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  • 1
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Herbage characteristics were studied over years 4–6 (1988–90) in three perennial ryegrass (Lolium perenne L.) varieties as grass-only (200 kg N ha-1) and grass/clover (Trifolium repens L.) swards which received 75kg N ha-1 in 1988 and 0kg N ha-1 in 1989 and 1990 when continuously stocked with sheep. Mean total annual herbage production of Aurora, a very early flowering variety, was 11% more than that of late-flowering Aberystwyth S23 due to 21% higher growth as grass/clover pasture. The grass/clover sward of Meltra, a tetraploid late-flowering variety, out-yielded S23/clover by 17%. Herbage production of grass/clover was 86% of that of grass only in 1988 but only 54% of the grass-only swards averaged for 1989 and 1990. In vitro organic matter digestibility (OMD) of Meltra was 38g kg-1 OM and 27g kg-1 OM higher than that of S23 and Aurora respectively. OMD of grass/clover was 15g kg-1 OM higher than that of grass only during the post-weaning period. Herbage intake was positively correlated with OMD of herbage.The herbage attributes were related to lamb performance reported previously. Lamb output was positively correlated with intake of digestible organic matter.Differences between the three varieties in herbage characteristics were greater as grass/clover than as grass-only swards, reflecting their compatibility with white clover. In this respect Meltra was the best and S23 the poorest variety.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Relative sheep production from Aurora (very early flowering), Mellra (late-flowering tetraploid) and Aberystwyth S23 (late flowering) perennial ryegrass (Lolium perenne L.) varieties was compared during harvest years 4-6 (1988-90) as grass only (200 kg N ha−1) and grass/clover (75 kg N ha −1 in 1988, 0 kg N ha−1 in 1989 and 1990) at Bronydd Mawr Research Centre (310-363 m) in mid-Wales. The pastures were continuously stocked with Beulah Speckled Face ewes and their Suffolk cross lambs from spring to mid-July. From late July to early November only the weaned lambs grazed the swards.Mean (1988-90) total annual lamb production per hectare from Aurora and Meltra was 70% and 16% more than that from S23. However, the difference between both varieties and S23 was much greater as grass/clover (Aberystwyth S184 small-leaved type) than as grass-only swards. Differences between the grasses in individual lamb growth rates were most pronounced during the post-weaning period, when that on Meltra was 38% and 23% more than on Aurora and S23 respectively.Mean annual lamb output from grass/clover swards was only 70% of that from grass-only swards during the 2 years when the former swards received no fertilizer N. Averaged over the 3 years (1988-90) individual lamb liveweight gain post weaning was 38% higher on grass/clover than on grass-only swards.The results are discussed in relation to those for the first 3 harvest years (1985-87). It is concluded that, although Aurora was less persistent than both late-flowering varieties, its superiority in providing an average of 29% more lamb output than S23 during the critical spring period (up to early June) would be of considerable practical significance in upland sheep systems, as would be the overall superiority of the tetraploid Meltra over S23.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Plasma 17β-oestradiol, total unconjugated oestrogens and progesterone levels were measured in ten patients in the second trimester of pregnancy who were undergoing abortion by intra-amniotic injection of prostaglandin F2α (PGF2α). The correlation between total unconjugated plasma oestrogens and 17β-oestradiol was highly significant (r =+0.92; p〈0.001). A similar positive correlation between total unconjugated plasma oestrogen and progesterone was observed (r =+0.66; p〈0.001). The concentration of these steroids in samples, taken at intervals during normal pregnancy, showed considerable variation. Following administration of PGF2α no consistent change was seen in plasma steroid concentrations until after delivery of the fetus and placenta. PGF2α therefore appears to have no direct effect on oestrogen and progesterone biosynthesis and may act principally by direct stimulation of myometrial contractility.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 148 (1968), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 148 (1968), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 47 (1992), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The outcome of adult respiratory distress syndrome complicating cardiopulmonary bypass has changed little in recent years. A retrospective, case-controlled study was designed to assess the incidence of the adult respiratory distress syndrome in these circumstances and the extent to which it could be linked with pre and peri-operative predictive factors. Eleven patients who developed the syndrome out of 840 who underwent cardiopulmonary bypass over a 9 month period were compared with 53 controls matched for sex, operation and surgeon. The incidence of adult respiratory distress syndrome and its mortality were 1.3% and 53% respectively. Significant predictors were a high intra and postoperative intervention score, the total volume of blood pumped during bypass (〉300 l) and age (〉60 years). These risk factors should alert the clinician to the possibility of severe postoperative pulmonary complications.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Ground water 4 (1966), S. 0 
    ISSN: 1745-6584
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Geosciences
    Notes: The digital computer is used on a routine basis in the ground-water program in Kansas for tasks ranging from the listing of water-quality data in tabular and publishable form to statistically and graphically analyzing a mass of data.In the past year a number of computer programs in FORTRAN IV have been developed by Charles O. Morgan and Jesse M. McNellis using an IBM-7040 computer to store, retrieve, and manipulate water-quality data. These programs:(1) Tabulate data at the rate of 40 chemical analyses of water per minute in a format similar to that found in the Kansas ground-water publications.(2) Perform necessary calculations and print Stiff diagrams at the rate of 30 per minute.(3) Perform necessary calculations and print Piper diagrams, including a square modification of the normally diamond-shaped cation-anion diagram, and trilinear diagrams of the cations and anions. The symbol representing the analyses located on the diagrams can be designated by either an analysis number or a geologic unit number. A cation-anion diagram showing the average chemical composition of water for an aquifer can also be printed. These diagrams for 50 analyses can be produced in 1.5 minutes.(4) Plot maps of 42 individual, combined, or calculated parameters obtained from the data cards. These maps can be plotted to any specified scale and for as many as 10 designated geologic units. Computer time involved for one map with 50 plotted points is 15 seconds.It is estimated that the use of these programs will save several man-months during a ground-water study, and the error inherent in the manual manipulation of data is greatly reduced. The present cost for running 50 analyses through the four water-quality programs on the computer is approximately $20.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Grass and forage science 50 (1995), S. 0 
    ISSN: 1365-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Perennial ryegrass/white clover (Lolium perennel Trifolium repens) pastures of three white clover varieties were compared at UK lowland (Plas Gogerddan, PG) and upland (Bronydd Mawr, BM) sites over three harvest years (1989–91) under continuous variable stocking (ewes and lambs until weaning and lambs thereafter). Mean annual lamb output from small-leaved S 184 (1179 kg ha−1) was 29% greater than that from prostrate small-leaved AberEndura at PG with medium-leaved Huia also giving 19% more output than AberEndura. At BM, output from S 184 (863 kg ha−1) was 19 and 14% greater than that from AberEndura and Huia respectively. The differences in lamb output between the small-leaved varieties owed to a combined effect of higher individual lamb growth rates and greater stock-carrying capacity, both of which were more pronounced in the post-weaning period. The higher output from S 184 relative to Huia at BM was attributed to higher stocking rate, particularly after weaning. Clover productivity and persistence were also studied under three cutting-only managements at PG. Performance under a treatment cut at 2–3 cm every 10 d (T1), which is synonymous with assessment of persistence in UK National List testing, was poor with clover growing point number of only 498 m−2 compared with 4906 m−2 on the grazed sward in autumn 1991. Although productivity and clover content under T3 (cut at 3–4 cm every 42 d — similar to National List yield regime) gave the same varietal ranking as lamb production, there was an under-estimation of the small-leaved varieties, particularly AberEndura, relative to Huia. An intermediate treatment (T2), cut at 3–4 cm every 21 d, also over-estimated the performance of the medium-leaved variety. Herbage data from ground level sampling every 21 d using exclosure cages on the grazed swards were also poorly related to lamb performance. These results highlight the effect of clover variety on lamb production, which appeared to be independent of leaf size, and also confirm the existing problems associated with assessment of white clover varieties using a cutting regime.
    Type of Medium: Electronic Resource
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  • 9
    Publication Date: 2018-06-23
    Description: Introduction Cerebral palsy (CP) is the most common childhood physical disability, with 80% estimated to be in low-middle-income countries. This study aims to (1) determine the accuracy of General Movements (GMs)/Hammersmith Infant Neurological Examination (HINE) for detecting CP at 18 months corrected age (CA); (2) determine the effectiveness of a community-based parent-delivered early intervention for infants at high risk of CP in West Bengal, India (Learning through Everyday Activities with Parents for infants with CP; LEAP-CP). Methods This study comprises two substudies: (1) a study of the predictive validity of the GMs and HINE for detecting CP; (2) randomised, double-blinded controlled trial of a novel intervention delivered through peer trainers (Community Disability Workers, CDW) compared with health advice (15 fortnightly visits). 142 infants at high risk of CP (‘absent fidgety’ GMs; ‘high risk score’ on HINE) aged 12–40 weeks CA will be recruited to the intervention substudy, with infants randomised based on a computer-generated sequence. Researchers will be masked to group allocation, and caregivers and CDWs naïve to intervention status. Visits will include therapeutic modules (goal-directed active motor/cognitive strategies and LEAP-CP games) and parent education. Health advice is based on the Integrated Management of Childhood Illness, WHO. Infants will be evaluated at baseline, post intervention and 18 months CA. The primary hypothesis is that infants receiving LEAP-CP will have greater scaled scores on the Pediatric Evaluation of Disability Inventory—Computer Adaptive Test (mobility domain) at 18 months compared with health advice. Secondary outcomes include infant functional motor, cognitive, visual and communication development; infant growth; maternal mental health. Ethics and dissemination This study is approved through appropriate Australian and Indian ethics committees (see in text) with families providing written informed consent. Findings from this trial will be disseminated through peer-reviewed journal publications and conference presentations. Trial registration number 12616000653460p; Pre-results.
    Keywords: Public health, Open access, Global health
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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  • 10
    Publication Date: 2017-09-20
    Description: Objectives Congenital hemiplegia is the most common form of cerebral palsy (CP). Children with unilateral CP show signs of upper limb asymmetry by 8 months corrected age (ca) but are frequently not referred to therapy until after 12 months ca. This study compares the efficacy of infant-friendly modified constraint-induced movement therapy (Baby mCIMT) to infant friendly bimanual therapy (Baby BIM) on upper limb, cognitive and neuroplasticity outcomes in a multisite randomised comparison trial. Methods and analysis 150 infants (75 in each group), aged between 3 and 6 months ca, with asymmetric brain injury and clinical signs of upper extremity asymmetry will be recruited. Children will be randomised centrally to receive equal doses of either Baby mCIMT or Baby BIM. Baby mCIMT comprises restraint of the unimpaired hand using a simple restraint (eg, glove, sock), combined with intensive parent implemented practice focusing on active use of the impaired hand in a play-based context. In contrast, Baby BIM promotes active play requiring both hands in a play-based context. Both interventions will be delivered by parents at home with monthly home visits and interim telecommunication support by study therapists. Assessments will be conducted at study entry; at 6, 12 months ca immediately postintervention (primary outcome) and 24 months ca (retention). The primary outcome will be the Mini-Assisting Hand Assessment. Secondary outcomes include the Bayley Scale for Infant and Toddler Development (cognitive and motor domains) and the Hand Assessment of Infants. A subset of children will undertake MRI scans at 24 months ca to evaluate brain lesion severity and brain (re)organisation after intervention. Ethics and dissemination Full ethical approvals for this study have been obtained from the relevant sites. The findings will be disseminated in peer-reviewed publications. Trial registration number Australian and New Zealand Clinical Trials Registry: ACTRN12615000180516, Pre results.
    Keywords: Open access, Paediatrics
    Electronic ISSN: 2044-6055
    Topics: Medicine
    Published by BMJ Publishing
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