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  • 1
    Publication Date: 2011-06-22
    Description: Calcium (Ca) has declined to levels threatening aquatic biota in lakes on the eastern Canadian Shield. Predictive models for future changes in lake Ca are generally based on catchment-scale studies, but these models rarely account for unmeasured sources of Ca supply that are common in the nearshore areas of developed lakes. In this study we utilize up to 29 years of hydrological and water chemistry data for three lakes in central Ontario that differ in degree of human intervention to demonstrate that shoreline development may exert large effects on Ca mass balances. In the relative absence of shoreline development, Red Chalk Lake exhibited what we consider to be the normal response, a reduction in Ca load from the catchment over the last three decades, leading to a reduction in lake export and lake Ca concentration. Calcium load, export, and lake water Ca concentration also fell in Harp Lake, but less than in Red Chalk Lake, because Ca loads were elevated by human activities in Harp Lake's moderately developed shoreline area. By contrast, Dickie Lake experienced an exceptional change in Ca dynamics: both export and lake concentrations rose because of elevated load from the shoreline area linked to the use of dust suppressants on gravel roads. Reductions in both stream Ca concentration and flow volume have led to calcium decline in streams and lakes. Long-term soil acidification processes and climatic variability with its link to hydrology can explain the general pattern of Ca decline in lakes on the south-central Canadian Shield. However, given the widespread lakeshore development and use of dust suppressants on gravel roads, predictions of lake Ca levels need to take into account nearshore activities, especially those that augment rates of Ca supply.
    Print ISSN: 0043-1397
    Electronic ISSN: 1944-7973
    Topics: Architecture, Civil Engineering, Surveying , Geography
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  • 2
    Publication Date: 2018-01-18
    Description: Salinity is widely recognized as a dominant environmental variable in estuarine systems. However, drawing clear causal relationships between salinity and estuarine floral or faunal patterns of abundance, population status, or vigor is often confounded by the great spatial and temporal variation exhibited by salinity. Averages, or other statistics, over monthly, seasonal, or longer periods are often used, but may fail to capture patterns of ecological significance. This study introduces a novel approach to characterize estuarine salinity based on deriving events of specific magnitude and duration from a long-term record; events that are also amenable to analysis of the frequency that they reoccur. With sufficient point data for salinity over the spatial domain of an estuary, these variables can be mapped and contoured to reveal spatial patterns of potential ecological significance. Model-predicted salinity for a large estuary system of the Texas coast was used to develop and test these new techniques. While this system has great variation in salinity, both temporally and spatially, we find that this variability can be characterized into well-defined and reoccurring salinity-based events. Furthermore, the frequency of reoccurrence of those events over a long-term record reveals patterns not captured by more common techniques such as averaging over similar time frames. These novel techniques provide an integrated spatial-temporal approach to salinity pattern portrayal which may be useful for examining short-term (daily–monthly) estuary processes and longer-term (yearly–decadal) limits to estuary species distributions and habitat composition.
    Electronic ISSN: 1541-5856
    Topics: Biology , Geosciences
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  • 3
    Publication Date: 2015-07-30
    Description: ABSTRACT Crevasse splays are common geomorphological features in alluvial and deltaic floodplains. Although crevasse splays can develop into full avulsions, thereby transforming large areas of floodbasins, little is known about their sedimentary and geomorphological development at the decadal scale and their avulsion potential. We used aerial photography and lithological cross-sections to reconstruct crevasse-splay formation in the largely unmanaged floodplain of the Saskatchewan River in the Cumberland Marshes (Saskatchewan, Canada). Based on surface geomorphology and subsurface deposits, various stages of crevasse-splay development were described which were linked to both external forcing and internal morphodynamics. Initial splay deposition, following a levee breach during a large flood, occurred as a broad but relatively thin sandy sheet in a down-basin direction in the receiving backswamp area. In a next phase, these primary crevasse-splay deposits blocked local down-basin flow, thereby forcing the crevasse-splay channel in a direction perpendicular to the parent channel and original floodbasin gradient. This created an asymmetrical splay sequence composition, which differs in appearance from more commonly observed dendritic crevasse splays. It is concluded that sedimentation patterns in the splay have been influenced by inherited effects of previously formed deposits. Feedbacks of the original floodbasin gradient and earlier stages of splay formation are suggested as prominent mechanisms in creating the current morphology, orientation, and architecture of its deposits. This article is protected by copyright. All rights reserved.
    Print ISSN: 0197-9337
    Electronic ISSN: 1096-9837
    Topics: Geography , Geosciences
    Published by Wiley-Blackwell
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  • 4
    Publication Date: 2014-03-30
    Description: The kidney is a model developmental paradigm of vertebrate organogenesis. As in many other organs, kidney development involves reciprocal inductive tissue interactions between multiple cell lineages. The most well defined of these interactions occurs between the ureteric bud and the nephrogenic mesenchyme. A population of mesenchymal cells distinct from nephrogenic precursors and termed stromal cells, have been relatively understudied. Yet existing knowledge indicates that stromal cells are critical regulators in the normal and diseased kidney. This commentary reviews current knowledge regarding the origin and functional roles of the stromal cell population during kidney development. Gaps in our current understanding of renal stromal cells and future directions needed to advance this expanding field of study are highlighted. Developmental Dynamics, 2014. © 2014 Wiley Periodicals, Inc.
    Electronic ISSN: 1097-0177
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 5
    Publication Date: 2012-08-04
    Description: A large-scale geographical study of the ice pack in the seasonal ice zone of the Weddell Sea, Antarctica, took place from September to October 2006. Sea ice brines with a salinity greater than 58 and temperature lower than −3.6°C were sampled from 22 ice stations. The brines had large deficits in total alkalinity and in the concentrations of the major dissolved macronutrients (total dissolved inorganic carbon, nitrate, and soluble reactive phosphorus) relative to their concentrations in the surface oceanic water and conservative behavior during seawater freezing. The concentration deficits were related to the dissolved inorganic carbon-consuming processes of photosynthesis, CaCO3 precipitation, and CO2 degassing. The largest concentration deficits in total dissolved inorganic carbon were found to be associated with CaCO3 precipitation and CO2 degassing, because the magnitude of the photosynthesis-induced concentration deficit in total dissolved inorganic carbon is controlled by the size of the inorganic nutrient pool, which can be limited in sea ice by its openness to exchange with the surrounding oceanic water.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
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  • 6
    Publication Date: 2014-09-28
    Description: Urea is a common fertilizer in delayed-flood rice production in the United States, and its use worldwide has increased dramatically in recent decades. This study aimed to directly quantify urea-N persistence in floodwater and soil used for rice production. We conducted a set of three laboratory experiments to investigate urea-N presence in the floodwater and soil. Untreated urea was applied to dry or wet soil and flooded immediately or urea treated with the urease inhibitor N-(n-butyl)-thiophosphoric triamide (NBPT), or untreated urea was applied to dry soil and flooded after a 5-day delay. Urea-N was analysed colorimetrically (using the microplate-adapted, diacetyl monoxime method) in the floodwater, and at 2-cm intervals in soil after 10-cm long, silt-loam soil columns were flooded for 12, 24, 48 and 96 h. The only management practice that led to insignificant urea-N concentrations in floodwaters was the application of urea followed by a 5-day delay before flooding. Urea-N can persist in floodwaters for an estimated 98 and 120 h after immediately flooding dry-soil-applied or wet-soil-applied untreated urea, respectively. Urea-N concentrations in floodwaters were up to 33 times less when dry-soil-applied than wet-soil-applied. Average NBPT-treated urea-N concentrations in soil ranged up to 63 mg/kg after 24 h of flooding and were 〈1 mg/kg after 96 h of flooding. The 5-day delay resulted in ≤1 mg urea-N/kg soil when untreated urea was applied. Generally, the threat of N entering adjacent waterways in the form of urea is likely to be limited because of its short-term persistence (≤120 h) in rice floodwater.
    Print ISSN: 0266-0032
    Electronic ISSN: 1475-2743
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Published by Wiley-Blackwell
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  • 7
    Publication Date: 2013-10-02
    Description: ABSTRACT The rationale for screening inflammatory serum biomarkers of the hepatic vein pressure gradient (HVPG) is based on the fact that portal hypertension is pathogenically related to liver injury and fibrosis, and that in turn these are associated with the activation of inflammatory pathways. This was a nested cohort study in the setting of a randomized, clinical trial to assess the development of gastroesophageal varices (GEV) ( N Engl J Med. 353:2254; 2005 ). Patients had cirrhosis and portal hypertension but did not have GEV. A total of 90 patients that had baseline day-1 sera available were enrolled into the present study. The objective of this study was to determine whether inflammatory biomarkers in conjunction with clinical parameters could be used to develop a predictive paradigm for HVPG. The correlations between HVPG and IL-1β ( P= 0.0052); IL-1R-alpha ( P= 0.0085); Fas-R ( P= 0.0354) and serum VCAM-1 ( P= 0.0007) were highly significant. By using multivariate logistic regression analysis and selected parameters (TGFβ; HSP-70; at-risk alcohol use; and Child-Pugh B score) we could exclude HVPG equal or 〉 12 mmHg with 86 % accuracy ( 95% Confidence Interval; 67.78 to 96.16 %) and the sensitivity was 87.01 % (95% Confidence Interval; 69.68 to 96.34 %). Therefore, the composite test could identify 86 % of compensated cirrhotic patients with HVPG below 12 mmHg and prevent unnecessary esophagogastroduodenoscopy with its associated morbidity and costs in these patients. Our diagnostic test was not efficient in predicting HVPG equal or 〉12 mmHg. Conclusion : A blood test for HVPG could be performed in cirrhotic patients to prevent unnecessary esophagogastroduodenoscopy. (H epatology 2013)
    Print ISSN: 0270-9139
    Electronic ISSN: 1527-3350
    Topics: Medicine
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  • 8
    Publication Date: 2017-06-01
    Description: BACKGROUND: Deficiency of Suppressor of Fused (SuFu), an intracellular mediator of Hedgehog signaling, in the murine mid-hindbrain disrupts cerebellar morphogenesis and cell differentiation in a manner that is rescued by constitutive expression of GLI3 transcriptional repressor (GLI3R). Here, we determined SuFu functions in cerebellar radial precursors following the stage of mid-hindbrain specification using a Blbp-Cre transgene. RESULTS: SuFu- deficient cerebella were severely dysplastic, and characterized by laminar disorganization, and delayed differentiation of ventricular zone-derived precursors. In vitro analysis of cerebellar precursors isolated from control and mutant mice demonstrated an increased proportion of radial glial precursors versus Tuj1- positive neurons in mutant cultures. Abnormal cell differentiation in SuFu-deficient precursors was rescued by a constitutively expressed GLI3R knock-in allele, albeit with variable penetrance. Using RNA expression analysis in control and SuFu- deficient cerebellar anlage, we identified up-regulation of Fgf15 in mutant tissue. Strikingly, exogenous hFGF19, a mFGF15 ortholog, inhibited neuronal differentiation in cultures of wild-type cerebellar precursors. Moreover, siRNA-mediated knockdown of Fgf15 in SuFu -deficient cerebellar precursors rescued their delayed differentiation to neurons. CONCLUSIONS: Together, our results show that SuFu promotes cerebellar radial precursor differentiation to neurons. SuFu function is mediated in part by GLI3R and down-regulation of Fgf15 expression. This article is protected by copyright. All rights reserved.
    Electronic ISSN: 1097-0177
    Topics: Medicine
    Published by Wiley-Blackwell
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  • 9
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Earth and Planetary Sciences 32 (2004), S. 257-285 
    ISSN: 0084-6597
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Geosciences , Physics
    Notes: Avulsion is the natural process by which flow diverts out of an established river channel into a new permanent course on the adjacent floodplain. Avulsions are primarily features of aggrading floodplains. Their recurrence interval varies widely among the few modern rivers for which such data exist, ranging from as low as 28 years for the Kosi River (India) to up to 1400 years for the Mississippi. Avulsions cause loss of life, property damage, destabilization of shipping and irrigation channels, and even coastal erosion as sediment is temporarily sequestered on the floodplain. They are also the main process that builds alluvial stratigraphy. Their causes remain relatively unknown, but stability analyses of bifurcating channels suggest that thresholds in the relative energy slope and Shields parameter of the bifurcating channel system are key factors.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 37 (1986), S. 215-224 
    ISSN: 0066-4219
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine
    Type of Medium: Electronic Resource
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