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  • 1
    Electronic Resource
    Electronic Resource
    Endocrine Tissue Transplantation (1961)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 12 (1961), S. 271-280 
    Details
    ISSN: 0066-4219
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.me.12.020161.001415
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  • 2
    Electronic Resource
    Electronic Resource
    Spatial and temporal distributions of contaminant body burden and disease in Gulf of Mexico oyster populations: The role of local and large-scale climatic controls (1992)
    Springer
    Helgoland marine research 46 (1992), S. 201-235 
    Details
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract As part of NOAA's Status and Trends Program, oysters were sampled from 43 sites throughout the Gulf of Mexico from Brownsville, Texas, to the Florida Everglades from 1986 to 1989. Oysters were analysed for body burden of a suite of metals and petroleum aromatic hydrocarbons (PAHs), the prevalence and intensity of the oyster pathogen,Perkinsus marinus, and condition index. The contaminants fell into two groups based on the spatial distribution of body burden throughout the Gulf. Arsenic, selenium, mercury and cadmium were characterized by clinal reduction in similarity with distance reminiscent of that followed by mean monthly temperature and precipitation. Zinc, copper, PAHs and silver showed no consistent geographic trend. Within local regions, industrial and agricultural and use andP. marinus prevalence and infection intensity frequently correlated with body burden. Contaminants and biological attributes followed one of three temporal trends. Zinc, copper and PAHs showed concordant shifts over 4 years throughout the eastern and southern Gulf. Mercury and cadmium showed concordant shifts in the northwestern Gulf. Selenium, arsenic, length, condition index andP. marinus prevalence and infection intensity showed concordant shifts throughout most of the entire Gulf. Concordant shifts suggest that climatic factors, the El Niño/Southern Oscillation being one example, exert a strong influence on biological attributes and contaminant body burdens in the Gulf. Correlative factors are those that probably affect or indicate the rate of tissue turnover and the frequency of reproduction; namely, temperature, disease intensity, condition index and length.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02366055
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of sulfide and an increased food supply on the meiofauna and macrofauna at the East Flower Garden brine seep (1986)
    Springer
    Helgoland marine research 40 (1986), S. 57-82 
    Details
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A sulfurous brine seep at the East Flower Garden Bank, northwest Gulf of Mexico, produces conditions conducive to the growth of a luxuriant prokaryotic biota. Hydrodynamic cropping continually harvests this biota and distributes it to sandy-bottom and hard-bank benthic communities downstream of the seep. Consequently, both macro- and meiofaunal abundances are dramatically increased above the regional norm in parts of the seep system. When sulfide is present, the lower Bilaterian groups belonging to the meiofauna dominate the community; without sulfide, macrofaunal groups, particularly crustaceans, dominate the community. Outside the influence of the seep, meiofaunal copepods predominate. Changes in taxonomic composition and abundance indicate that the sandy-bottom benthos at 70–80 m depth at the East Flower Garden bank is foodlimited and that, under these conditions, meiofauna, particularly the higher Bilaterian groups, dominate the community numerically. Perhaps, under food-limiting conditions, meiofauna compete favorably with macrofauna for food.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01987289
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of various stimulus parameters on electrically-induced catecholamine secretion by thin slices of bovine adrenal medulla (1981)
    Springer
    Journal of neural transmission 50 (1981), S. 201-207 
    Details
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We examined the role of various stimulus parameters in electrically-induced catecholamine secretion by thin slices of bovine adrenal medulla. The stimulus parameters examined were voltage, duration, pulse width, and frequency for square-wave monophasic pulses. As each was examined it was held constant at a selected value for the evaluation of subsequent stimulus characteristics. For 16 mm2 tissue slices, catecholamine secretion was approximately linearly related to stimulus voltage over the range 20–80 volts, with a threshold of 20 V. Increasing the voltage beyond 80 V did not enhance secretion. Similarly, catecholamine secretion was dependent upon the frequency of stimulation. For stimuli delivered at 50 V for a 10-sec interval there was a four-fold increase in secretion over the frequency range 10–100/sec. Increasing pulse width at a constant voltage (50 V) over the range 0.4–2.0 msec resulted in a four-fold increase in catecholamine secretion. For pulses of 50 V, 50/sec and 0.8 msec pulse width, secretion was dependent upon the duration of the stimulus. Enhanced secretion was evident for times as short as 2 sec; between 5 and 15 sec of stimulation catecholamine secretion was linearly related to stimulus duration. Over the range 2–15 sec there was a five-fold enhancement of secretion. Electrically-induced catecholamine secretion by slices was markedly dependent upon stimulus parameters. In general, it was enhanced by increasing voltage, stimulus duration, pulse width and frequency. For most experiments a good choice of stimulus parameters appears to be 50 V, 10 sec duration, 0.8 msec pulse width delivered at a frequency of 50/sec. Maximizing all stimulus parameters resulted in a 17-fold enhancement of secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01249142
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  • 5
    Electronic Resource
    Electronic Resource
    Galactose inhibition of citric acid production from glucose by Aspergillus niger (1985)
    Springer
    Applied microbiology and biotechnology 22 (1985), S. 98-102 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Previous work in this laboratory has demonstrated that although Aspergillus niger can readily utilize galactose, no citric acid is produced from this carbon source (Hossain et al. 1984). Experiments were now conducted where galactose was added at various concentrations to synthetic growth medium containing glucose as carbon source, so that the effect of galactose on citric acid production from glucose could be observed. The results showed that the presence of galactose or a product of galactose metabolism caused inhibition of citric acid production, and also reduced the rate of glucose utilization. Enzyme analyses using mycelial cell-free extracts indicated that galactose interfered with the glucose-repression of the key enzyme 2-oxoglutarate dehydrogenase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00250027
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  • 6
    Electronic Resource
    Electronic Resource
    Survey for pesticides in wells associated with apple and peach orchards in West Virginia (1990)
    Springer
    Bulletin of environmental contamination and toxicology 44 (1990), S. 81-86 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01702365
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  • 7
    Electronic Resource
    Electronic Resource
    Gas chromatographic-mass spectrometric analysis of polycyclic aromatic hydrocarbon metabolites in Antarctic fish (Notothenia gibberifrons) injected with Diesel Fuel Arctic (1995)
    Springer
    Archives of environmental contamination and toxicology 29 (1995), S. 241-246 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Fish (Notothenia gibberifrons) collected in pristine Antarctic sites were injected with Diesel Fuel Arctic (DFA). Gas chromatography/mass spectrometry (GC/MS) was used to identify and quantify polycyclic aromatic hydrocarbon (PAH) metabolites obtained from hydrolyzed fish bile. The concentrations of naphthols (NPH), phenanthrenols (PHN), dibenzothiophenols (DBT), and total PAH metabolites (∑PAH) vary with time. The response curve (production of PAH metabolites vs. time) resembled a Sigmoid curve, with an initial low response at 24 h followed by a rapid rise in production of PAH metabolites (55.74 μg/g) 120 h after exposure to DFA. PAH metabolites identified include NPH, PHN, and DBT and their alkylated derivatives, reflecting the composition of the DFA to which the fish were exposed. The GC/MS technique is highly sensitive, particularly in the detection of multi-ring PAH metabolites. The results suggest that analysis of PAH metabolites is a valuable tool for environmental monitoring and assessment of exposure to petroleum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00212975
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  • 8
    Electronic Resource
    Electronic Resource
    The effect of methanol on citric acid production from galactose by Aspergillus niger (1986)
    Springer
    Applied microbiology and biotechnology 23 (1986), S. 203-205 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The effect of methanol on the ability of several strains of Aspergillus to produce citric acid from galactose has been investigated. In the absence of methanol, very little production (less than 1 g/l) was observed. In the presence of methanol (final concentration 1% v/v), however, citric acid production and yeilds were increased considerably. Strong relationships were observed between citric acid production and the activities of the enzymes 2-oxoglutarate dehydrogenase and pyruvate carboxylase in cell-free extracts. During citric acid production, in the presence of methanol, the activity of 2-oxoglutarate dehydrogenase was low and that of pyruvate carboxylase high. In the absence of methanol, where little citric acid was produced, the reverse was true. It is suggested that the presence of methanol may increase the permeability of the cell to citrate, and the cell responds to the diminished intracellular level by increasing production via repression of 2-oxoglutarate dehydrogenase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00261914
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  • 9
    Electronic Resource
    Electronic Resource
    Does chondroid chordoma exist? (1987)
    Springer
    Acta neuropathologica 72 (1987), S. 229-235 
    Details
    ISSN: 1432-0533
    Keywords: Chordoma ; Chondroid chordoma ; Chondrosarcoma ; Base of skull lesions ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The existence of chondroid chordoma (CC), initially described in 1973, has remained controversial. Since the antigenic profiles of both chordoma (CD) and cartilaginous (chondroid) lesions have been well characterized, we decided to study chondroid chordoma immunohistochemically. Our hypothesis was that chondroid chordoma should display a hybrid or mixed pattern of staining: chordomatous areas with an epithelial phenotype and cartilaginous areas with a mesenchymal (non-epithelial) phenotype. An analysis of CC (seven cases) was performed and compared with results obtained on notochord, cartilage, classic CD (18 cases), peripheral chondromas (two cases), and peripheral chondrosarcomas (CS, eight cases). Four epithelial markers were employed: MKER and AE-1 (both monoclonal antibodies to cytokeratin); PKER (a polyclonal antibody to cytokeratin); and, EMA (epithelial membrane antigen). In addition, selected cases were tested for the presence of neurofilament (NF) and glial fibrillary acidic protein (GFAP). All 18 CD's exhibited the expected epithelial immunophenotype — MKER+, AE-1+, PKER+, and EMA+ — a reaction pattern nearly identical to that found in fetal notochord. This reinforced the importance of the growth pattern in assessing the presence of chordomatous elements. All chondromas and CS's failed to express any of the epithelial markers studied and contained only S-100 immunoreactivity, like cartilage. Chondroid chordoma resembled cartilaginous tumors immunohistochemically; no mixed pattern with even focal epithelial marker reactivity was identified. All CC tested were also NF and GFAP negative. We conclude that CC either does not exist or is extremely rare and that these tumors are cartilaginous in nature. We propose abandoning the term chondroid chordoma and replacing it with “low grade chondrosarcoma”. Distinction from CD is still imperative due to the clear difference in natural history; we provide histological definitions and an immunophenotype to aid in this distinction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691094
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  • 10
    Electronic Resource
    Electronic Resource
    Magnetoresistivity of bismuth films in magnetic fields to 19 Tesla (1991)
    Springer
    Applied physics 52 (1991), S. 433-437 
    Details
    ISSN: 1432-0630
    Keywords: 75.30.Gw
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The longitudinal and transverse magnetoresistance to fields of 19 Tesla and 4.2 K has been measured for bismuth films ranging in thickness from 0.01 to 2 μm. We have observed a pronounced maximum in the longitudinal magnetoresistance which is thickness dependent. We compare these results with classical size effect theories for the longitudinal magnetoresistance in terms of magnetic-field-dependent electron scattering at grain and film boundaries. Measurements of the longitudinal magnetoresistance to 38 Tesla show a quenching of the classical size effect in the high field limit. This result strongly supports our analysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00323655
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