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  • 1
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    Clinical Outcome of Surgical Diathermy in Elective Surgery-Prospective Randomized Controlled Tria
    Bangladesh Academy of Sciences ; 2019
    In:  KYAMC Journal Vol. 10, No. 3 ( 2019-12-23), p. 143-146
    Details
    In: KYAMC Journal, Bangladesh Academy of Sciences, Vol. 10, No. 3 ( 2019-12-23), p. 143-146
    Abstract: Background: Recent studies suggest that surgical diathermy shows better clinical outcome in the context of incision time, wound related postoperative pain, postoperative wound infections, and length of postoperative hospital stay and cosmetic outcome of scar in cases of elective surgical patients. Objectives: Compare the efficacy and safety of surgical diathermy versus conventional surgical blade for making skin incisions in elective mid-line laparotomy and to evaluate weather cutting diathermy is an effective and better alternative to surgical blade incision. Materials and Methods: This prospective study was carried out in the department of surgery at BSMMU, Dhaka over a period of one year. Sample size was 64 with a follow up duration for 6 month. In Group I (D), skin incision was taken with diathermy, and in Group II (S), incision was taken with surgical blade. Results: Compared with a scalpel incision, cutting diathermy resulted in significantly shorter incision times and reduced post-operative wound related pain (P = 〈 0·001), shorter duration of postoperative hospital stay (P = 0.003) with no differences in the wound complication rate and cosmetic outcome of scar. Conclusions: The study has demonstrated that surgical cutting diathermy is a safe and effective method to make skin incisions in elective surgery KYAMC Journal Vol. 10, No.-3, October 2019, Page 143-146
    Type of Medium: Online Resource
    ISSN: 2308-2860 , 2308-2720
    URL: Article
    DOI: 10.3329/kyamcj.v10i3.44417
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2019
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  • 2
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    Incidence and Clinical Significance of Cardiac Murmur in Neonates in a Tertiary Hospital
    Bangladesh Academy of Sciences ; 2018
    In:  TAJ: Journal of Teachers Association Vol. 30, No. 2 ( 2018-12-03), p. 54-59
    Details
    In: TAJ: Journal of Teachers Association, Bangladesh Academy of Sciences, Vol. 30, No. 2 ( 2018-12-03), p. 54-59
    Abstract: Background: Congenital cardiac defect is the major cause of mortality and morbidity in our country but maximum cases are undetected due to lack of skill, shortage of man power, modern equipment in peripheral hospitals. But simply observing murmur can give us the clue for underlying congenital heart diseases.Objectives: The purpose of this study is to determine the incidence and clinical significance of cardiac murmur in neonates in a tertiary level hospital in Rajshahi.Methods: This cross-sectional descriptive study was done in neonates (age ≤ 28 days) in Rajshahi Medical College Hospital from January 2014 to December 2015.Results: during this study period total 4120 neonates were admitted in neonatal ward and only 52 cases were presented with cardiac murmur clinically. Incidence rate of murmur was 1.26%. Among 52 cases 40 cases were having pathological murmur and 12 cases were having innocent murmur. After doing echocardiogram 34 cases were showing structural cardiac defect out of 40 pathological murmur and 4 cases were showing structural cardiac defect out of 12 innocent murmur. Total cases of structural cardiac defect (congenital heart disease) were 38(34+4). So, incidence of congenital heart disease was 9.22/ 1000 live births.Conclusion: Congenital cardiac defect is the major cause of mortality and morbidity in our country but maximum cases are undetected during neonatal period but simply observing murmur can give us the clue for underlying congenital heart diseases in 73.08% cases (38 were congenital heart disease out of 52 cases). If congenital heart disease is early detected and properly managed many valuable lives of neonates can be saved and their growth and development will be smooth.TAJ 2017; 30(2): 54-59
    Type of Medium: Online Resource
    ISSN: 2408-8854 , 1019-8555
    URL: Article
    DOI: 10.3329/taj.v30i2.39138
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
    detail.hit.zdb_id: 2754944-6
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  • 3
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    Effect of Preoperative Internal Biliary Drainage on Postoperative Outcome Following Pancreaticoduodenectomy for Periampullary Carcinoma
    Bangladesh Academy of Sciences ; 2020
    In:  KYAMC Journal Vol. 10, No. 4 ( 2020-03-01), p. 196-201
    Details
    In: KYAMC Journal, Bangladesh Academy of Sciences, Vol. 10, No. 4 ( 2020-03-01), p. 196-201
    Abstract: Background: Preoperative biliary drainage before pancreaticoduodenectomy is a controversial issue. Proponents are in favor of preoperative biliary drainage by ERCP with stent to reduce surgical jaundice with an anticipation of better surgical outcome. Objective: Compare the outcome with or without pre-operative biliary drainage before pancreaticoduodenectomy. Materials and Methods: This observational comparative study was conducted in department of Surgery and Hepatobiliary and pancreatic surgery of BSMMU. Twenty three patients presented with obstructive jaundice due to periampulary carcinoma who subsequently underwent pancreaticoduodenectomy were selected by purposive sampling and finalized by eligibility criteria. Results: Patients with preoperative biliary drainage (PBD) group required a longer operative time (mean 4.12 hours versus 3.83 hours) and had more intra-operative blood loss (mean 662 mL versus 495 mL) compared with non PBD group (P=0.009 and 0.010). No differences were found with respect to operative mortality (4.3%) and incidence of pancreatic leakage (P=0.281). PBD was significantly associated with positive bile culture (P=0.019) and high incidence of wound infection (p=0.029). Conclusion: Preoperative biliary drainage did not increase major postoperative morbidity and mortality but associated with increased operative time, intraoperative blood loss, and incidence of wound infection. Preoperative biliary drainage should be used selectively in patients undergoing pancreaticoduodenectomy. KYAMC Journal Vol. 10, No.-4, January 2020, Page 196-201
    Type of Medium: Online Resource
    ISSN: 2308-2860 , 2308-2720
    URL: Article
    DOI: 10.3329/kyamcj.v10i4.45719
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2020
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  • 4
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    Association of Ankle Brachial Pressure Index (ABPI) in Patients with Ischemic Stroke : A Case Control Study
    Bangladesh Academy of Sciences ; 2013
    In:  Chattagram Maa-O-Shishu Hospital Medical College Journal Vol. 12, No. 3 ( 2013-10-28), p. 27-33
    Details
    In: Chattagram Maa-O-Shishu Hospital Medical College Journal, Bangladesh Academy of Sciences, Vol. 12, No. 3 ( 2013-10-28), p. 27-33
    Abstract: Background: Several epidemiological studies have identified the association of abnormal ABPI with ischemic stroke. So the goal of this study was to determine the actual relationship of ABPI with ischemic stroke in the context of our country. Methods: This case control study was carried out in the Department of Neurology, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh. ABPI was measured by Doppler ultrasound machine of 100 patients who were admitted to the Mitford Hospital during the study period. Among them 50 patients with Ischemic stroke, confirmed by CT/MRI scan of brain were considered as case and 50 age-sex matched individuals with one or more vascular risk factors (VRF) but without stroke were considered as control. Then the results of ABPI were compared between the two groups. Results: Among the 50 patients with ischemic stroke (case group), 74% had normal ABPI and 26% had ABPI 〈 0.9; on the other hand among 50 age and sex matched individuals (control group) 90% had normal ABPI and 10% had ABPI 〈 0.9. The difference was statistically significant between two groups. (p= 〈 0.05).This association remained significant even after adjustment for potential confounders (age, gender, high BMI, hypertension, diabetes mellitus, hyperlipidemia, smoking, ischemic heart disease and family history) in a multiple logistic regression model. Conclusion: The incidence of low ABPI is significantly higher in ischemic stroke patients than the age- sex matched control. Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 27-33
    Type of Medium: Online Resource
    ISSN: 2306-4919 , 2305-7890
    URL: Article
    DOI: 10.3329/cmoshmcj.v12i3.16710
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
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  • 5
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    Routine Histopathological Examination After Cholecystectomy
    Bangladesh Academy of Sciences ; 2020
    In:  KYAMC Journal Vol. 10, No. 4 ( 2020-03-01), p. 184-187
    Details
    In: KYAMC Journal, Bangladesh Academy of Sciences, Vol. 10, No. 4 ( 2020-03-01), p. 184-187
    Abstract: Background: Cholecystectomy is one of the commonest surgeries in medical practice. Sometimes malignant condition cannot be assessed pre-operatively. Histopathology require for tissue diagnosis. Objective: To assess whether the histopathogical examination is really needed for all bladder specimens resected for cholelithiasis and cholecystitis. Materials and Methods: This observational study was carried out in the General Surgery Unit, Department of Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka from May, 2016 to April, 2017. A total number of 95 patients were included in this study. Results: Total of 95 gallbladder specimens were submitted for histopathological examination where 33.7% were males and 66.3 % were females with mean age of 46+12.86 years. Chronic cholecystitis was the most common finding in 91.6% of cases whereas Xanthogranulomatous 2.1%. Six of the gall bladders showed adenocarcinoma (6.3%), of which four had changes on ultrasound and macroscopic gall bladder analysis (MGAS) disturbances were found in 5 cases and 1 case was found incidentally on histopathological examination. On ultrasound, only four (66.66%) and peroperative macroscopic examination by surgeon only 5(83.3%) had a clue of carcinoma. Conclusion: It could be concluded that , routine histopathological examination of gallbladder after cholecystectomy is necessary as USG sometimes can not differentiate neoplastic lesion from inflammatory one. KYAMC Journal Vol. 10, No.-4, January 2020, Page 184-187
    Type of Medium: Online Resource
    ISSN: 2308-2860 , 2308-2720
    URL: Article
    DOI: 10.3329/kyamcj.v10i4.45716
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2020
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  • 6
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    Magnetic Resonance Imaging-Based Evaluation of the Etiology of Non-Traumatic Myelopathies in Bangladesh: A Hospital-based Observational Cross-sectional Study from Two Tertiary Care Centers of Dhaka
    Bangladesh Academy of Sciences ; 2018
    In:  Journal of National Institute of Neurosciences Bangladesh Vol. 4, No. 2 ( 2018-12-10), p. 87-91
    Details
    In: Journal of National Institute of Neurosciences Bangladesh, Bangladesh Academy of Sciences, Vol. 4, No. 2 ( 2018-12-10), p. 87-91
    Abstract: Background: Non-traumatic myelopathies has several etiologies.Objectives: The aim of the study was to see the etiology of non-traumatic myelopathy based on magnetic resonance imaging (MRI) changes in the context of Bangladesh.Methodology: Patients clinically diagnosed as non-traumatic myelopathy in the department of neurology of Sir Salimullah Medical College and Hospital (SSMCH), and in the inpatient wards of the National Institute of Neurosciences (NINS), considering the inclusion and exclusion criteria were enrolled as the study population from May 2014 to December 2015. Age, gender, clinical presentations and type of lesion based on MRI changes were collected. All the data were analyzed statistically.Results: Total 100 cases satisfied the inclusion and exclusion criteria in this study. Among them, there were 62 males and 38 females with a male to female ratio of 1.63:1. The mean age was found to be (mean ± SD) 45.80 ±15.28 with age ranges from 15 to 74 years. The highest number of patients (26.0%) was in the age group 51-60 years, followed by 24% patients in the age group 31-40 years. Based on MRI scan, most common etiologies that commonly diagnosed are cervical spondylotic myelopathy (31%), transverse myelitis (26%), primary spinal tumour (13%), spinal tuberculosis(12%), spinal metastatic disease (12%), and unclassified (6%). MRI scan also detect the common sites of involvements of these causes.Conclusion: In this study cervical spondylotic myelopathy, transverse myelitis, and spinal tuberculosis are the most common cause of non-traumatic myelopathy in the context of Bangladesh.Journal of National Institute of Neurosciences Bangladesh, 2018;4(2): 87-91
    Type of Medium: Online Resource
    ISSN: 2410-8030
    URL: Article
    DOI: 10.3329/jninb.v4i2.38920
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
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  • 7
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    Diagnostic Role of Adenosine Deaminase (ADA) among Tuberculous Meningitis Patients
    Bangladesh Academy of Sciences ; 2013
    In:  Bangladesh Journal of Neuroscience Vol. 29, No. 2 ( 2013-07-31), p. 79-87
    Details
    In: Bangladesh Journal of Neuroscience, Bangladesh Academy of Sciences, Vol. 29, No. 2 ( 2013-07-31), p. 79-87
    Abstract: Background: In the developing countries where TB is endemic; an ideal test for tuberculous meningitis should be economic, minimally invasive, of high accuracy and quick to perform.In many countries, also in India, several studies were conducted to establish the ADA activity as a sensitive and specific test of tuberculous meningitis.So it is very much needed to evaluate the diagnostic role of CSF ADA in tuberculous meningitis in Bangladesh. Aim: This study aimed to find out CSF ADA as a sensitive and specific test for early diagnosis of tuberculous meningitis. Methods: This case control study was carried out in the Department of Neurology, SSMC and Mitford Hospital, Dhaka from June 2011 to July 2012, to evaluate ADA activity in CSF for diagnosis of tuberculous meninigitis. Results: In the present study, sixty meningitis patients were enrolled. Of which, 30(50%) were tuberculous meningitis (TBM) taken as cases and rest 30(50%) were non-tuberculous meningitis (NTBM) taken as control.The CSF ADA activity from TBM patients was compared with CSF ADA from non-TBM infectious meningitis patients. The mean CSF ADA activity was found to be significantly higher in CSF of TBM patients, 14.01 ± 12.4 (1.0–65.2), mean ± SD with range, than in the CSF from non-TBM infectious meningitis, 7.2 ± 8.2 (1.8–49.1) P = 0.01.A cut-off value of 〉 7.6 U/L for the TBM patients was calculated from the mean ±SD of the non-TBM patients.The ADA sensitivity is 81.82%,specificity 65.31%,accuracy 68.33%, PPV 34.62%,NPV 94.12%, positive likelyhood ratio 2.3 and lastly negative likelyhood ratio 0.2 for infectious TBM when this cut-off value was used.ROC curve shows area under curve of .736 suggests a moderate accuracy of the test in detection of tuberculous meningitis. Conclusion: This study demonstrated that ADA activity in the CSF of TBM patients, using a cut off value 7.6 U/L, can be useful for the early differential diagnosis of TBM. This test can be performed in any pathology laboratory where more sophisticated methods are not available. Bangladesh Journal of Neuroscience 2013; Vol. 29 (2) : 79-87
    Type of Medium: Online Resource
    ISSN: 2408-8382 , 1023-4853
    URL: Article
    DOI: 10.3329/bjn.v29i2.56176
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
    detail.hit.zdb_id: 2573887-2
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  • 8
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    Computational Study of Solvation Free Energy, Dipole Moment, Polarizability, Hyperpolarizability and Molecular Properties of Betulin, a Constituent of Corypha taliera (Roxb.)
    Bangladesh Academy of Sciences ; 2017
    In:  Dhaka University Journal of Pharmaceutical Sciences Vol. 16, No. 1 ( 2017-07-30), p. 1-9
    Details
    In: Dhaka University Journal of Pharmaceutical Sciences, Bangladesh Academy of Sciences, Vol. 16, No. 1 ( 2017-07-30), p. 1-9
    Abstract: Ab initio calculations were carried out to studysolvation free energy, dipole moment, molecular electrostatic potential (MESP), Mulliken charge distribution, polarizability, hyperpolarizability and different molecular properties like global reactivity descriptors (chemical hardness, softness, chemical potential, electronegativity, electrophilicity index) of betulin. B3LYP/6-31G(d,p) level of theory was used to optimize the structure both in gas phase and in solution. The solvation free energy, dipole moment and molecular properties were calculated by applying the Solvation Model on Density (SMD) in six solvent systems namely water, dimethyl sulfoxide (DMSO), acetonitrile, n-octanol, chloroform and carbontetrachloride. The solvation free energy of betulin increases with decreasing polarity of the solvent. No systematic trend of hyperpolarizability with solvent polarity is found. Molecular electrostatic potential (MESP) and Mulliken population analysis (MPA) reveal that the most possible sites for nucleophilic attack are C30, H76 and H77 and electrophilic attack are O1 and O2 among the atoms in betulin. However, the dipole moment, polarizability, chemical potential, electronegativity and electrophilicity index of betulin increase on going from non-polar to polar solvents. Chemical hardness was also increased with decreasing polarity of the solvent and opposite relation was found in the case of softness. These results provide better understanding of the stability and reactivity of betulin in different solvent systems.Dhaka Univ. J. Pharm. Sci. 16(1): 1-9, 2017 (June)
    Type of Medium: Online Resource
    ISSN: 1816-1839 , 1816-1820
    URL: Article
    DOI: 10.3329/dujps.v16i1.33376
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2017
    detail.hit.zdb_id: 2409209-5
    SSG: 15,3
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  • 9
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    The Relationship between Risk Factors and Microalbumiuria for Ischemic Stroke- A Case Control Study
    Bangladesh Academy of Sciences ; 2013
    In:  Bangladesh Journal of Neuroscience Vol. 29, No. 1 ( 2013-01-31), p. 43-53
    Details
    In: Bangladesh Journal of Neuroscience, Bangladesh Academy of Sciences, Vol. 29, No. 1 ( 2013-01-31), p. 43-53
    Abstract: Background: Epidemiologic studies have reported that microalbuminuria is a risk factor for stroke in men and a limited case control study found that the highest quintile of microalbuminuria values was associated with 13 fold increased risk for stroke. The goal of this study was designed to determine its relationship to risk factors for ischemic stroke. Materials and Methods: It was a prospective observational study conducted in the Department of Neurology, Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh. Fifty consecutive patients with ischemic stroke were enrolled in this study, with at least two risk factors that fulfilled the inclusion criteria and were confirmed by CT or MRI of brain. Equal number of controls of same age group without stroke who had at least two risk factors was compared with the case group. The patients were assessed clinically with structured questionnaire including blood pressure, height and weight, and monitoring blood glucose and microalbuminuria. Results: Microalbuminuria was found 58.0% in patients with ischemic stroke. Patients who had diabetes mellitus will have 13.86 times the risk for developing of microalbuminuria (p 〈 0.05). Patients who had hypertension will have 4.19 times the risk of developing microalbuminuria (p 〈 0.05) and BMI (e”23 kg/m2) will have 4.24 times the risk of developing microalbuminuria (p 〈 0.05). Whereas TIA, IHD, dyslipidemia, smoking and positive family history were not significantly (P 〉 0.05) associated with microalbuminuria in patients with ischemic stroke. Conclusion: The findings of this study show that diabetes is the factor most closely associated with microalbuminuria followed by HTN and BMI 〉 23 kg/ m2 with statistically significance in patients with ischemic stroke. Bangladesh Journal of Neuroscience 2013; Vol. 29 (1) : 43-53
    Type of Medium: Online Resource
    ISSN: 2408-8382 , 1023-4853
    URL: Article
    DOI: 10.3329/bjn.v29i1.56170
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
    detail.hit.zdb_id: 2573887-2
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  • 10
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    Depression and Insomnia in Patients on Maintenance Hemodialysis
    Bangladesh Academy of Sciences ; 2016
    In:  Journal of Dhaka Medical College Vol. 24, No. 1 ( 2016-09-07), p. 3-11
    Details
    In: Journal of Dhaka Medical College, Bangladesh Academy of Sciences, Vol. 24, No. 1 ( 2016-09-07), p. 3-11
    Abstract: Depression and sleep disorders are more frequent in patients on maintenance hemodialysis (HD) than the general population, and are associated with reduced quality of life and increased mortality risk. The purpose of this study was to assess the prevalence of depression and insomnia in patients on HD and to correlate these with the demographic and biochemical profile. A cross sectional study was conducted among 316 patients on maintenance HD for more than 3 months. There was high prevalence of depression (92.7%) and insomnia (91.1%), Depression was significantly more in patients with urban population (P=0.007), unemployed patients (P=0.007), who had less income.(P=0.018) who got dialysis 〉 12 months (P=0.009) and who got dialysis 2 session per week (P value=0.014). Insomnia was found significantly more in female (P=0.018) and among thosepatients of less income group (P=0.008) and in patients who got at least two sessions of hemodialysis per week (P=0.011).Low serum hemoglobin isassociated with both depression and insomnia (P 〈 0.5), while low serum albumin concentration is found associated with depression (P 〈 0.5).J Dhaka Medical College, Vol. 24, No.1, April, 2015, Page 3-11
    Type of Medium: Online Resource
    ISSN: 2219-7494 , 1028-0928
    URL: Article
    DOI: 10.3329/jdmc.v24i1.29555
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2016
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