In:
British Journal of Ophthalmology, BMJ, Vol. 105, No. 5 ( 2021-05), p. 625-630
Abstract:
To evaluate the changes in corneal endothelium cell density (ECD) and the
correlated factors after Implantable Collamer Lens (ICL) V4c implantation. Methods In this retrospective, consecutive study, 48 eyes of 25 patients with
myopia who underwent ICL V4c implantation were enrolled. Patients were followed up for at least 4 years, during which manifest refraction, uncorrected distance
visual acuity, corrected distance visual acuity (CDVA), intraocular pressure, ECD, anterior chamber depth, anterior chamber volume (ACV), anterior chamber
angle (ACA), vault and distance from the corneal endothelium to the central ICL (C-ICL) were measured. Spearman’s correlation analysis was used to identify
variables correlated with changes in ECD, and generalised estimating equation model adjusting within-patient intereye correlations was used to predict
changes in ECD. Results All surgeries were performed safely with no complications during follow-up
(average 52±2.9 months). Safety and efficacy indices were 1.23±0.22 and 1.04±0.16, respectively. No eyes had decreased CDVA, and 67% gained one or more
lines. Further, 79% were within ±0.50 D, and 100% were within ±1.0 D of the attempted refraction. Additionally, a 4.03%±2.2% reduction in ECD compared with
the preoperative value was observed at the last follow-up visit. Changes in ECD were significantly correlated with vault, C-ICL, change in ACA and change in
ACV. Vault was the most significant factor for changes in ECD. Conclusions ICL V4c implantation is safe and effective for myopia correction. Anterior
segment biometric parameters including the vault, ACA and C-ICL may influence changes in ECD; specifically, the vault plays a major role.
Type of Medium:
Online Resource
ISSN:
0007-1161
,
1468-2079
DOI:
10.1136/bjophthalmol-2020-316144
Language:
English
Publisher:
BMJ
Publication Date:
2021
detail.hit.zdb_id:
1482974-5
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