In:
Austin Journal of Clinical Pathology, Austin Publishing Group, Vol. 8, No. 1 ( 2021-06-30)
Abstract:
Age related changes in activity of hematopoietic progenitor cells led us to investigate the possibility that glucan supplementation might overcome this suppression. In our study, we focused on differences of these cells in young (8 weeks old) and old (18 months old) mice after supplementation of yeast-derived insoluble glucan. Our results showed significant differences in reconstitution ability of progenitor cells as well as changes in level of stromal cell-derived factor 1α between young and old mice exist and can be partly restored by glucan supplementation.
Type of Medium:
Online Resource
ISSN:
2381-9170
DOI:
10.26420/austinjclinpathol.2021.1071
Language:
Unknown
Publisher:
Austin Publishing Group
Publication Date:
2021
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