In:
Journal of Virology, American Society for Microbiology, Vol. 8, No. 2 ( 1971-08), p. 215-224
Abstract:
Ad2 + ND 1 , a nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid virus, has been previously shown to contain a small segment of the SV40 genome covalently linked to Ad2 deoxyribonucleic acid (DNA). The SV40 portion of this hybrid virus has been characterized by relating the SV40-specific ribonucleic acid (RNA) sequences transcribed from the Ad2 + ND 1 DNA to those transcribed from the DNA of SV40 itself. RNA-DNA hybridization-competition studies indicate that the SV40 component of Ad2 + ND 1 consists of some, but not all, of that part of the SV40 genome which is transcribed early, i.e., prior to viral DNA replication, in SV40 lytic infection.
Type of Medium:
Online Resource
ISSN:
0022-538X
,
1098-5514
DOI:
10.1128/jvi.8.2.215-224.1971
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1971
detail.hit.zdb_id:
1495529-5
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