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  • Springer  (438)
  • American Chemical Society (ACS)  (40)
  • 1
    ISSN: 1430-3418
    Keywords: Aldose reductase ; Aminoguanidine ; Ascorbic acid ; Kidney ; Sorbinil ; Sorbitol ; Zopolrestat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Aldose reductase inhibitors (ARI) have been developed to reduce the conversion of high glucose levels to sorbitol, an important renal osmolyte that may rise to damaging levels in many tissues during diabetic hyperglycemia. Ascorbic acid (AA) and aminoguanidine (AMG) have also been reported to reduce sorbitol levels in diabetes: AMG in rat kidney, and AA in guinea pig lens and human erythrocytes. We tested the effects of AMG, AA, and Pfizer’s sorbinil and zopolrestat for 48 h on primary rat renal cell cultures, established from renal inner medullas of male Wistar rats 8–12 weeks old. Osmolyte contents in scraped cells were analysed by HPLC: 100 µM sorbinil and 20 µM zopolrestat decreased sorbitol levels (P〈0.05 and P〈0.001, respectively), and increased the content of another osmolyte, betaine (P〈0.01 and 〈0.01, respectively). The quantity of ATP in cells was unchanged, suggesting no short-term problems. In contrast, 10 mM AMG and 10 mM AA had no effect on sorbitol contents (in contrast to some previous studies). We then tested aldose reductase (AR) activity in crude homogenates of rat lens and renal inner medulla, with glyceraldehyde substrate. For both tissues, 5 µM zopolrestat inhibited AR activity by 92–94% (P〈0.002); 10 mM AA by 16–20% (P〈0.02); and 10 mM aminoguanidine by 22–24% (P〈0.03). We conclude that AMG and AA are not readily usable as inhibitors of renal AR.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 115 (1977), S. 1167-1186 
    ISSN: 1420-9136
    Keywords: Monsoon ; Effect on angular momentum, effect on kinetic energy ; Tropical general circulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The balance conditions of relative angular momentum and time-mean kinetic energy and their annual variations are studied for the Northern Hemisphere tropical belt. The belt is divided into two roughly equal size parts, the monsoon and the extramonsoon regions. The data used consist of all available daily rawinsonde reports from the world areological network for the two 5-year periods 1958–63 and 1968–73. In winter, the trade winds in the monsoon and extramonsoon regions are both sources of westerly relative angular momentum for the middle latitude circulation. However, it is found that the angular momentum gained in the extramonsoon region of the Tropics is mostly destroyed by a net southward flow of mass in that region, and becomes regenerated in the monsoon region by a net northward flow of mass there. This excess of angular momentum together with the angular momentum picked up locally in the monsoon region is almost all exported across its northern boundary. It is further found that in winter the Tropics are also an important source of mean kinetic energy for middle latitudes. Again almost all export of kinetic energy was found to take place across the northern boundary of the monsoon sector. Most of this energy must be generated through the pressure gradient term inside the monsoon region itself, the transformation from transient eddy kinetic energy being very small. The proper evaluation of the pressure gradient appears to be the main stumbling block in the present study, preventing us from estimating the generation and thereby, as a residual, the frictional dissipation in the two regions. In summer, the extramonsoon region remains a source of angular momentum, but the monsoon region with its surface westerlies acts as a sink, leading to a sharp reduction (and even a midsummer reversal) of the export into middle latitudes. Also the export of mean kinetic energy almost vanishes in summer, except for a small southward transfer across the equator. The calculations for two 5-year periods give very similar estimates and thereby show the reliability of the results.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 66 (1967), S. 133-139 
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Description / Table of Contents: Summary The results of an investigation of the deposition of nuclear weapon debris from the third Chinese test explosion are discussed.t −(1+x )-curves were measured and the values of the parameterx are presented. The dry and precipitation fallout samples and a hot particle were gammaspectrometrically examined. Fractionation phenomena were studied.
    Notes: Zusammenfassung Am 9. Mai wurde der dritte chinesische Kernwaffenversuch durchgeführt. Als Folge konnte etwa vierzehn Tage nach dem Explosionszeitpunkt in Stuttgart-Hohenheim eine deutliche Zunahme des radioaktiven Befalls festgestellt werden. Für die gewonneuen Niederschlags-, Staub- und Luftfilterproben, sowie für ein Heisses Teilchen wurdent −(1+x )-Kurven gemessen, diex-Werte bestimmt und gammaspektrometrisch die Nuklidzusammensetzung untersucht. An den aufgefundenen Nukliddiskriminierungen ist bemerkenswert, dass das Heisse Teilchen eine deutliche95Zr-95 Nb-Anreicherung aufwies.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Pure and applied geophysics 88 (1971), S. 35-43 
    ISSN: 1420-9136
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Summary The transmission of transverse surface waves in piezoelectric (622) crystal class has been studied in four cases. In the first case, a thin piezoelectric layer is resting on a deep elastic layer whereas in the second case, both the layers are considered piezoelectric with different materials. In the third case, a piezoelectric stratum is bounded on both sides by deep elastic layers whereas, in the fourth case, the upper and lower elastic layers are replaced by piezoelectric layers of different materials. The wave velocity equations are obtained for all cases.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Discrete & computational geometry 5 (1990), S. 263-288 
    ISSN: 1432-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract A hyperplane arrangement is a finite set of hyperplanes through the origin in a finite-dimensional real vector space. Such an arrangement divides the vector space into a finite set of regions. Every such region determines a partial order on the set of all regions in which these are ordered according to their combinatorial distance from the fixed base region. We show that the base region is simplicial whenever the poset of regions is a lattice and that conversely this condition is sufficient for the lattice property for three-dimensional arrangements, but not in higher dimensions. For simplicial arrangements, the poset of regions is always a lattice. In the case of supersolvable arrangements (arrangements for which the lattice of intersections of hyperplanes is supersolvable), the poset of regions is a lattice if the base region is suitably chosen. We describe the geometric structure of such arrangements and derive an expression for the rank-generating function similar to a known one for Coxeter arrangements. For arrangements with a lattice of regions we give a geometric interpretation of the lattice property in terms of a closure operator defined on the set of hyperplanes. The results generalize to oriented matroids. We show that the adjacency graph (and poset of regions) of an arrangement determines the associated oriented matroid and hence in particular the lattice of intersections.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Discrete & computational geometry 8 (1992), S. 209-213 
    ISSN: 1432-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract In this paper we compute in closed form the average number ofk-sets of an allowable sequence.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Abdominal imaging 2 (1977), S. 109-111 
    ISSN: 1432-0509
    Keywords: Celiac disease ; Spontaneous pneumoperitoneum ; Plenumatosis cystoides intestinalis ; Obstructing intussusception
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Spontaneous pneumoperitoneum and pneumatosis cystoides intestinalis have been undescribed complications of celiac disease. In the case reported, small bowel gas cysts caused an obstructing intussusception. The etiology of the pneumatosis cystoides intestinalis is discussed.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0509
    Keywords: Colon, lymphoid hyperplasia ; Granulomatous colitis ; Sarcoidosis ; Infectious mononucleosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The radiographic pattern of nodular lymphoid hyperplasia, perhaps better called the lymphoid follicular pattern, has variously been described as an indication of disease and as a normal variant in the adult, with current opinion favoring the latter. We report 3 cases wherein this pattern resulted from definite pathologic processes: sarcoidosis, infectious mononucleosis, and Crohn's disease. Although usually of no pathological significance, the benign follicular pattern may reflect a variety of diseases.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0509
    Keywords: Colitis, ulcerative ; Colitis, complications ; Colon, tumor ; Radiography, magnification technique
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Epithelial dysplasia occurring in long-standing ulcerative colitis is a precancerous lesion. Macroscopically it has a nodular or villous appearance or may be indistinguishable from the surrounding mucosa. An investigation into the radiological diagnosis of dysplasia, using in vivo and in vitro doublecontrast examinations with magnification radiographic studies, correlated with the histological analysis, has been made in four patients. Characteristic radiological abnormalities have been identified in the areas of the mucosa associated with histologically proven dysplasia. These appearances include nodularity and irregular areas with sharply angulated edges which may represent enlarged areae colonicae. The demonstration of these changes is an indication for endoscopie examination and biopsy of the suspicious area.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Manuscripta mathematica 11 (1974), S. 273-282 
    ISSN: 1432-1785
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract Earlier qualitative theorems are used to study the structure of the set of solutions of a family of ordinary differential equations. In particular lower bounds for the number of solutions having different numbers of nodes is obtained.
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