In:
Thorax, BMJ, Vol. 75, No. 2 ( 2020-02), p. 172-175
Abstract:
We performed a prospective, observational, cohort study of children newly diagnosed with children’s interstitial lung disease (ChILD), with structured follow-up at 4, 8, 12 weeks and 6 and 12 months. 127 children, median age 0.9 (IQR 0.3–7.9) years had dyspnoea (68%, 69/102), tachypnoea (75%, 77/103) and low oxygen saturation (SpO 2 ) median 92% (IQR 88–96). Death (n=20, 16%) was the most common in those 〈 6 months of age with SpO 2 〈 94% and developmental/surfactant disorders. We report for the first time that ChILD survivors improved multiple clinical parameters within 8–12 weeks of diagnosis. These data can inform family discussions and support clinical trial measurements.
Type of Medium:
Online Resource
ISSN:
0040-6376
,
1468-3296
DOI:
10.1136/thoraxjnl-2019-213217
Language:
English
Publisher:
BMJ
Publication Date:
2020
detail.hit.zdb_id:
1481491-2
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