In:
The International Journal of Artificial Organs, SAGE Publications, Vol. 9, No. 5 ( 1986-09), p. 327-330
Abstract:
A jaundiced dog model was made by common bile duct-inferior vena cava shunt with a silicon rubber tube. Blood bilirubin levels increased from 0.25 ± 0.16 (SD) mg% to 15 ± 1.4 (SD) mg%. These dog models were treated with a column containing 200 gm of macroreticular resin NK-110 which was linked between the femoral artery and vein. The rate of blood flow through the column was 200 ml/min. It was shown that total bilirubin reduced from 15 ± 1.4 (SD) to 7.4 ± 0.61 (SD), conjugated bilirubin decreased from 6.97 ± 0.63 to 3.5 ± 0.33 (SD) and unconjugated bilirubin from 7.8 ± 2.1 to 4.2 ± 0.4 (SD). There were no significant changes in protein, electrolyte, blood gases and acid base balance. Results show that NK-110 resin has good blood-compatible and adsorption properties.
Type of Medium:
Online Resource
ISSN:
0391-3988
,
1724-6040
DOI:
10.1177/039139888600900513
Language:
English
Publisher:
SAGE Publications
Publication Date:
1986
detail.hit.zdb_id:
1474999-3
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