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  • 1980-1984  (4)
  • 1975-1979  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Health visiting and pre-school children with behavioural problems in the County of South Glamorgan: an exploratory study (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Child 8 (1982), S. 0 
    Details
    ISSN: 1365-2214
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Summary This study surveys firstly, using a modified semantic differential technique, how a sample of health visitors in the County of South Glamorgan perceived different behavioural problems in preschool children. A selection of visiting records, covering a 1-year period, is also studied. Results from the semantic-differential indicate that health visitors perceive eating and sleeping as the most common problem areas. Hyperactivity and sleeping problems are seen as being the most difficult to deal with and the most disruptive to family life. Although health visitors generally feel it is necessary to follow up children with behaviour problems, they find these difficult to resolve. About one third of children are referred to other agencies. Visiting records reveal that children with hyperactivity and sleeping problems receive the highest number of visits from health visitors and that there is little improvement in these children over a period of 1 year. An extension of the health visitor's role and training to include behavioural treatments for pre-school children is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2214.1982.tb00272.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Near IR surface brightness of southern galactic plane (1979)
    [s.l.] : Nature Publishing Group
    Nature 279 (1979), S. 510-512 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The instrument we used is similar to that described by Ito et al.2. Incident radiation was focused by a ??-cm, Fl.O silicon lens onto 1 1 PbS detectors, with fields of view of 0.5, 0.8 and 1.7 at 2.4 p?, and 2.0 at 3.4 ??. The whole telescope system was cooled by liquid nitrogen to reduce the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/279510a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The analysis of lymphoid subpopulations in normal and malignant tissues by immunofluorescence technique (1981)
    Springer
    Journal of cancer research and clinical oncology 101 (1981), S. 1-11 
    Details
    ISSN: 1432-1335
    Keywords: Non-Hodgkin's lymphomas ; Monoclonal antibodies ; Immunofluorescence technique
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Tissue sections of frozen biopsy specimens obtained from normal and hyperplastic human lymphoid tissues as well as 40 cases of non-Hodgkin's lymphomas were analysed in immunofluorescence tests (using red TRITC and green FITC double-labelling). A panel of antisera including well-characterized conventional reagents to immunoglobulin classes, T-lymphoid and Ia-like antigens and monoclonal antibodies, including the OKT range made by Ortho Laboratories, was used. The findings show that the immunological methods can give a very accurate analysis of the normal and malignant lymphoid cells and can provide complementary information to conventional histology. Furthermore, the monoclonal antibodies to well defined lymphocyte subsets can provide data which suggests (although does not prove) functional relationships between different types of cells in normal and malignant lymph nodes. Thus, the technology described fills the gap between conventional histology and cellular immunology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00405058
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Dephosphorylation of glycogen synthase in rat heart extracts by E. coli alkaline phosphatase (1982)
    Springer
    Molecular and cellular biochemistry 44 (1982), S. 149-1591 
    Details
    ISSN: 1573-4919
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary Regulation of the dephosphorylation of glycogen synthase in extracts from rat heart has been studied by adding exogenous phosphatase to the extract. These experiments were possible only because the endogenous protein phosphatase activity of the extract could be inhibited by KF under conditions where alkaline phosphatase activity was not. The concentration of substrate (glycogen synthase from the heart extract) and catalyst (purified E. coli alkaline phosphatase) could be varied independently, by adding known amounts of alkaline phosphatase to the KF-containing heart extracts. Alkaline phosphatase could completely dephosphorylate glycogen synthase while phosphorylase was unchanged. The rate of dephosphorylation was proportional to both the concentration of alkaline phosphatase added to the tissue extract and the amount of glycogen synthase in the extract. The Km for glycogen synthase was close to the concentration found in heart tissue. The Km and the maximum rate of dephosphorylation were both dependent on the phosphorylation state of the glycogen synthase. Less phosphorylated enzyme forms were dephosphorylated faster. These results indicate the necessity for precise control of many variables in studying the rate of glycogen synthase dephosphorylation. Alkaline phosphatase-catalyzed dephosphorylation could be inhibited by physiological concentrations of glycogen. Glycogen synthase dephosphorylation in extracts from fasted-refed rats was less sensitive to glycogen inhibition than in extracts from normal animals. The phosphorylation state of the glycogen synthase in these animals was assessed by kinetic studies to show that differences in phosphorylation state probably could not account for the observations. Fasting led to a decreased rate of dephosphorylation of glycogen synthase due to both an apparent change in kinetic properties of glycogen synthase as a substrate for alkaline phosphatase, and an increased inhibitory effect of glycogen. Stable modifications of glycogen synthase caused by altered nutritional states in the animals are thought to produce these effects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238503
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  • 5
    Electronic Resource
    Electronic Resource
    Immunological and histochemical analysis of regional variations of epidermal Langerhans cells in normal human skin (1984)
    Springer
    Journal of molecular histology 16 (1984), S. 507-519 
    Details
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Epidermal Langerhans' cells (LC) were enumerated in normal human skin from various anatomical sites using a monoclonal antibody (NA1/34) to human thymocyte antigen (HTA-1) and the standard ATPase reaction on frozen sections. The same population of cells was identified with each technique. LC densities were found to be significantly higher in hair bearing skin than in skin from the palm and sole. LC were also identified in hair follicles (where the numbers decreased from the superficial to the deep portions) and sebaceous glands but in no other adnexal structure. Normal numbers were encountered in patients who had received radiotherapy or systemic chemotherapy for malignant disease for periods of greater than two months before death. As LC are important antigen presenting cells, the variation in their density suggests that the immunological properties of normal skin may not be uniform throughout the body. This may be related to the varying anatomical distribution of some skin disorders with an immunological basis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01041351
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    Paper (German National Licenses)
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