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  • Bentham Science Publishers Ltd.  (4)
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  • Bentham Science Publishers Ltd.  (4)
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  • 1
    Online Resource
    Online Resource
    The Potential Migrated Mechanism of Water-Soluble Components in Pellets Prepared by Wet Extrusion/Spheronization: Effect of Drying Rate
    Bentham Science Publishers Ltd. ; 2021
    In:  Current Drug Delivery Vol. 18, No. 6 ( 2021-09-20), p. 712-720
    Details
    In: Current Drug Delivery, Bentham Science Publishers Ltd., Vol. 18, No. 6 ( 2021-09-20), p. 712-720
    Abstract: At present, there are numerous researches on the migration of components in tablets and granules, however, the investigation in the pharmaceutical literatures concerning the effect of drying rate on the migration of water-soluble components of pellets is limited. Temperature and Relative Humidity (RH) are crucial parameters during the drying process, which is an essential step in the preparation of pellets via wet extrusion/spheronization. To quantify these variables, the water loss percentage of pellets per minute is defined as the drying rate. Aim: The study aimed to investigate the influence of drying rate on the migration of water-soluble components in wet pellets and the potential migrated mechanism. Methods: The pellets containing tartrazine as a water-soluble model drug and microcrystalline cellulose as a matrix former were prepared by extrusion/spheronization and dried at four different drying temperatures and relative humidity. Afterwards, the extent of migrated tartrazine was assessed regarding appearance, in-vitro dissolution test, Differential Scanning Calorimetry, X-Ray Powder Diffraction, Attenuated total reflectance Fourier transform infrared spectroscopy and Confocal Raman Mapping. Results: Results demonstrated that red spots of tartrazine appeared on the surface of pellets and more than 40% tartrazine were burst released within 5 minutes when pellets were dried at 60°C/RH 10%. When pellets were dried at 40°C/RH 80%, none of these aforementioned phenomena were observed. Conclusion: In conclusion, the faster the drying rate was, the more tartrazine migrated to the exterior of pellets. Adjusting drying temperature and relative humidity appropriately could inhibit the migration of water-soluble components within wet extrusion/spheronization pellets.
    Type of Medium: Online Resource
    ISSN: 1567-2018
    URL: Article
    DOI: 10.2174/1567201817666201124113741
    Language: English
    Publisher: Bentham Science Publishers Ltd.
    Publication Date: 2021
    SSG: 15,3
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Research Progress on Gear Transmission System Dynamics
    Bentham Science Publishers Ltd. ; 2023
    In:  Recent Advances in Electrical & Electronic Engineering (Formerly Recent Patents on Electrical & Electronic Engineering) Vol. 16 ( 2023-07-14)
    Details
    In: Recent Advances in Electrical & Electronic Engineering (Formerly Recent Patents on Electrical & Electronic Engineering), Bentham Science Publishers Ltd., Vol. 16 ( 2023-07-14)
    Abstract: The dynamics research of gear transmission systems mainly revolves around "excitation-model-response". The increasing number of dynamic incentive factors considered in the study has brought new problems to selecting modeling and solution methods and analyzing dynamic characteristics. Objective: This study aims to sort out the main research content of gear transmission system dynamics. Moepver, the commonly used analysis models, modeling, and solution methods are compared, and references for method selection and in-depth research are provided. Methods: This paper reviews the representative papers and patents related to the dynamic analysis of the gear system. The main contents of the dynamic excitation, dynamic model and dynamic characteristic analysis of the gear system are discussed, and suggestions for future development directions are given. Results: The dynamic excitations mainly considered in the current research are internal excitations and external excitations; random excitations are rarely considered. This paper analyzes and summarizes the commonly used modeling methods, model classification, solution methods, and dynamic characteristics research content. The advantages and disadvantages of several commonly used analysis models, modeling, and solution methods and their applicable occasions are summarized for the reference of researchers. Conclusion: The dynamics study of the gear system is a systematic work. It requires comprehensively considering the influence of dynamic excitations and selecting appropriate methods to establish and solve the model to obtain the dynamic characteristics that can better reflect the actual working conditions of the gear system. It is of great significance to improve the performance of the gear system.
    Type of Medium: Online Resource
    ISSN: 2352-0965
    URL: Article
    DOI: 10.2174/2352096516666230714141145
    Language: English
    Publisher: Bentham Science Publishers Ltd.
    Publication Date: 2023
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    Online Resource
  • 3
    Online Resource
    Online Resource
    A Kind of Electro-hydraulic Servo System Cooperative Control Simulation: An Experimental Research
    Bentham Science Publishers Ltd. ; 2022
    In:  Recent Advances in Electrical & Electronic Engineering (Formerly Recent Patents on Electrical & Electronic Engineering) Vol. 15, No. 4 ( 2022-06), p. 309-322
    Details
    In: Recent Advances in Electrical & Electronic Engineering (Formerly Recent Patents on Electrical & Electronic Engineering), Bentham Science Publishers Ltd., Vol. 15, No. 4 ( 2022-06), p. 309-322
    Abstract: The single position control or force control of the electro-hydraulic servo system has long been unable to meet the actual needs of production and life. To achieve a good control effect and solve various problems in real life, people no longer only consider a single position control or force control. Objective: The proposed method provides technical support for multi-objective collaborative control of the electro-hydraulic servo system, completes the requirements of multitasking operation, improves the positioning accuracy and response velocity of the electro-hydraulic servo system, and realizes the synergy between the position and force. Methods: A control method of the outer loop control of force as feedforward compensation is adopted to realize the coordinated control of force and position based on position control. The position control part adopts the PID control algorithm to ensure real-time response accuracy and positioning accuracy. The outer force loop uses an adaptive fuzzy neural network control algorithm to reduce vibration and shock caused by system instability and nonlinear factors during the force control process. Results: The control effect of the designed position/force collaborative controller is verified by simulation and experiment. It can effectively reduce the vibration and impact caused by the contact force during the working process of the system, at the same time greatly improving the accuracy of position control and improving the stability of the system. Conclusion:: The designed force/position collaborative control system has a good overall control effect.
    Type of Medium: Online Resource
    ISSN: 2352-0965
    URL: Article
    DOI: 10.2174/2352096515666220331143634
    Language: English
    Publisher: Bentham Science Publishers Ltd.
    Publication Date: 2022
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    Online Resource
  • 4
    Online Resource
    Online Resource
    Application of 3D Printing Technology in the Medical Field
    Bentham Science Publishers Ltd. ; 2022
    In:  Recent Advances in Electrical & Electronic Engineering (Formerly Recent Patents on Electrical & Electronic Engineering) Vol. 15, No. 8 ( 2022-12), p. 621-633
    Details
    In: Recent Advances in Electrical & Electronic Engineering (Formerly Recent Patents on Electrical & Electronic Engineering), Bentham Science Publishers Ltd., Vol. 15, No. 8 ( 2022-12), p. 621-633
    Abstract: 3D printing technology is widely used, with its application majorly prevailing in the medical field. Objective: In this paper, the applications of 3D printing technology in the medical field are classified and summarized, and their characteristics are introduced. Methods: This paper mainly summarizes the contribution of 3D printing technology to the field of medicine, as well as four applications of 3D printing technology in medicine, and also introduces some examples of clinical application of 3D printing. Results: 3D printing has proved to be an emerging art and a new innovation. It has a variety of different medical applications. Because of its limitations, it is not routinely used in clinical practice. However, it will be open to the public in the near future due to technological advances. It will provide new opportunities for every healthcare provider and seeker, and it will become a modern technology for innovative medical practices. Conclusion: 3D printing technology has been significantly developed and applied to oral cavity, implants and even human organs in the medical field，and shows a vigorous development trend. It is believed that this technology will significantly benefit mankind in the future.
    Type of Medium: Online Resource
    ISSN: 2352-0965
    URL: Article
    DOI: 10.2174/2352096515666221006142356
    Language: English
    Publisher: Bentham Science Publishers Ltd.
    Publication Date: 2022
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    Online Resource
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