In:
Current Respiratory Medicine Reviews, Bentham Science Publishers Ltd., Vol. 17, No. 4 ( 2021-11), p. 209-225
Abstract:
Conventional spirometry has long been considered the primary test for assessing respiratory
function deficits in children and adults. However, the need to perform forced breathing maneuvers can make it challenging to perform these examinations in an uncooperative child. For these
reasons, techniques such as gas dilutions and the multiple-breath-washout (MBW) method have been implemented because they allow for early assessment of damage to the small airways. These
methods permit the determination of the possible presence of ventilatory inhomogeneity in the lungs by analyzing the clearance of an inert gas used as a tracer. The equipment consists of a mass
spectrometer combined with a flow meter. The Lung Clearance Index (LCI) is most often used to evaluate ventilatory inhomogeneity. This narrative review aimed to review the literature on technical
and practical aspects of the MBW test and evaluate the clinical implications of the LCI in pediatric respiratory disease.
Type of Medium:
Online Resource
ISSN:
1573-398X
DOI:
10.2174/1573398X17666211201092525
Language:
English
Publisher:
Bentham Science Publishers Ltd.
Publication Date:
2021
Permalink
