GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Na+ transport by rabbit urinary bladder, a tight epithelium (1976)
    Springer
    The journal of membrane biology 28 (1976), S. 1-40 
    Details
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary By in vitro experiments on rabbit bladder, we reassessed the traditional view that mammalian urinary bladder lacks ion transport mechanisms. Since the ratio of actual-to-nominal membrane area in folded epithelia is variable and hard to estimate, we normalized membrane properties to apical membrane capacitance rather than to nominal area (probably 1 μF ∼ 1 cm2 actual area). A new mounting technique that virtually eliminates edge damage yielded resistances up to 78,000 ΩμF for rabbit bladder, and resistances for amphibian skin and bladder much higher than those usually reported. This technique made it possible to observe a transport-related conductance pathway, and a close correlation between transepithelial conductance (G) and short-circuit current (I sc) in these tight epithelia.G andI sc were increased by mucosal (Na+) [I sc∼0 when (Na+)∼0], aldosterone, serosal (HCO 3 − ) and high mucosal (H+); were decreased by amiloride, mucosal (Ca++), ouabain, metabolic inhibitors and serosal (H+); and were unaffected by (Cl−) and little affected by antidiuretic hormone (ADH). Physiological variation in the rabbits' dietary Na+ intake caused variations in bladderG andI sc similar to those caused by the expectedin vivo changes in aldosterone levels. The relation betweenG andI sc was the same whether defined by diet changes, natural variation among individual rabbits, or most of the above agents. A method was developed for separately resolving conductances of junctions, basolateral cell membrane, and apical cell membrane from thisG−I sc relation. Net Na+ flux equalledI sc. Net Cl− flux was zero on short circuit and equalled only 25% of net Na+ flux in open circuit. Bladder membrane fragments contained a Na+−K+-activated, ouabain-inhibited ATPase. The physiological significance of Na+ absorption against steep gradients in rabbit bladder may be to maintain kidney-generated ion gradients during bladder storage of urine, especially when the animal is Na+-depleted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01869689
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The mechanism of Na+ transport by rabbit urinary bladder (1976)
    Springer
    The journal of membrane biology 28 (1976), S. 41-70 
    Details
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The mechanism of Na+ transport in rabbit urinary bladder has been studied by microelectrode techniques. Of the three layers of epithelium, the apical layer contains virtually all the transepithelial resistance. There is radial cell-to-cell coupling within this layer, but there is no detectable transverse coupling between layers. Cell coupling is apparently interrupted by intracellular injection of depolarizing current. The cell interiors are electrically negative to the bathing solutions, but the apical membrane of the apical layer depolarizes with increasingI sc. Voltage scanning detects no current sinks at the cell junctions or elsewhere. The voltage-divider ratio, α, (ratio of resistance of apical cell membrane,R a, to basolateral cell membrane,R b) decreases from 30 to 0.5 with increasingI sc, because of the transportrelated conductance pathway in the apical membrane. Changes in effective transepithelial capacitance withI sc are predicted and possibly observed. The transepithelial resistance,R t, has been resolved intoR a, Rb, and the junctional resistance,R j, by four different methods: cable analysis, resistance of uncoupled cells, measurements of pairs of (R t, α) values in the same bladder at different transport rates, and the relation betweenR t andI sc and between α andI sc.R j proves to be effectively infinite (nominally 300 kΩ μF) and independent ofI sc, andR a decreases from 154 to 4 kΩ μF with increasingI sc. In the resulting model of Na+ transport in “tight” epithelia, the apical membrane contains an amiloride-inhibited and Ca++-inhibited conductance pathway for Na+ entry; the basolateral membrane contains a Na+−K+-activated ATPase that extrudes Na+; intracellular (Na+) may exert negative feedback on apical membrane conductance; and aldosterone acts to stimulate Na+ entry at the apical membrane via the amiloride-sensitive pathway.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01869690
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Comparison of the pharmacokinetics of intravenous dl-propranolol in borderline and permanent hypertension (1976)
    Springer
    European journal of clinical pharmacology 10 (1976), S. 387-393 
    Details
    ISSN: 1432-1041
    Keywords: Pharmacokinetics ; dl-propranolol ; borderline hypertensives ; permanent hypertensives ; cardiac output
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In borderline and permanent hypertensives after rapid i.v. injection of dl-propranolol 0.2 mg/kg plasma levels were measured and were fitted to a two-compartment open-model. In borderline patients, characterized by a high basal cardiac output (CO), plasma levels were always lower than in permanent hypertensives. The biological half-life was reduced and the central volume of distribution, volume of distribution at pseudo-equilibrium and total clearance (TC) were markedly increased. In the overall population, there was a significant positive correlation between CO and TC. Rapid achievement of a predetermined plateau in each group constituted experimental proof of the validity of the two-compartment open-model for kinetic analysis of propranolol i.v. If kinetic parameters from permanent hypertensives were applied to borderline hypertensives a lower plateau was obtained. Thus, in so far as β-blockade is related to plasma level of propranolol, an increased intravenous dose may be required in patients with high CO.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00563074
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    THERMOSTABLE POLYGALACTURONASE SECRETED BY Sclerotinia fructigena (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 40 (1975), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1975.tb02220.x
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Formation of Mn4+ centers in MgO powder due to nitrobenzene treatment in liquid phase (1979)
    Springer
    Reaction kinetics and catalysis letters 10 (1979), S. 347-351 
    Details
    ISSN: 1588-2837
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Abstract Методом ЭПР спектроскопии исследован порошок MgO, активированный в вакууме при 400°C, и пропитанныи нитробензолом. Было установлено, что образование центров mn4+ является результатом перехода электронов между нитробензолом и центрами примеси. По сравнению с методом парофазного контакта катализатора с нитробензолом, жидкофазное пропитывание дает гораздо меньшую концентрацию радикала-аниона нитробензола.
    Notes: Abstract MgO powders activated in vacuo at 400°C and impregnated with nitrobenzene were investigated by ESR spectroscopy. The formation of Mn4+ centers due to electron transfer between nitrobenzene and impurity centers was established. Liquid impregnation yields substantially fewer nitrobenzene anion radicals than vapor-contact between the catalyst and nitrobenzene.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02075322
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Hypothesis for origin of planktonic patchiness (1976)
    [s.l.] : Nature Publishing Group
    Nature 259 (1976), S. 659-659 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The results that we describe depend on two hypothesised properties of the full equations: an autocatalytic effect in phytoplankton density which is attributed to a reduced efficiency of herbivory as phytoplankton density increases (a Moiling8 Type 2 functional response), and differential dispersal ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/259659a0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Active sodium transport by mammalian urinary bladder (1975)
    [s.l.] : Nature Publishing Group
    Nature 253 (1975), S. 747-748 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sheets of rabbit urinary bladder were mounted in vitro between temperature-controlled (37 C) Plexiglass chambers with 2 cm2 exposed. The bathing solution was 110 mM NaCl, 7 mM KC1, 25 mM NaHCO3, 2 mM CaCl2, 2 mM MgSO4, 1.2 mM NaH2PO4, and 10 mM glucose, gassed with 5% CO2-95% O2 OH 7.4). Three ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/253747a0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Über einen Fall von akuter Formaldehydvergittung mit nachfolgender tödlicher Milchaspiration (1966)
    Springer
    Archives of toxicology 21 (1966), S. 279-283 
    Details
    ISSN: 1432-0738
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Eine 41 Jahre alte Frau trank ca. 200 cm3 einer 35% igen Formaldehydlösung. Infolge Einflößung von kondensierter Milch seitens des Ehemannes verstarb sie durch Ersticken. Möglichkeiten der Abgrenzung eines Erstickungstodes bei gleichzeitig vorliegender Formaldehydvergiftung werden aufgezeigt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00583842
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    The influence of human activities on breeding and spawning of littoral marine bottom invertebrates (1968)
    Springer
    Helgoland marine research 17 (1968), S. 200-208 
    Details
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Summary 1. The influences of human activities on the breeding and spawning of marine littoral bottom invertebrates are discussed on the basis of information from literature and own results. 2. Human activities (e. g. heated effluents, chemical water pollution, ship activities, pollution of big rivers) modify living conditions and biological activities of bottom invertebrates in various ways; the major biological consequences are listed below under points 3 to 6. 3. Human activities, especially local heating, may change time and seasonal pattern of spawning in local populations; in extreme cases spawning may be completely inhibited. 4. Heated effluents may provide suitable living conditions for tropical or subtropical species originally foreign to the area and thus change the species composition of the local ecosystem. 5. Human activities may stimulate gamete shedding outside the normal season. 6. Human activities may change the normal succession of local mero-plankton forms and thus alter quantitative and qualitative interrelations between different components of the biocoenosis. 7. The detrimental effects of human activities tend to be most severe in shallow, semi-enclosed areas. Consequently, the southern North Sea represents an area which deserves particular attention.
    Notes: Kurzfassung Die Einflüsse menschlichen Wirkens auf die Laich- und Fortpflanzungstätigkeit mariner, litorallebender Bodenevertebraten werden an Hand von Literaturbearbeitungen und eigener Forschungsergebnisse erörtert. Besondere Berücksichtigung erfahren dabei die Erwärmung lokaler Bereiche durch das Kühlwasser von Kraftwerken, chemische Wasserverunreinigung, Schiffsverkehr und größere Flüsse. Als biologische Konsequenzen, die insbesondere in flachen, teilweise eingeschlossenen Meeresgebieten ein starkes Ausmaß erreichen können, werden angeführt: (1) Veränderungen hinsichtlich des Zeitpunkts und jahreszeitlichen Ablaufs des Laichgeschäfts einheimischer Populationen; (2) Einwanderung tropischer und subtropischer Arten in lokal erwärmte Gebiete; (3) Stimulation der Gametenausschüttung außerhalb der normalen Laichzeiten; (4) Veränderungen in der normalen Sukzessionsfolge lokaler Planktonpopulationen; (5) Quantitative und qualitative Verschiebungen im planktonischen Ökosystem.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01611223
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Polymerization of liquid propylene on amine-modified Ziegler-Natta catalysts (1979)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 17 (1979), S. 1871-1875 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1979.170170634
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...