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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 52 (1980), S. 1310-1312 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 9 (1930), S. 1618-1618 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 151 (1930), S. 1-11 
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 125 (1927), S. 358-380 
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 114 (1995), S. 100-102 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirty-three patients with fractures of the thoracolumbar spine were treated by fusion and Harrington instrumentation after early reduction and stabilisation by postural reduction or halo-bifemoral traction. The rod-long-fuse-short technique was used. Postoperatively, all patients were mobilised with an external support. The mean follow-up was 6 years (range 1–13 years). Twenty-eight patients were pain-free, three patients needed sporadic pain medication. One patient was not working due to pain in his leg. One patient had constant pain. Twenty-three patients returned to work. The mean kyphosis increased from 8° postoperatively to 13° at follow-up.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 112 (1993), S. 157-158 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two patients with sleeve fractures of the patella and tibial tuberosity respectively are described. Our two cases demonstrate that the diagnosis can be difficult; patella alta and ossification in the patellar tendon are complications of conservative treatment. Early diagnosis and operative reduction and fixation are mandatory.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 45 (1996), S. 519-523 
    ISSN: 1420-908X
    Keywords: Leukotrienes ; Streptozotocin ; Estradiol ; Lipopolysaccharide ; Galactosamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The acute phase response to chemically-induced organ damage involves inflammation and the production of leukotrienes. The liver ordinarily takes up, metabolizes and excretes into bile cysteinyl leukotrienes, but the effect of hepatic injury on these processes is unknown. The hepatic uptake and biliary excretion of LTC4 was studied in male Sprague-Dawley rats after exposure to either streptozotocin (45 mg/kg iv 30 days before experimentation), estradiol-17 β-valerate (1mg/kg sc once a week for 3 weeks) or lipopolysaccharide/d-galactosamine (33 μg/kg ip; 300 mg/kg ip at 6 h and 3 h, respectively, before experimentation). Acute liver injury is produced by these treatment paradigms. Glucose concentrations and activities of several marker enzymes in plasma were measured to demonstrate hepatic injury. Biliary excretion of3H-LTC4 was similar to normal control rats in the three types of acute liver injury. Bile flow rates after3H-LTC4 injection were reduced in lipopolysaccharide-pretreated rats and increased in estradiol-treated animals. Total biliary excretion of leukotrienes was not altered in any disease group. Thus, these models of acute hepatic injury do not appear to influence the hepatobiliary clearance of leukotrienes.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 342 (1973), S. 255-260 
    ISSN: 1432-2013
    Keywords: Skin ; Elasticity ; Aging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Measurements of physical properties of the intact human skin are described. An analysis of the measurements yields parameters that characterize elastic, visco-elastic and plastic properties. Between 6 and 61 years the elastic component of the extensibility of the skin under torsional conditions increases with age. The visco-elastic and plastic components are constant up to an age of fourty; at higher ages they show a small tendency to increase. Moduli of elasticity of the intact human skin derived from the torsion measurements yield values between about 2×104 N/m2 and 105 N/m2, the highest values corresponding to the youngest age. From these values the moduli of elasticity of the elastic fibres in the living skin are estimated between about 2×106 N/m2 and 107 N/m2.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The astronomy and astrophysics review 2 (1990), S. 1-28 
    ISSN: 1432-0754
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Neutral hydrogen line observations of the extended rotation curves of spiral galaxies imply that there exist significant discrepancies between the luminous and dynamical mass beyond the bright optical discs. This means either that galaxies contain significant quantities of non-luminous matter (matter with a mass-to-light ratio very much higher than that of ordinary stars), or that the law of gravity on the scale of galaxies is not the usual Newtonian inverse square law. Attempts to account for the observed discrepancy in the context of these two explanations are reviewed here with emphasis given to the second and less conventional alternative. It is argued that the standard picture of spiral galaxy halo and disc formation in the context of cold dark matter cannot account for the observed systematics of the discrepancy — notably rotation curves which are seen to be flat and featureless from the bright inner regions where the visible matter dominates the dynamics (in some cases overwhelmingly) to the outer regions where the dark halo dominates. It is demonstrated that in those galaxies with well-observed rotation curves, the discrepancy apparently appears below a critical acceleration. Any dark matter explanation of the discrepancy must account for this fact. Moreover, this would also eliminate empirically motivated modifications of Newton's law in which the deviation from 1/r occurs beyond a fundamental length scale. The suggestion by Milgrom in which the force law becomes essentially 1/r below a critical acceleration (MOND) can account for most of the observed systematics of galaxy rotation curves and, significantly, leads to the observed luminosity-velocity relationship in spiral galaxies (the Tully-Fisher law). Generally covariant theories of gravity which predict this phenomenology in the weak-field limit are described. Although there is not yet a theory which obviously meets all of the requirements for a physically viable alternative to dark matter, a generalized scalar-tensor theory of the form suggested by Bekenstein (phase coupling gravitation) is the currently leading candidate and has the advantage of being testable locally.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We investigated the influence of bacteria and metazooplankton on the production of dimethylsulfoniopropionate (DMSP) and dimethylsulfide (DMS) during blooms of Emiliania huxleyi (Lohmann) Hay and Mohler in seawater mesocosms. The phytoplankton succession was marked by the rapid collapse of an initial Skeletonema costatum (Greville) Cleve bloom followed by a small E. huxleyi bloom. The collapse of the diatom bloom was accompanied by an increase in concentrations of dissolved DMSP (DMSPd) and bacterial abundance and activity (as determined by the thymidine incorporation technique). The increase in bacterial activity was followed by a rapid decrease in DMSPd concentrations which remained low for the rest of the experiment, even during the subsequent collapse of the E. huxleyi blooms. The absence of DMSPd and DMS peaks during the declining phase of the E. huxleyi blooms was attributed to the high bacterial activity prevailing at that time. The influence of metazooplankton grazing on DMSP and DMS production was investigated by adding moderate (24 mg dry weight m-3) and high (520 mg dry weight m-3) concentrations of Copepodite Stage V and adults of Calanus finmarchicus to two of four filtered (200 μm mesh net) enclosures during the E. huxleyi blooms. The addition of C. finmarchicus, even in high concentrations, had no apparent effect on the dynamics of E. huxleyi, suggesting that the copepods were not grazing significantly on nanophytoplankton. The addition of copepods in high concentrations favored an accumulation of chlorophyll a and particulate DMSP. These results suggest that copepods were preying on the herbivorous microzooplankton which, in turn, was controlling the biomass of nanophytoplankton. DMS production was also enhanced in the enclosure with maximum metazooplankton biomass, suggesting that the grazing of C. finmarchicus on microzooplankton containing DMSP may contribute to DMS production. These results provide strong support to the emerging idea that bacteria and metazooplankton grazing play a dominant role in determining the timing and magnitude of DMS pulses following phytoplankton blooms.
    Type of Medium: Electronic Resource
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