In:
Vox Sanguinis, Wiley, Vol. 56, No. 4 ( 1989-05), p. 283-287
Abstract:
Abstract. Sib a , a new platelet‐specific alloantigen involved in a case of platelet transfusion refractoriness is reported. The IgG platelet alloantibody was detected in a multiply transfused patient of Japanese extraction (Sib), by the presence of HLA antibodies. After transfusion of HLA‐compatible platelets, the patient suffered from refractoriness. Adsorption studies with pooled lymphocytes showed that the serum contained anti‐platelet activity. Family studies indicate that Sib a is inherited as an autosomal codominant trait and separate from HLA and Bak a . As of this report, segregation from Zw (Pl A ) and Yuk (Pen) antigen systems have not yet been determined. The gene frequency of Sib a in the Japanese population is estimated to be 0.136.
Type of Medium:
Online Resource
ISSN:
0042-9007
,
1423-0410
DOI:
10.1111/vox.1989.56.issue-4
DOI:
10.1111/j.1423-0410.1989.tb02043.x
Language:
English
Publisher:
Wiley
Publication Date:
1989
detail.hit.zdb_id:
1483587-3
detail.hit.zdb_id:
80313-3
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