In:
Canadian Journal of Chemistry, Canadian Science Publishing, Vol. 56, No. 1 ( 1978-01-01), p. 62-70
Abstract:
Studies involving selective functionalization of the indole unit in a number of bisindole alkaloids and related synthetic derivatives are described. These investigations include such reagents as tert-butyl hydroperoxide, which provides an efficient procedure for epoxidation of olefinic linkages, mercuric acetate, osmium tetroxide, and iodine under basic conditions and oxygenation under acidic conditions. Efficient syntheses of leurosine (8) and various novel vinblastine derivatives are developed.
Type of Medium:
Online Resource
ISSN:
0008-4042
,
1480-3291
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
1978
detail.hit.zdb_id:
1482256-8
Permalink