In:
World Journal of Gastroenterology, Baishideng Publishing Group Inc., Vol. 30, No. 7 ( 2024-2-21), p. 652-662
Abstract:
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 25% of the world's population and has become a leading cause of chronic liver disease. In recent years, an increasing amount of data suggests that MASLD is associated with aging. As the population ages, age-related MASLD will become a major global health problem. Targeting an aging will become a new approach to the treatment of MASLD. This paper reviews the current studies on the role of aging-related factors and therapeutic targets in MASLD, including: Oxidative stress, autophagy, mitochondrial homeostasis, bile acid metabolism homeostasis, and dysbiosis. The aim is to identify effective therapeutic targets for age-related MASLD and its progression.
Type of Medium:
Online Resource
ISSN:
1007-9327
DOI:
10.3748/wjg.v30.i7.652
Language:
Unknown
Publisher:
Baishideng Publishing Group Inc.
Publication Date:
2024
detail.hit.zdb_id:
2084831-6
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