In:
FEBS Letters, Wiley, Vol. 211, No. 2 ( 1987-01-26), p. 190-194
Abstract:
Myelin basic protein (MBP) reduces the amount of phosphatase activity produced in the kinase F A ‐mediated activation of the ATP,Mg‐dependent phosphatase. MBP was shown not only to inhibit the activated enzyme, but also to impair the kinase F A ‐mediated activation of the inactive phosphatase. In addition MBP prevents the time‐dependent inactivation of the catalytic subunit by the modulator protein. These observations point to a regulatory role for MBP in the reversible activation of the ATP, Mg‐dependent protein phosphatase by kinase F A .
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(87)81434-5
Language:
English
Publisher:
Wiley
Publication Date:
1987
detail.hit.zdb_id:
1460391-3
SSG:
12
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