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  • 1
    Online Resource
    Online Resource
    Synthesis and Pharmacological Evaluation of New 2-aryl-3, 4-dihydro-4-oxo Quinazolin [2,3-b]-2,3-dihydro-4-phenyl [1,3,4] Thiadiazepines
    BSP Books Private Limited ; 1970
    In:  International Journal of Pharmaceutical Sciences and Nanotechnology Vol. 2, No. 4 ( 1970-01-01), p. 756-761
    Details
    In: International Journal of Pharmaceutical Sciences and Nanotechnology, BSP Books Private Limited, Vol. 2, No. 4 ( 1970-01-01), p. 756-761
    Abstract: Three different 3-amino-2-mercaptoquinazolin-4(3H)-ones were prepared from the substituted anthranilic acids. Likewise four different chalcones were also prepared by mixed aldol condensation of four aromatic aldehydes with acetophenone. Each of the 3-amino, 2-mercapto quinazolinones was subjected to a cycloaddition reaction with chalcones, separately by heating under reflux in acetic anhydride. The product obtained in each case has been purified and characterized as the respective 2-aryl-3,4-dihydro-4-oxoquinazolin-[2,3-b]-2,3-dihydro-4-phenyl –1,3,4-thiadiazepine on the basis of  their analytical and spectral data.             These new fused thiadiazepines were evaluated for their locomotor, anti psychotic and muscle relaxant activities by standard methods using animal models and compared with that of standard employed
    Type of Medium: Online Resource
    ISSN: 0974-3278
    URL: Article
    DOI: 10.37285/ijpsn.2009.2.4.10
    Language: Unknown
    Publisher: BSP Books Private Limited
    Publication Date: 1970
    Location Call Number Limitation Availability
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  • 2
    Online Resource
    Online Resource
    Aerosol Number Size Distribution Measurements at Hanle, a Free Tropospheric High-Altitude Site in Western Himalayas
    Nepal Journals Online (JOL) ; 1970
    In:  Journal of the Institute of Engineering Vol. 8, No. 3 ( 1970-01-01), p. 140-146
    Details
    In: Journal of the Institute of Engineering, Nepal Journals Online (JOL), Vol. 8, No. 3 ( 1970-01-01), p. 140-146
    Abstract: Aerosol characteristics over the high altitude stations, akin to pristine and free conditions are important to understand the background aerosol features against which polluted and urban environments could be compared. In addition it is also important to monitor the changes brought about by the large-scale processes, which result in lofting and transporting of aerosols from different source regions to higher altitude levels. Moreover, these aerosols have a significant role in modifying clouds especially cold clouds. The availability of significant amount of solar UV radiation at these altitudes, along with water vapour and OH, if present, makes these regions conducive for formation of new particles from gas phase reaction products involving precursors of natural or anthropogenic origin. Such processes play a significant role in modulating the size distribution of free tropospheric aerosols and hence their radiative impacts. In this work, aerosol number size distribution measurements carried out from a high altitude free tropospheric Himalayan location, Hanle (32.78°N, 78.96°E, 4530 m amsl) during the period from May through December 2010 are examined. The monthly mean total number concentration (Nt) increased from May (614 ± 188 cm-3) to October (1498 ± 792 cm-3) and decreased slightly through December (1158 ± 470 cm-3). Fine mode aerosols (size 〈 100nm) contributed mostly to the total number concentration. The fractional contribution of the fine mode aerosols to the total number concentration, showed a clear increasing trend from May (~ 0.57) to December (~ 0.81). The number size distribution, which remained unimodal in May, June months with a mode in accumulation size range (around 100nm), changed to a bimodal distribution subsequently with a mode in the nucleation size range ( 〈 25nm), indicating the possibility of new particle formation. The results are discussed in light of the possible association between the variation of the aerosol number concentration to long-range transport and thermally driven mesoscale processes such as mountain/valley winds. DOI: http://dx.doi.org/10.3126/jie.v8i3.5940 JIE 2011; 8(3): 140-146
    Type of Medium: Online Resource
    ISSN: 1810-3383
    URL: Article
    DOI: 10.3126/jie.v8i3.5940
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 1970
    detail.hit.zdb_id: 2677761-7
    Location Call Number Limitation Availability
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Columnar Aerosol Extinction Characteristics: Measurements from a Free-Tropospheric Observatory in Western-Himalayas
    Nepal Journals Online (JOL) ; 1970
    In:  Journal of the Institute of Engineering Vol. 8, No. 3 ( 1970-01-01), p. 52-57
    Details
    In: Journal of the Institute of Engineering, Nepal Journals Online (JOL), Vol. 8, No. 3 ( 1970-01-01), p. 52-57
    Abstract: Continuous measurements of spectral aerosol optical depths (AOD) were made over a very high altitude aerosol observatory at Hanle (32.76°N, 78.95°E, 4520 m amsl), during the summer and autumn of 2009 and 2010, by using a 10-channel multi-wavelength radiometer (MWR). The results depicted very low values of AOD (with a mean for the measurement period as ~ 0.071 ± 0.003 at 500 nm), but with a spectral dependence that changed with the months from ~ 0.8 to 1.3, with a mean value of ~ 1.01 ± 0.06. The AODs though were in general comparable to those seen over pristine Antarctic environments, are quite significant when we consider the altitude of the station. The details are presented. DOI: http://dx.doi.org/10.3126/jie.v8i3.5931 JIE 2011; 8(3): 52-57
    Type of Medium: Online Resource
    ISSN: 1810-3383
    URL: Article
    DOI: 10.3126/jie.v8i3.5931
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 1970
    detail.hit.zdb_id: 2677761-7
    Location Call Number Limitation Availability
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    Online Resource
  • 4
    Online Resource
    Online Resource
    Black Carbon Aerosol over a High Altitude (~ 4.52 km) Station in Western Indian Himalayas
    Nepal Journals Online (JOL) ; 1970
    In:  Journal of the Institute of Engineering Vol. 8, No. 3 ( 1970-01-01), p. 42-51
    Details
    In: Journal of the Institute of Engineering, Nepal Journals Online (JOL), Vol. 8, No. 3 ( 1970-01-01), p. 42-51
    Abstract: Continuous measurements of mass concentration of Black Carbon (BC) aerosols, measured from a high altitude (~ 4.5 km above msl) location, Hanle (32.78°N, 78.95°E) in the western Himalayas, during August 2009 to July 2010 have been examined. The day-to-day variations in BC mass concentration (MB) were rather subdued in winter months while quite conspicuous during the spring months. It showed a well defined annual cycle with a maximum (109 ± 78 ng m-3) during spring and minimum during the winter (66 ± 62 ng m-3) season with an annual average MB of 78 ± 64 ng m-3. Examining the frequency distribution, it was found that 64 % of the values were below annual mean MB showing a rather pristine nature for this near free tropospheric region. Trajectory clustering and concentration weighted trajectory (CWT) analysis indicated that, most of the year, the site is influenced from the advection from west and south west Asian locations and only for a small period from the Indo-Gangetic Plains (IGP). The observations are compared with other high altitude measurements, over the globe in general and around the Himalayan region. DOI: http://dx.doi.org/10.3126/jie.v8i3.5930 JIE 2011; 8(3): 42-51
    Type of Medium: Online Resource
    ISSN: 1810-3383
    URL: Article
    DOI: 10.3126/jie.v8i3.5930
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 1970
    detail.hit.zdb_id: 2677761-7
    Location Call Number Limitation Availability
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    Online Resource
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