In:
The Journal of Immunology, The American Association of Immunologists, Vol. 112, No. 4 ( 1974-04-01), p. 1383-1386
Abstract:
Neutrophils from chronic granulomatous disease (CGD) patients were compared with neutrophils from normal donors in their ability to release granular enzymes to the outside of the cell (exocytosis), when such cells are placed upon a non-phagocytizable surface coated with soluble aggregates of human γ-globulin. Based upon measurement of both granule and cytoplasmic enzymes CGD patients demonstrated no defect in exocytosis of granular enzymes when compared to normal controls. In addition these studies confirmed that an increase in hexose monophosphate shunt activity is not required for exocytosis of granule enzymes.
Type of Medium:
Online Resource
ISSN:
0022-1767
,
1550-6606
DOI:
10.4049/jimmunol.112.4.1383
Language:
English
Publisher:
The American Association of Immunologists
Publication Date:
1974
detail.hit.zdb_id:
1475085-5
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