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  • 1
    Electronic Resource
    Electronic Resource
    Cell-surface antigens induced by RNA tumour viruses (1979)
    [s.l.] : Nature Publishing Group
    Nature 279 (1979), S. 197-201 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Host animals show an immune response to the surface of cells infected with RNA tumour viruses. An element of this response is due to expression of viral structural antigens, but the major part is due to virus-induced cell-surface antigens (CSAs). This article compares the properties of CSAs of the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/279197a0
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  • 2
    Electronic Resource
    Electronic Resource
    Surface Markers on Human B and T Lymphocytes (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 4 (1975), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Almost 100% of peripheral T lymphocytes are shown to have the capacity to form rosettes with human lymphoblastoid B-cell lines, predominantly at 4°C and with lines having surface-bound IgG. Blast-transformed T cells retained this capacity and formed rosettes even at 37°C Unstimulated T cells bound less readily to B-cell blasts, stimulated by pokeweed mitogen for 72 hr. Even though rosettes, formed at 4°C, were stable for several hours at 72°C, no T-cell-mediated cytotoxicity could be detected during overnight incubation. Extreme pH values and trypsinization decreased rosette formation, whereas neuraminidase treatment enhanced the reaction. Rosette formation was independent of bivalent cations and unimpaired in the presence of inhibitors (NaF. NaN3), undiluted human or fetal call sera, protein A, sonicated sheep erythrocyte membranes, and normal or heat-aggregated human IgG. Anti-Ig, anti β2-microglobulin, or anti-T cell sera did not influence rosette formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-3083.1975.tb02625.x
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  • 3
    Electronic Resource
    Electronic Resource
    DISCUSSION PAPER: EFFECT OF SUPERNATANTS FROM LONG-TERM LYMPHOID CELL LINES ON METASTATIC CUTANEOUS TUMORS FOLLOWING LOCAL INJECTION (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 276 (1976), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1976.tb41685.x
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  • 4
    Electronic Resource
    Electronic Resource
    17. Konservative therapie der hyperthyreose vom Typ M. Basedow (indikation und taktik) (1978)
    Springer
    Langenbeck's archives of surgery 347 (1978), S. 131-136 
    Details
    ISSN: 1435-2451
    Keywords: Autoimmunology ; Antithyroid substances ; Steroid hormones ; Radioactive iodine ; Immunpathogenese ; Steroidbehandlung ; Antithyreoidale Substanzen ; Radiojodtherapie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Spezielle Behandlungsmaßnahmen sind 1. Stoßartig Steroidhormone, 2. Antithyreoidale Substanzen, 3. Radiojod, 4. Strumaresektion. Die ersten beiden sind passagere Verfahren und ergänzen die definitiven nuklearmedizinischen und operativen Behandlungsmaßnahmen. Differentialtherapeutische Erwägungen knüpfen sich an Lebensalter und Kropfgröße. Für ca. 60 % aller Fälle ist die Radiojodtherapie optimal, je größer eine hyperthyreotische Struma, desto eher ist die Operation indiziert. Detaillierte Gesichtspunkte werden anhand von 3580 eigenen Fällen von Hyperthyreose erörtert.
    Notes: Summary Special procedures are: (1) Short-term treatment with steroid hormones; (2) antithyroid substances; (3) radioactive iodine; (4) operation. The first two methods are complementary to the definitive procedures of isotope and surgical therapy. The indications conform to the age of the patient and the size of the goiter. The treatment of choice in 60 % of all cases is radioactive iodine; 20–25 % are treated with antithyroid substances only for several years. The remaining cases, complicated by goiters of size II and more, should be handled surgically. Discussion based on personal experience with 3580 cases over 20 years).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01579318
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  • 5
    Electronic Resource
    Electronic Resource
    γ-Detected NMR of103 mRhFe (1977)
    Springer
    The European physical journal 281 (1977), S. 341-346 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Using the method ofγ-detection, the NMR in the metastable 40 keV-state of103Rh in Fe (thin foils with diffused103Pd activity) was measured in external fields of 0.5 to 14 kG. We find a zero-field resonance frequency ofv 0=(550.3±0.5) MHz and a slope ofdv/dH= −(0.933 ±0.017) MHz/kG, yielding g=1.22 ± 0.02. The resulting value for the hyperfine field, Hhf=(590±10) kG, is inconsistent with that of an NMR measurement in the ground state of103Rh. Possible reasons for this discrepancy are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01408181
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  • 6
    Electronic Resource
    Electronic Resource
    Neuroendocrine function in long-term pinealectomized male rats, following visual and audiogenic stress (1979)
    Springer
    Journal of neural transmission 46 (1979), S. 113-122 
    Details
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intact, sham-pinealectomized and pinealectomized adult male rats were maintained for 10 weeks on a light∶dark (L∶D) cycle of 12∶12, with lights on at 6 a.m. Subsequently they were acutely exposed to (1) visual or (2) audiogenic stress for periods of 2 or 30 min, immediately following which they were decapitated and serum ACTH, corticosterone, FSH, LH, PRL and TSH concentrations were determined. Serum ACTH and corticosterone levels were similar in control and operated groups following both types of stresses. Serum FSH and LH concentrations were elevated in pinealectomized animals as compared to controls, following 30 min of exposure to visual stimulation; no difference in these parameters was observed between the groups following audiogenic stress. Serum PRL levels tended to be lower in pinealectomized animals following both stresses. Serum TSH concentrations following visual stimulation were similar in all groups, but audiogenic stimulation resulted in elevated TSH levels as compared to controls. These data demonstrate that the pineal gland plays an integral role in the responses of the parvicellular neuroendocrine axes to acute neurogenic stress. Possible molecular bases for this involvement are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01250333
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  • 7
    Electronic Resource
    Electronic Resource
    Adjuvant immunotherapy in acute nonlymphocytic leukemia (1978)
    Springer
    Cancer immunology immunotherapy 4 (1978), S. 179-183 
    Details
    ISSN: 1432-0851
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Of 112 patients (maximum age 70 years) with acute nonlymphocytic leukemia, 62 (55%) went into remission on an induction therapy of cytosine arabinoside and daunorubicin. 20 patients were randomized for maintenance treatment consisting of chemotherapy only and 22 patients for combined chemo-immunotherapy. The chemotherapy consisted in 5-day courses of daunorubicin and cytosine arabinoside and of thioguanine and cytosine arabinoside, alternating every month. The chemo-immunotherapy group also received weekly intracutaneous injections of 109 allogeneic nonirradiated leukemic myeloblasts and 106 BCG organisms (Glaxo) by Heaf gun. The median duration of the first remission was 164 days for the chemotherapy group and 464 days for the chemo-immunotherapy group. The corresponding median times of survival were 344 days for the first group and 734 days for the second group. The difference concerning median duration of survival is statistically significant. Thus immunotherapy seems to prolong survival.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00204737
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  • 8
    Electronic Resource
    Electronic Resource
    Mental health students' reactions to a group training conference: Understanding from a systems perspective (1975)
    Springer
    Social psychiatry and psychiatric epidemiology 10 (1975), S. 79-85 
    Details
    ISSN: 1433-9285
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This is an investigation of the experience of a group of mental health students who, as part of their training, participated in a four day non-residential Group Relations Conference composed of analytically oriented (Tavistock) and social psychologically oriented (NTL) groups. The investigation focuses on who subsequently joins groups, what is learned in Tavistock and NTL groups, and the relationship between the Training Conference and the progress or initiation of psychotherapy. Striking similarity is found among those who join and those who do not join groups following the conference. Learning in the conference centers on issues of power and authority and less on more personal, individual concerns. The absence of “group casualties” is noted. In order to place the results in a broader framework the findings are evaluated from a systems perspective.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00577996
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  • 9
    Electronic Resource
    Electronic Resource
    Human tumor — Lymphocyte interaction in vitro (1978)
    Springer
    Cancer immunology immunotherapy 5 (1978), S. 63-69 
    Details
    ISSN: 1432-0851
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Biopsy derived tumor cells have been tested for capacity to induce DNA synthesis in autologous blood lymphocytes in vitro (ATS test). In the present series 5/20 biopsies were ATS positive when mechanically separated cells were used. Preincubation of the tumor cells at 37° C, but not at 0° C, markedly increased the stimulating capacity. Parallel experiments gave 7/9 positive tests with preincubated and 3/9 positive tests with cells used directly. When the biopsy cells were brought into suspension by enzyme treatment they did not stimulate unless incubated at 37° C before confronting the lymphocytes. In accordance with previous results, the presence of autologous serum during ATS inhibited the reaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00199978
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  • 10
    Electronic Resource
    Electronic Resource
    Dynamic measurement of the Kapitza resistance (1978)
    Springer
    Journal of low temperature physics 33 (1978), S. 403-412 
    Details
    ISSN: 1573-7357
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: To measure the Kapitza resistance between a solid and liquid helium, a thin sample is immersed in the liquid and subjected to pulsed heating. The Kapitza resistance is determined from the time variation of the sample temperature, measured by a built-in nuclear orientation thermometer. The system Au/dilute 3He-4He is used as an example. Potentials and limitations of the method are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00115565
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