ISSN:
1432-0703
Source:
Springer Online Journal Archives 1860-2000
Topics:
Energy, Environment Protection, Nuclear Power Engineering
,
Medicine
Notes:
Abstract A fraction containing polycyclic aromatic hydrocarbons (PAHs), prepared from an organic extract of airborne particulate matter, was separated into nine subfractions by high pressure liquid chromatography (HPLC). The embryotoxicity of each of these fractions was investigated and analysis for PAHs by capillary gas chromatography-mass spectrometry (GC-MS) was performed. The ninth subfraction, with coronene as its main component, had the strongest toxic effects on chicken embryos per m3 of air. Of the remaining eight subfractions, three had the greatest toxicity: the second fraction with benzofluoranthenes and benzo[e]pyrene as the main components, the fourth fraction having PAH-estimated compounds in small amounts, and the fifth fraction with indeno[l,2,3-cd]pyrene and benzo[ghi]perylene as the main ingredients had the greatest toxicity. These findings indicate PAHs to be responsible for embryotoxicity but their total amounts were not necessarily proportional to it. For further characterization of toxicity, the effects of each PAH and/or quantification of other embryotoxic compounds possibly present in small amounts should be investigated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01066413
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