In:
Chinese Journal of Chemical Physics, AIP Publishing, Vol. 22, No. 1 ( 2009-02-01), p. 27-33
Abstract:
Zipf's approach in linguistics is utilized to analyze the statistical features of frequency and correlation of 16 nearest neighboring nucleotides (AA, AC, AG, , TT) in 12 human chromosomes (Y, 22, 21, 20, 19, 18, 17, 16, 15, 14, 13, and 12). It is found that these statistical features of nearest neighboring nucleotides in human genome: (i) the frequency distribution is a linear function, and (ii) the correlation distribution is an inverse function. The coefficients of the linear function and inverse function depend on the GC content. It proposes the correlation distribution of nearest neighboring nucleotides for the first time and extends the descriptor about nearest neighboring nucleotides.
Type of Medium:
Online Resource
ISSN:
1674-0068
,
2327-2244
DOI:
10.1088/1674-0068/22/01/27-33
Language:
English
Publisher:
AIP Publishing
Publication Date:
2009
detail.hit.zdb_id:
2381472-X
SSG:
6,25
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