In:
Asian Journal of Chemistry, Asian Journal of Chemistry, Vol. 34, No. 11 ( 2022), p. 2849-2853
Abstract:
From the essential oil of the whole plant from Elsholtzia ciliata, obtained by hydrodistillation and
then using gas chromatography/mass spectrometry to analyze and identify 42 constituents, carveol (26.89%) and z-citral (29.35%) main contents (collected in the dry season time); and 46 constituents,
cis-ocimene (17.95%), carveol (14.84%), Z-citral (17.01%), isocaryophyllene (13.19%) and trans-caryophyllene (9.76%) as main contents (collected in the rainy season time). The major essential
oils in dry season exhibited good inhibition activity on the Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Candida albicans with MIC value of 200 μg/mL; exhibited weak cytotoxic
activity on the PC-3 line (IC50 66.34 μg/mL) and A549 line (IC50 93.11 μg/mL). The essential oils in rainy season exhibited good inhibition activity on the Escherichia coli, Bacillus subtillis and
Saccharomyces cerevisiae with MIC value of 200 μg/mL and Candida albicans with MIC value of 100 μg/mL; displayed good cytotoxic activity on the PC-3 line (IC50 30.62 μg/mL) and Hep-G2 line
(IC50 22.78 μg/mL), however have weak cytotoxic activity on the A549 line (IC50 85.35 μg/mL).
Type of Medium:
Online Resource
ISSN:
0975-427X
,
0970-7077
DOI:
10.14233/ajchem.2022.23821
Language:
English
Publisher:
Asian Journal of Chemistry
Publication Date:
2022
detail.hit.zdb_id:
3140213-6
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