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  • 1
    ISSN: 1572-8854
    Keywords: Citric acid ; citrate complex ; oxovanadium(V) complex ; vanadate ; molecular structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Potassium and ammonium dimeric (citrato)dioxovanadium(V) hydrate K2[VO2(H2cit)]2·4H2O1 and (NH4)2[VO2(H2cit)]2·2H2O2 (H4cit=citric acid) have been prepared and characterized by X-ray structure analyses. Vanadate1 crystallizes in the monoclinic space groupP21/n (No. 14) with unit cell parameters:a=9.304(2),b=11.756(2),c=11.911(2)Å, β=111.72(3)°, andD c=1.911 g/cm3,Z=2; Vanadate2 also crystallizes in the monoclinic space groupP21/n with unit cell parameters:a=9.719(2),b=11.111(3),c=11.294(2)Å, β=109.03(2)°, andD c=1.781 g/cm3,Z=2. Each dimer contains a centro-symmetric planar four-member V2O2 ring with two exocyclic citrate entities coordinated by the oxygen atoms of the hydroxy-and α-carboxylate ligands, while the other two β-carboxylate groups remain uncomplexed. Principal dimensions of the V−O bonds are 1.986(4)av (hydroxy) and 1.980(3)Å(α-carboxyl) for vanadate1, 1.988(2)av (hydroxy) and 1.974(3)Å(α-carboxyl) for vanadate2.
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  • 2
    ISSN: 1432-0851
    Keywords: Key words Interleukin-2 receptor ; Protein kinase C ; Acute lymphoblastic leukemia ; Immunosuppression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Peripheral blood lymphocytes obtained from children with acute lymphoblastic leukemia (ALL) at onset were studied for the expression of interleukin-2 (IL-2) receptor α-chain (CD25) by two-color flow-cytometric analysis. Stimulated with anti-CD3 monoclonal antibody (mAb) alone, CD25 expression was significantly suppressed in CD4+ T cells from 27 of 48 (56.3%) cases and in CD8+ T cells from 29 of 48 (60.4%) cases. When stimulated with anti-CD3 mAb plus phorbol 12-myristate 13-acetate (PMA), CD25 expression was clearly restored in certain cases of ALL. When PMA plus ionomycin were used for stimulation of T cells, CD25 was inducible in a majority of cases. Interestingly CD25 expression upon anti-CD3 mAb stimulation was recovered after complete remission had been achieved. These observations suggest the presence in ALL children at onset of an in vitro defect in the signal transduction pathway of the T-cell-receptor/CD3 complex, resulting in inefficient CD25 expression. However, immune-staining analysis indicated that protein kinase C was normally translocated from the cytosol fraction to the cell membrane fraction. The mobilization of cytoplasmic free calcium is also normal.
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  • 3
    ISSN: 1432-0851
    Keywords: Immunosuppression ; Chemotherapy ; Acute lymphoblastic leukemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present study was designed to evaluate the chemotherapy-induced cellular immunosuppression in 20 children with acute lymphoblastic leukemia (ALL) in remission and receiving maintenance chemotherapy. Peripheral blood was serially obtained from leukemic children during vincristine/cyclophosphamide/6-mercaptopurine/prednisone combined consolidation chemotherapy. The mean absolute number of peripheral blood lymphocytes as well as the mean absolute numbers of lymphocyte subsets (T cells, T cell subsets, B cells, and natural killer cells) from leukemic children before consolidation chemotherapy were all significantly lower than in control subjects; however, the percentages of lymphocyte subsets were similar in both groups. After consolidation chemotherapy, the percentages of CD4+ T lymphocytes and natural killer (NK) cells were significantly decreased and the percentages of monocytes and CD8+ T lymphocytes were significantly increased. Phytohemagglutinin- and 12-O-tetradecanoylphorbol-13-acetate-induced production of interleukin-2 (IL-2) and NK-cell-mediated cytotoxic activity by peripheral blood mononuclear cells (PBMC) were also substantially decreased in the post-therapy groups. NK activity correlated with the percentage of NK cells in PBMC. In contrast, OK432-induced production of tumor necrosis factor α (TNFα) and killer activity against NK-resistant target cells were significantly increased after therapy as compared with the pre-therapy and control groups. TNFα production correlated with the percentage of monocytes in PBMC. These results demonstrate that substantial quantitative and qualitative chemotherapy-induced abnormalities of the cellular immune system are present in the majority of patients treated with ALL. It is also suggested that the increased TNFα production by monocytes and the appearance of potent killing activity against NK-resistant targets might compensate for the defects of IL-2 production and NK activity during intensive consolidation chemotherapy.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of applied phycology 8 (1996), S. 535-543 
    ISSN: 1573-5176
    Keywords: Ascophyllum nodosum ; betaines ; commercial seaweed extract ; leaf chlorophyll ; soil application
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Application to the soil of an aqueous alkaline extract ofAscophyllum nodosum resulted in higher concentrations of chlorophyll in the leaves of treated plants in comparison to control plants treated with an equivalent volume of water. Positive results were obtained with all species tested (tomato, dwarf French bean, wheat, barley, maize). When the seaweed extract was applied as a foliar spray, similar effects on leaf chlorophyll contents were obtained, except in the case of dwarf French bean plants, for which no significant difference was recorded between test and control plants. When the betaines present in the seaweed extract were applied as a mixture in the same concentrations as those in the diluted seaweed extract (γ-aminobutyric acid betaine 0.96 mg L−1, δ-aminovaleric acid betaine 0.43 mg L−1, glycinebetaine 0.34 mg L−1), very similar leaf chlorophyll levels were recorded for the seaweed extract and betaine treated plants. This suggests strongly that the enhanced leaf chlorophyll content of plants treated with seaweed extract is dependent on the betaines present.
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  • 5
    ISSN: 1573-5044
    Keywords: paclitaxel ; review ; taxoid ; Taxus sp. ; tissue culture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The literature concerning the tissue culture of Taxus sp. as an alternative source for taxoid production is reviewed. The aim of this review is to summarize and discuss the progress achieved with the approaches and methods used for the establishment of various Taxus culture systems, the methods used for the evaluation of taxoid production, the multiple factors which control taxoid production and the feasibility of the in vitro production of taxoids on a commercial scale.
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  • 6
    Publication Date: 2015-08-15
    Description: Author(s): Yu-Qian Zhou, Hong-Wei Li, Yu-Kun Wang, Dan-Dan Li, Fei Gao, and Qiao-Yan Wen By proposing device-independent protocols, Pironio et al. [ Nature (London) 464 , 1021 (2010) ] and Colbeck et al. [ Nat. Phys. 8 , 450 (2012) ] proved that new randomness can be generated by using perfectly free random sources or partially free ones as seed. Subsequently, Li et al. [ Phys. Rev. A 84 , 0343… [Phys. Rev. A 92, 022331] Published Thu Aug 13, 2015
    Keywords: Quantum information
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
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  • 7
    Publication Date: 2015-07-05
    Description: Author(s): Xia Wu, Ying-hui Yang, Yu-kun Wang, Qiao-yan Wen, Su-juan Qin, and Fei Gao The determination of many special types of quantum states has been studied thoroughly, such as the generalized | GHZ 〉 states, stochastic local operations and classical communication equivalent | W 〉 states, and Dicke states. In this paper, we study another special entanglement state, that is, stabilize… [Phys. Rev. A 92, 012305] Published Thu Jul 02, 2015
    Keywords: Quantum information
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
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  • 8
    Publication Date: 2015-07-30
    Description: Author(s): Zhi-Chao Zhang, Fei Gao, Su-Juan Qin, Ying-Hui Yang, and Qiao-Yan Wen In this paper, we mainly study the local indistinguishability of mutually orthogonal product basis quantum states in d ⊗ d . In 3 ⊗ 3 , Bennett et al. [ Phys. Rev. A 59 , 1070 (1999) ] presented nine orthogonal product basis quantum states which cannot be distinguished by local operations and classical comm… [Phys. Rev. A 92, 012332] Published Wed Jul 29, 2015
    Keywords: Quantum information
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
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  • 9
    Publication Date: 2015-11-20
    Description: Author(s): Yu-Kun Wang, Su-Juan Qin, Xia Wu, Fei Gao, and Qiao-Yan Wen Quantum systems can be used to certify the existence of true randomness in nature, and semi-device-independent (SDI) randomness expansion has been used to achieve this goal under the prepare-measure configuration. Usually, randomness is certified with the degree of violation of some inequalities. Ho… [Phys. Rev. A 92, 052321] Published Thu Nov 19, 2015
    Keywords: Quantum information
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
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  • 10
    Publication Date: 2015-12-02
    Description: Author(s): Xia Wu, Ying-hui Yang, Qiao-yan Wen, Su-juan Qin, and Fei Gao It has been proven by Rana et al. that the n -qubit generic Dicke states | GD ( n , ℓ ) 〉 are uniquely determined, among arbitrary states, by their ( ℓ + 1 ) -partite reduced density matrices, and ( n − 1 ℓ ) number of them which have one party common to all are sufficient. We show that among arbitrary states, Dicke-… [Phys. Rev. A 92, 052338] Published Mon Nov 30, 2015
    Keywords: Quantum information
    Print ISSN: 1050-2947
    Electronic ISSN: 1094-1622
    Topics: Physics
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