ISSN:
1435-232X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The distribution of Gc subtypes in a sample from 310 unrelated healthy Japanese living in Tokyo was examined by a slab polyacrylamide gel isoelectrofocusing followed by immunofixation. At least 9 phenotypes were distinguished which can be ascribed to four alleles:Gc 1F,Gc 1S,Gc 2 andGc J. The allele frequencies were 0.4656, 0.2590, 0.2574 and 0.0180, respectively. It was confirmed thatGc J has a polymorphic frequency in Japanese. Furthermore, two unusual phenotypes were encountered, one with a variant Gc 1 and the other with a variant Gc 2 protein, indicating the occurrence in Japanese of two further Gc alleles.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02001792
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