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  • Wiley-Blackwell  (33)
  • Nature Publishing Group  (1)
  • 1980-1984  (11)
  • 1965-1969  (17)
  • 1935-1939  (6)
  • 1
    Electronic Resource
    Electronic Resource
    Evidence for a role of plasma kallikrein in the activation of prorenin (1980)
    [s.l.] : Nature Publishing Group
    Nature 283 (1980), S. 482-483 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] If kallikrein is the in vivo activator of prorenin, a negative correlation between kallikrein (urinary or plasma) and the proportion of prorenin (prorenin/total renin) may be expected. In 13 normal human volunteers, urinary kallikrein excretion and plasma prekallikrein concentration were correlated ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/283482a0
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  • 2
    Electronic Resource
    Electronic Resource
    Statistische Synthesen von Rotaxanen (1980)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 113 (1980), S. 941-954 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Statistical Syntheses of RotaxanesThe acetalisation of the 28-membered cyclic diols 11a, b with the long-chain dibromo ketone 12 gives acetals 13a, b. These compounds react with triphenylmethyllithium to give 17a, b and 18a, b from which the rotaxanes 20a, b are obtained in 0.066 or 0.18 and 0.12% yield, respectively, after hydrolysis of the acetal bonds. The reacetalisation of rotaxane 20b affords, by an intraannular reaction, the prerotaxane 18b in pure form.
    Notes: Die Acetalisierung der 28-gliedrigen cyclischen Diole 11a, b mit dem langkettigen Dibromketon 12 ergibt die Acetale 13a, b. Nach Umsetzung mit Triphenylmethyllithium zu 17a, b und 18a, b werden nach Hydrolyse der Acetalbindungen die Rotaxane 20a, b in Ausbeuten von 0.066 und 0.18 bzw. 0.12% als farblose Öle isoliert. Durch Reacetalisierung von 20b wird in einer intraannularen Reaktion das Prärotaxan 18b in reiner Form erhalten.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19801130314
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  • 3
    Electronic Resource
    Electronic Resource
    Reduktive Spaltung von 2,2-Dialkyl-1,3-benzodioxol-Derivaten mit Diisobutylaluminiumhydrid. Synthese eines [2]-Catenans mit einem 22-gliedrigen Makroheterocyclus (1980)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 113 (1980), S. 3697-3705 
    Details
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Reductive Cleavage of 2,2-Dialkyl-1,3-benzodioxole Derivatives with Diisobutylaluminium Hydride. Synthesis of a [2]-Catenane having a 22-Membered MacroheterocycleThe reductive cleavage of the title compounds 1 with diisobutylaluminium hydride in refluxing benzene or toluene affords, after hydrolysis, pyrocatechol derivatives 8 and a mixture of alkenes 6 and alkanes 7. When the reaction is performed at room temperature, the pyrocatechol monoalkyl ethers 4 are obtained after hydrolysis. Starting from the precatenane 9, the catenane 12 having a 22-membered macroheterocycle is synthesised in a reaction sequence of several steps.
    Notes: Die reduktive Spaltung der Titelverbindungen 1 mit DIBAH in siedendem Benzol oder Toluol ergibt nach Hydrolyse Brenzcatechin-Derivate 8 und ein Gemisch von Alkenen 6 und Alkanen 7. Die Reaktionsführung bei Raumtemperatur ergibt Brenzcatechin-monoalkylether 4. Ausgehend von dem Praecatenan 9 wird in einer mehrstufigen Reaktionsfolge das Catenan 12 mit einem 22-gliedrigen Makroheterocyclus synthetisiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19801131203
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  • 4
    Electronic Resource
    Electronic Resource
    Untersuchungen zur Kavitation bei oszillierenden VerdrängerpumpenVorgetragen vom erstgenannten Autor auf dem Jahrestreffen der Verfahrens-Ingenieure, 1. bis 3. Oktober 1968 in Stuttgart. (1969)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 41 (1969), S. 271-278 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An einer Kolbenpumpe mit Acrylglas-Zylinder wird das Verhalten der Ventile ohne Kavitation und bei verschiedener Stärke der Dampfblasenbildung beobachtet und anhand von Ventilhub- und Druckabfallkurven diskutiert. Die Ergebnisse werden mit stationären Messungen verglichen. Es zeigt sich, daß bei nichtkavitierendem Pumpenbetrieb der Druckabfall im Saugventil aus den bei stationärer Strömung gemessenen Verlustbeiwerten ζv = f (Re) berechnet werden kann. Abschließend werden die Auswirkungen verschiedener Kavitationszustände auf das Betriebsverhalten der Pumpe beschrieben und Maßnahmen zur Vermeidung schädlicher Kavitation genannt.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330410510
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  • 5
    Electronic Resource
    Electronic Resource
    Ausführung, Eigenschaften und Anwendung stopfbuchsloser Dosierpumpen (1967)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 39 (1967), S. 449-457 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Zur Dosierung gefährlicher, aggressiver und verschleißend wirkender Medien werden immer häufiger stopfbuchslose Dosierpumpen in Faltenbalg- und Membranausführung angewendet. Hierbei haben die Pumpen mit mechanischem Verdrängerantrieb den Vorzug einfacher Bedienung und Wartung, jedoch sind Förderströme, Förderdrücke und Temperaturen begrenzt. Die komplizierteren und teureren Ausführungen mit hydraulischem Verdrängerantrieb gestatten auch höhere Drücke; der Verdränger wird günstiger beansprucht, und das Hubvolumen ist stets genau definiert. Auf Grund von Untersuchungsergebnissen, Auslegungs- und Anwendungserfahrungen werden Anwendungsbereich, Saugvermögen, Strahlenresistenz, Förderverhalten, Dosiergenauigkeit, Lebensdauer und Dichtheit der stopfbuchslosen Dosierpumpen erörtert. Für die Planung dient ein Überblick zur Anwendung stopfbuchsloser Dosierpumpen.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330390802
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  • 6
    Electronic Resource
    Electronic Resource
    Evidence for aryl participation in mass spectrometric fragmentation processes (1969)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 2 (1969), S. 781-790 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: While heterolysis of oxonium ions generated upon electron-impact in the mass spectrometer is a well documented phenomenon in the fragmentation of aliphatic ethers, little analogy exists for structurally comparable immonium ions. Exceptions are ions of the latter class in which dissociation is facilitated by the presence of proper substituents in position allowing satabilization of daughter ions. Two main types of subtitution were explored providing(1) resonance stabilization of the product ions by aryl substituents in benzylic,heterolysis,and (2) aryl neighboring group participation in homobenzylic heterolysis, possibly yielding phenonium ions (or isometric ions via further rearrangement) as stable products in the gas phase. In the discussion emphasis will be placed on Case 2.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210020803
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  • 7
    Electronic Resource
    Electronic Resource
    Nicotinates as derivatives for the mass spectrometric investigation of long chain alcohols (1981)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 16 (1981), S. 118-122 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The mass spectra of the nicotinates of two methyl branched and one unsaturated long chain alcohol were compared with the mass spectra of the underivatized alcohols and of their trimethylsilyl ethers. It is shown that the structure of the chain is much more clearly shown by the spectra of the nicotinates than in the other spectra.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210160304
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  • 8
    Electronic Resource
    Electronic Resource
    Morphogenesis and histochemistry of the developing mouse kidneyThis investigation was supported in part by a research grant from the Southeastern Pennsylvania Heart Association.Preliminary reports of this research were presented at the summer meeting of the American Society of Zoologists, University of Illinois, Urbana, August 16-20, 1965. Abstracts appeared in the American Zoologist 5(2): 249-250. (1966)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 120 (1966), S. 135-155 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A morphological and histochemical investigation was conducted on the pronephros and mesonephros of the mouse embryo from 8.5 through 16.5 days. The pronephros appeared between days 8.5 and 9.5 as a thickening of the somatic layer of the intermediate cell mass. It consisted of three small clusters of cells on either side of the midline dorsally between the somite and the coelom, at the level of somites 8 and 9. The mesonephros arose during day 9 and persisted until day 16. In the male the anterior three tubules were incorporated into the testis at 15.5-16.5 days. The mesonephros consisted of approximately 11 tubules located between somites 10-17. The tubules possessed lumina and connected with the Wolffian duct. Indications of internal and external glomeruli were noted on day 11. The Wolffian duct reached the cloaca at ten days.Strong alkaline phosphatase activity was noted in the differentiating tubules. Cytoplasmic and luminal enzyme activity was observed between 9.3 and 12.5 days indicating possible function at this time. Acid phosphatase was demonstrable in the tubules and duct only on day 11. Ribonucleic acid was observed in the nuclei and cytoplasm of the mesodermal cells as they differentiated into tubules and duct. A decrease in RNA was noted after differentiation was complete. Periodic acid-Schiff material (diastase-stable) was localized in the basement membrane of the tubule and duct cells. A faint positive reaction was also found at the luminal border of the tubules. The strongest reaction was noted in the luminal border at 11.5-12.5 days. Those tubules being incorporated into the genital system in the male were also PAS positive. Morphological and histochemical evidence suggested that the mouse mesonephros, though quasi vestigial, may function for a short time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051200203
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  • 9
    Electronic Resource
    Electronic Resource
    Macralstonin (1966)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 49 (1966), S. 946-964 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Das aus Alstonia macrophylla Wall. (A pocynaceae) isolierte «dimere» Indolalkaloid Macralstonin lässt sich durch verdünnte Salzsäure in die Villalstonin-Spaltbase Macrolin (8) und das ebenfalls aus Alstonia macrophylla isolierte Alkaloid Alstophyllin (2) spalten. Daraus und auf Grund spektroskopischer Untersuchungen (UV.-, IR.-, NMR.-, Massenspektren) wird für Macralstonin die Struktur 1 abgeleitet.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19660490216
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  • 10
    Electronic Resource
    Electronic Resource
    Über die Chemie des Vitamins E 7. Mitteilung [1] die stereospezifische Cyclisierung von (3′R, 7′R, 11′R)-α-TocopherolchinonAuszugsweise vorgetragen an der Winterversammlung der Schweizerischen Chemischen Gesellschaft in Basel am 19.2.1966 (vgl. [2]). (1967)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 50 (1967), S. 1168-1178 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Stereospecific cyclizations of (3′R, 7′R, 11′R)-α-tocopherolquinone (2) are reported:Treatment with conc. sulfuric acid in methanol at 0-5° gave (2R, 4′R, 8′R)-α-tocopherol (1a) with complete retention of configuration at C-3′.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19670500424
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