In:
FEBS Letters, Wiley, Vol. 247, No. 2 ( 1989-04-24), p. 217-220
Abstract:
The recently reported alkynyl esters, propynyl benzoate and propynyl p ‐methoxybenzoate, were found to interact with a variety of serine enzymes. α‐Chymotrypsin was inhibited very rapidly by an equivalent amount of the esters. Trypsin, elastase and pronase were also inhibited by the esters. On the other hand, liver esterase started to hydrolyse the alkynyl esters rapidly, but the enzyme became inhibited during the course of reaction. The inhibited enzymes exhibited slow reactivation which could be considerably enhanced by hydroxylamine.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(89)81338-9
Language:
English
Publisher:
Wiley
Publication Date:
1989
detail.hit.zdb_id:
1460391-3
SSG:
12
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