In:
Bangladesh Journal of Pharmacology, Bangladesh Academy of Sciences, Vol. 11, No. 3 ( 2016-06-02), p. 577-
Abstract:
〈 p class="Abstract" 〉 〈 em 〉 Alchemilla mollis 〈 /em 〉 , is used in traditional medicine for the treatment of wounds and excessive menstruation. Aqueous methanol extracts of 〈 em 〉 A. mollis 〈 /em 〉 and 〈 em 〉 A. persica 〈 /em 〉 were evaluated for wound healing acivity by using linear incision and circular excision wound models along with hydroxyproline estimation and histopathological analysis. Anti-inflammatory effect was determined according to Whittle method. The extracts prepared from the aerial parts of 〈 em 〉 A. mollis 〈 /em 〉 and 〈 em 〉 A. persica 〈 /em 〉 exerted significant wound healing activity with the tensile strength values of 39.3% and 33.3%, respectively, and with the contraction values of 51.4% and 43.5%, respectively. Hydroxyproline estimation and histopathological analysis also confirmed the results. The extracts of 〈 em 〉 A. mollis 〈 /em 〉 and 〈 em 〉 A. persica 〈 /em 〉 showed significant anti-inflammatory activity with the values of 30.6% and 26.6% respectively. These results showed that 〈 em 〉 A. mollis 〈 /em 〉 and 〈 em 〉 A. persica 〈 /em 〉 possess significant wound healing and anti-inflammatory activities. 〈 /p 〉 〈 p class="Abstract" 〉 〈 strong 〉 Video Clip 〈 /strong 〉 〈 /p 〉 〈 p class="Subheading" 〉 〈 a href="https://youtube.com/v/k2Hz7f1e4SI" 〉 Circular excision wound model 〈 /a 〉 : 2 min 〈 /p 〉 〈 p 〉 〈 /p 〉
Type of Medium:
Online Resource
ISSN:
1991-0088
DOI:
10.3329/bjp.v11i3.26024
Language:
Unknown
Publisher:
Bangladesh Academy of Sciences
Publication Date:
2016
detail.hit.zdb_id:
2410466-8
SSG:
15,3
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