In:
Beilstein Journal of Organic Chemistry, Beilstein Institut, Vol. 10 ( 2014-01-28), p. 282-286
Abstract:
Substituted 3,4-dihydro-1,8-naphthyridin-2(1 H )-ones have been synthesized with the inverse electron-demand Diels–Alder reaction from 1,2,4-triazines bearing an acylamino group with a terminal alkyne side chain. Alkynes were first subjected to the Sonogashira cross-coupling reaction with aryl halides, the product of which then underwent an intramolecular inverse electron-demand Diels–Alder reaction to yield 5-aryl-3,4-dihydro-1,8-naphthyridin-2(1 H )-ones by an efficient synthetic route.
Type of Medium:
Online Resource
ISSN:
1860-5397
Language:
English
Publisher:
Beilstein Institut
Publication Date:
2014
detail.hit.zdb_id:
2192461-2
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