In:
The Journal of Immunology, The American Association of Immunologists, Vol. 119, No. 3 ( 1977-09-01), p. 1138-1144
Abstract:
The proliferative response induced by the B cell activating ligand dextran-sulfate (D×S) requires the presence of macrophage-produced factors or the macrophage-substituting compound 2-mercaptoethanol. Thus, the mechanism for activation of mouse B splenic lymphocytes is different for D×S than for other polyclonal B cell activators such as lipopolysaccharides, which can trigger B cells directly in the absence of helper factors. It is suggested that the disappearance of the D×S-induced response could be studied in a simple functional test for the efficiency of macrophage depletion obtained by different techniques.
Type of Medium:
Online Resource
ISSN:
0022-1767
,
1550-6606
DOI:
10.4049/jimmunol.119.3.1138
Language:
English
Publisher:
The American Association of Immunologists
Publication Date:
1977
detail.hit.zdb_id:
1475085-5
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