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  • 1
    Electronic Resource
    Electronic Resource
    Evaluation of a therapeutic strategy for the treatment of acne vulgaris with conventional therapy (1986)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 114 (1986), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Four hundred and twenty patients with moderate to severe acne vulgaris were treated with oral erythromycin and topical benzoyl peroxide to determine the optimum dose regimes. Our results show that the response was significantly less in patients with a greater severity of acne, with truncal acne and in those with a higher sebum excretion rate. There was a significantly better clinical result in patients given ig erythromycin daily than in those given 0.5 g daily (plus topical therapy in both groups). The relapse rate on stopping antibiotics is also significantly less in patients given i g daily and this dosage did not produce any increase in side effects. We suggest that any patient requiring oral antibiotics should initially be given i g daily of erythromycin (or tetracycline) for up to six months, plus topical therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1986.tb02827.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pruritus and atopy in Asians (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 10 (1985), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1985.tb00551.x
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  • 3
    Electronic Resource
    Electronic Resource
    Clinical and immunohistological characterization of cutaneous lesions in chronic lymphocytic leukaemia (1985)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 113 (1985), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Twenty-five patients with immunologically classified B cell chronic lymphocytic leukaemia (CLL) were examined for skin lesions. Six showed evidence of cutaneous involvement, and histological examination of skin biopsies form these patients revealed perivascular lymphocytic infiltration with some diffuse involvement in three. Immunohistological analysis with a range of B and T cell specific monoclonal antibodies revealed that in all cases the infiltrate was predominantly T cell in origin and that epidermotropism in three cases was also associated with T cell components. Six control patients with macroscopically normal skin were also biopsied and these biopsies subjected to the same assessment. All were normal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1985.tb02359.x
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of cyproterone acetate-ethinyl estradiol treatment on the proportions of linoleic and sebaleic acids in various skin surface lipid classes (1986)
    Springer
    Archives of dermatological research 278 (1986), S. 481-485 
    Details
    ISSN: 1432-069X
    Keywords: Cyproterone acetate ; Ethinyl estradiol ; Sebum secretion ; Sebum composition ; Linoleic acid ; Acne
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of high-dose cyproterone acetateethinyl estradiol treatment on rates of sebum secretion and on the proportions of linoleic acid (18∶2Δ9,12) and sebaleic acid (18∶2Δ5,8) in the skin surface lipids of three female acne patients was examined. Changes in rates of sebum secretion were evaluated indirectly by measuring the ratio of wax esters/(cholesterol +cholesterol esters) in the subjects' skin surface lipid. In two of the subjects, this ratio indicated a reduction of sebum secretion rates to the childhood range. Concomitantly, there was an increase in linoleic acid and a decrease in sebaleic acid in all lipid classes. In the third subject, in whom there was only a small reduction in sebum secretion rate, the proportion of linoleic acid in the cholesterol esters more than doubled, but the changes in the other lipid classes were small or nonexistent. The results indicate that the proportions of linoleic acid and sebaleic acid in sebum are influenced by sebum secretion rates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00455168
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  • 5
    Electronic Resource
    Electronic Resource
    Continuous measurement of blood hydration during ultrafiltration using optical methods (1987)
    Springer
    Medical & biological engineering & computing 25 (1987), S. 317-323 
    Details
    ISSN: 1741-0444
    Keywords: Blood hydration ; Blood volume ; Body fluids ; Haemodialysis ; Optical absorption ; Ultrafiltration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract An optical blood hydration monitor for use with extracorporeal haemodialysis circuits is described. Studies in five stable haemodialysis patients demonstrate good correlations between measured blood water, haemoglobin concentration and optical attenuation during ultrafiltration. There are no significant errors introduced as a result of a changing extracorporeal circuit pressure and errors resulting from a changing state of oxygenation of haemoglobin are small. Changes in blood volume effected by ultrafiltration may be deduced if it is assumed that these are due solely to shifts of water into or out of the vascular compartment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02447431
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