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  • 1975-1979  (3)
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  • 1
    Electronic Resource
    Electronic Resource
    Experimental transmission of Leishmania chagasi , causative agent of neotropical visceral leishmaniasis, by the sandfly Lutzomyia longipalpis (1977)
    [s.l.] : Nature Publishing Group
    Nature 266 (1977), S. 628-630 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In transmission experiments we used an isolate (L.d./PP-75) of L. chagasi obtained from a child from Ituau, Bahia State, Brazil. The parasite was passed from the original culture medium in which it was isolated, directly into hamsters: it had been passaged in these animals on only three occasions ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/266628a0
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Epidemiology and ecology of leishmaniasis in Latin-America (1978)
    [s.l.] : Nature Publishing Group
    Nature 273 (1978), S. 595-600 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Of the diseases caused by protozoal parasites, leishmaniasis is probably second in importance only to malaria. Chemotherapeutic drugs are toxic, expensive and not 100% effective. This, and the absence of any non-living vaccine against the disease, means that control depends on eliminating either ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/273595a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Electrical properties ofValonia ventricosa (1976)
    Springer
    The journal of membrane biology 29 (1976), S. 81-94 
    Details
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The cytoplasmic electrical potential and membrane resistance of mature cells ofValonia ventricosa have been measured by inserting a microelectrode concentric with another electrode into the vacuole of the cell. The cytoplasmic region was investigated by advancing the microelectrode into the cell wall from the vacuolar side. The results revealed a unique region where the vacuolar electric potential and membrane resistance changed in a simultaneous single step to values close to zero. The measured potential always remained positive immediately after the step. At no time was a highly negative potential region encountered. Further penetration of the microelectrode revealed a low resistance negative potential region of −12.6±1.1 mV associated with the cell wall. Experiments were also carried out on aplanospores ofV. ventricosa to compare mature and immature cells. The chemical composition of the vacuolar and protoplasmic phases of mature cells was determined. The results agreed with previous results except that the Cl− ion content of the protoplasm was significantly higher at 381±20 mmoles/liter (H2O). It was concluded that mature cells ofValonia are significantly different from immature cells in that no highly negative potential cytoplasmic region was found in mature cells. It was considered that the measured step change in electric potential and membrane resistance occurred at the plasmalemma and that the tonoplast was a region of very low resistance. The implications of these findings in terms of models of ion transport intoValonia are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01868953
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    Paper (German National Licenses)
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