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  • American Diabetes Association  (2)
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  • American Diabetes Association  (2)
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  • 1
    Online Resource
    Online Resource
    Blood Ketone Response to Norepinephrine-induced Free Fatty Acid Elevation in Diabetes
    American Diabetes Association ; 1964
    In:  Diabetes Vol. 13, No. 5 ( 1964-09-01), p. 518-526
    Details
    In: Diabetes, American Diabetes Association, Vol. 13, No. 5 ( 1964-09-01), p. 518-526
    Abstract: 1. During ninety-minute norepinephrine infusions, blood free fatty acid and ketone responses of Japanese nondiabetic and diabetic subjects were determined. Nonobese diabetic subjects with and without fasting hyperglycemia demonstrated significantly greater blood ketone elevations than nondiabetics. 2. An inverse correlation between obesity and blood ketone response to norepinephrine was observed in diabetics. This correlation could not be attributed to varying degrees of fasting hyperglycemia or free fatty acid elevation. 3. Nonobese diabetics with mild fasting hyperglycemia (90 to 150 mg. per 100 ml.) exhibited an unexpected greater increase in blood ketones than nonobese diabetics with moderate fasting hyperglycemia (150 to 250 mg. per 100 ml.). Differences in free fatty acid elevations were not responsible for this apparent paradox. 4. The magnitude of the hyperketonemic response, though dependent on free fatty acid elevation, seemed more sensitive to the degree of obesity and the fasting blood glucose level. Fractional ketone body measurements indicated that the blood ketone elevations were predominantly due to fihydroxybutyric acid increases.
    Type of Medium: Online Resource
    ISSN: 0012-1797 , 1939-327X
    URL: Article
    DOI: 10.2337/diab.13.5.518
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 1964
    detail.hit.zdb_id: 1501252-9
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    Online Resource
  • 2
    Online Resource
    Online Resource
    The Clinical Features of Diabetes Mellitus in Japan as Observed in a Hospital Outpatient Clinic
    American Diabetes Association ; 1964
    In:  Diabetes Vol. 13, No. 5 ( 1964-09-01), p. 485-491
    Details
    In: Diabetes, American Diabetes Association, Vol. 13, No. 5 ( 1964-09-01), p. 485-491
    Abstract: A University diabetes clinic in Japan was characterized in terms of age, age at “onset,” sex ratio, microangiopathies, neuropathy, atherosclerotic complications, weight, heredity and diet. The findings in this clinic, along with those from other diabetes clinics in Japan, were compared with studies on Western diabetics. The similarities between the two diabetic populations in clinics far outnumbered the dissimilarities. However, diabetes mellitus in Japanese diabetes clinics is distinguished by the infrequent occurrence of juvenile diabetes and ketosis, relative lack of atherosclerotic complications and reversal of the sex ratio.
    Type of Medium: Online Resource
    ISSN: 0012-1797 , 1939-327X
    URL: Article
    DOI: 10.2337/diab.13.5.485
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 1964
    detail.hit.zdb_id: 1501252-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
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