- Chapter 4: Energy and Carbon Emission -- 4.1 Introduction -- 4.2 Energy Sources, Production and Consumption -- 4.2.1 Primary and Secondary Energy Sources -- 4.2.2 The Energy Consumption -- 4.3 Energy per Capita and Human Development -- 4.4 Energy and CO2 Emission of Construction Sector -- 4.5 Embodied Energy -- 4.6 Operating Energy -- 4.6.1 Residential End Use -- 4.6.2 Commercial End Use -- 4.7 Energy Efficiency in Buildings -- 4.8 Carbon Accounting in Construction -- 4.8.1 Emissions from Fuel Combustion -- 4.8.2 Emissions from Electricity -- 4.9 Implications of Climate Change to Residential Building Energy -- 4.10 Summary -- References -- Chapter 5: Materials and Water -- 5.1 Introduction -- 5.2 Sustainable Resource Management -- 5.2.1 Global Material Consumption Trend -- 5.2.2 Sustainable Material Management -- 5.3 Sustainable Water Management -- 5.3.1 Overview -- 5.3.2 Water Efficiency and Recycling -- 5.3.3 Water Quality and Treatment -- 5.3.4 Rainwater Tanks -- 5.3.5 Desalination, Recycling and Energy -- 5.4 Summary -- References -- Chapter 6: Sustainable Waste Management -- 6.1 Introduction -- 6.2 Solid Waste Management: A Global and National View -- 6.2.1 Types of Solid Wastes -- 6.2.2 Impacts of Solid Waste -- 6.2.3 Construction and Demolition (C& -- D) Waste -- 6.3 Waste Treatments -- 6.4 Waste to Resource Management: A Circular Economy Approach -- 6.5 Challenges with Reuse and Recycling in the Construction Sector -- 6.6 Summary -- References -- Chapter 7: Sustainable Building Design. , 7.1 Introduction -- 7.2 Sustainable Building Design Opportunities -- 7.3 Green Building Design -- 7.4 Low-Energy Building Design -- 7.4.1 Building Orientation and Aspect Ratio -- 7.4.2 Building Envelope Design -- Building Envelope Design: Wall System -- Building Envelope Design: Windows -- Building Envelope Design: Roof -- 7.4.3 Daylighting Strategies -- 7.4.4 Ventilation Strategies -- 7.4.5 Thermal Mass and Insulation -- 7.4.6 Internal Load Reduction -- 7.5 Zero-Energy/Zero-Carbon Design -- 7.6 Summary -- References -- Chapter 8: Resilience and Adaptation in Buildings -- 8.1 Introduction -- 8.2 Sustainability -- 8.3 Built Environment -- 8.4 Climate Change Implications to Buildings -- 8.5 Resilience for Thermal Comfort -- 8.5.1 Thermal Comfort -- 8.5.2 Climate Change and Thermal Comfort -- 8.6 Resilience to Heat Waves -- 8.7 Resilience for Durability -- 8.7.1 Building Durability -- 8.7.2 Deterioration of Concrete Structures Under Changing Climate -- 8.7.3 Prevention of Concrete Deterioration -- 8.7.4 Durability of Timber -- 8.7.5 Deterioration of Timber Under Changing Climate -- 8.8 Summary -- References -- Chapter 9: Summary and Conclusions -- Index.
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  • 2
    Publication Date: 2015-02-28
    Description: Free nitrous acid (FNA), which is the protonated form of nitrite and inevitably produced during biological nitrogen removal, has been demonstrated to strongly inhibit the activity of polyphosphate accumulating organisms (PAOs). Herein we reported an efficient process for wastewater treatment, i.e., the oxic/anoxic/oxic/extended-idle process to mitigate the generation of FNA and its inhibition on PAOs. The results showed that this new process enriched more PAOs which thereby achieved higher phosphorus removal efficiency than the conventional four-step (i.e., anaerobic/oxic/anoxic/oxic) biological nutrient removal process (41 ± 7% versus 30 ± 5% in abundance of PAOs and 97 ± 0.73% versus 82 ± 1.2% in efficiency of phosphorus removal). It was found that this new process increased pH value but decreased nitrite accumulation, resulting in the decreased FNA generation. Further experiments showed that the new process could alleviate the inhibition of FNA on the metabolisms of PAOs even under the same FNA concentration. Scientific Reports 5 doi: 10.1038/srep08602
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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  • 3
    Publication Date: 2015-04-01
    Description: The effectiveness of grouting scheme has been simulated to prevent the coal spontaneous combustion at a goaf in Haizi Colliery, China. The colliery has been operated for long period over 27 years and has a complex ventilation network including airflow leakages which could possibly lead to the spontaneous combustion of coal at goafs. Firstly, the mine ventilation simulator MIVENA was used to analyze the mine ventilation network airflows to control airflows in and out of working faces and goafs. As the second approach, numerical simulations were carried by the simulator FLUENT in order to predict spontaneous combustion of residual coal with leakage flow in the #3205 goaf. It was cleared that the goaf can be divided into three zones based on oxygen concentration in the goaf area. Finally, the numerical simulation results show that the slurry grouting method is able to be an effective and economical method by reducing porosity in the goaf area to prevent spontaneous combustion of residual coal.
    Print ISSN: 1687-8833
    Electronic ISSN: 1687-8841
    Topics: Geosciences
    Published by Hindawi
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  • 4
    Publication Date: 2015-03-25
    Description: Background: Necrosis of alveolar macrophages following Mycobacterium tuberculosis infection has been demonstrated to play a vital role in the pathogenesis of tuberculosis. Our previous study demonstrated that Wnt/β-catenin signaling was able to promote mycobacteria-infected cell apoptosis by a caspase-dependent pathway. However, the functionality of this signaling in the necrosis of macrophage following mycobacterial infection remains largely unknown. Methods: Murine macrophage RAW264.7 cells were infected with Bacillus Calmette-Guerin (BCG) in the presence of Wnt/β-catenin signaling. The necrotic cell death was determined by cytometric assay and electronic microscopy; the productions of reactive oxygen species (ROS) and reduced glutathione (GSH) were measured by a cytometric analysis and an enzyme-linked immunosorbent assay, respectively; and the activity of poly (ADP-ribose) polymerase 1 (PARP-1)/apoptosis inhibition factor (AIF) signaling was examined by an immunoblotting assay. Results: The BCG can induce RAW264.7 macrophage cells necrosis in a dose- and time-dependent manner along with an accumulation of reactive oxygen species (ROS). Intriguingly, an enhancement of Wnt/β-catenin signaling shows an ability to reduce the mycobacteria-induced macrophage necrosis. Mechanistically, the activation of Wnt/β-catenin signaling is capable of inhibiting the necrotic cell death in BCG-infected RAW264.7 cells through a mechanism by which the Wnt signaling scavenges intracellular ROS accumulation and increases cellular GSH concentration. In addition, immunoblotting analysis further reveals that Wnt/β-catenin signaling is capable of inhibiting the ROS-mediated cell necrosis in part through a PARP-1/AIF- dependent pathway. Conclusions: An activation of Wnt/β-catenin signaling can inhibit BCG-induced macrophage necrosis by increasing the production of GSH and scavenging ROS in part through a mechanism of repression of PARP-1/AIF signaling pathway. This finding may thus provide an insight into the underlying mechanism of alveolar macrophage cell death in response to mycobacterial infection.
    Electronic ISSN: 1471-2172
    Topics: Medicine
    Published by BioMed Central
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  • 5
    Publication Date: 2015-04-11
    Description: Article Psoriasis is a chronic inflammatory disease affecting up to 3% of the population. Here, Zuo et al. perform exome array analysis, identify single-nucleotide polymorphisms at 15 new loci, implicating several biological pathways in psoriasis risk and disease heritability. Nature Communications doi: 10.1038/ncomms7793 Authors: Xianbo Zuo, Liangdan Sun, Xianyong Yin, Jinping Gao, Yujun Sheng, Jinhua Xu, Jianzhong Zhang, Chundi He, Ying Qiu, Guangdong Wen, Hongqing Tian, Xiaodong Zheng, Shengxiu Liu, Wenjun Wang, Weiran Li, Yuyan Cheng, Longdan Liu, Yan Chang, Zaixing Wang, Zenggang Li, Longnian Li, Jianping Wu, Ling Fang, Changbing Shen, Fusheng Zhou, Bo Liang, Gang Chen, Hui Li, Yong Cui, Aie Xu, Xueqin Yang, Fei Hao, Limin Xu, Xing Fan, Yuzhen Li, Rina Wu, Xiuli Wang, Xiaoming Liu, Min Zheng, Shunpeng Song, Bihua Ji, Hong Fang, Jianbin Yu, Yongxin Sun, Yan Hui, Furen Zhang, Rongya Yang, Sen Yang, Xuejun Zhang
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2016-06-09
    Description: The purpose of this study was to compare the efficacy and tolerability of the Ahmed glaucoma valve (AGV) implant and the Baerveldt implant for the treatment of refractory glaucoma.
    Electronic ISSN: 1471-2415
    Topics: Medicine
    Published by BioMed Central
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  • 7
    Publication Date: 2013-12-01
    Description: Article Whether microRNA processing mediated by Dicer is regulated in a cell-cycle-dependent manner is unknown. Here, Chen et al. show that Cyclin D1, which is important in the control of the cell cycle, regulates the expression of Dicer, and that Cyclin D1 and Dicer expression levels correlate in breast cancer. Nature Communications doi: 10.1038/ncomms3812 Authors: Zuoren Yu, Liping Wang, Chenguang Wang, Xiaoming Ju, Min Wang, Ke Chen, Emanuele Loro, Zhiping Li, Yuzhen Zhang, Kongming Wu, Mathew C. Casimiro, Michael Gormley, Adam Ertel, Paolo Fortina, Yihan Chen, Aydin Tozeren, Zhongmin Liu, Richard G. Pestell
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2018-10-23
    Description: Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II, Published online: 22 October 2018; doi:10.1038/s41467-018-06811-z Heterozygous loss of chromosome 17p is a common genomic event in castration-resistant prostate cancers (CRPC). Here, the authors use CRISPR-based screen to identify RBX1 as a target gene for CRPC with 17p loss and targeting RBX1 sensitizes CRPC to the treatment of α-amanitin antibody conjugates.
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2013-01-19
    Description: Nature Chemical Biology 9, 84 (2013). doi:10.1038/nchembio.1153 Authors: Gelin Wang, Xiaoming Wang, Hong Yu, Shuguang Wei, Noelle Williams, Daniel L Holmes, Randal Halfmann, Jacinth Naidoo, Lai Wang, Lin Li, She Chen, Patrick Harran, Xiaoguang Lei & Xiaodong Wang
    Print ISSN: 1552-4450
    Electronic ISSN: 1552-4469
    Topics: Biology , Chemistry and Pharmacology
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  • 10
    Publication Date: 2014-07-22
    Description: A large number of half-Heusler compounds have been recently proposed as three-dimensional (3D) topological insulators (TIs) with tunable physical properties. However, no transport measurements associated with the topological surface states have been observed in these half-Heusler candidates due to the dominating contribution from bulk electrical conductance. Here we show that, by reducing the mobility of bulk carriers, a two-dimensional (2D) weak antilocalization (WAL) effect, one of the hallmarks of topological surface states, was experimentally revealed from the tilted magnetic field dependence of magnetoconductance in a topologically nontrivial semimetal LuPdBi. Besides the observation of a 2D WAL effect, a superconducting transition was revealed at Tc ~ 1.7 K in the same bulk LuPdBi. Quantitative analysis within the framework of a generalized BCS theory leads to the conclusion that the noncentrosymmetric superconductivity of LuPdBi is fully gapped with a possibly unconventional pairing character. The co-existence of superconductivity and the transport signature of topological surface states in the same bulk alloy suggests that LuPdBi represents a very promising candidate as a topological superconductor. Scientific Reports 4 doi: 10.1038/srep05709
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
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