In:
Liebigs Annalen der Chemie, Wiley, Vol. 1983, No. 2 ( 1983-02-15), p. 220-225
Abstract:
Synthesis of the Lycopodium ‐Alkaloids rac‐α‐Obscurin through 1,3‐Anullation of an Enimine Acid catalysed 1,3‐annulation of 1,2,3,4‐tetrahydro‐6‐methyl‐2‐oxopyridine ( 1 ) to the enimine 3 , followed by methylation, provides a new regio and stereoselective route to rac ‐α‐obscurine ( 5 ). Reduction of rac‐N ‐demethyl‐α‐obscurine with LiAlH 4 yields rac ‐lycodine ( 11 ) and rac ‐deacetyl‐flabellidine ( 9 ). A new pathway for the biogenesis of the β‐amino‐imine 9 is suggested.
Type of Medium:
Online Resource
ISSN:
0170-2041
DOI:
10.1002/jlac.v1983:2
DOI:
10.1002/jlac.198319830206
Language:
English
Publisher:
Wiley
Publication Date:
1983
detail.hit.zdb_id:
1475010-7
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