In:
Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 7, No. 3 ( 1987-06), p. 272-279
Abstract:
Endogenous and exogenous oxygen in the rat brain were quantitatively determined using an autoradiographic technique. The oxygen images of frozen and dried rat brain sections were obtained as 18 F images by using the 16 O ( 3 He,p) 18 F reaction for endogenous 16 O images and the 18 O(p,n) 18 F reaction for endogenous and exogenous 18 O images. These autoradiograms demonstrated the different distribution of oxygen between gray and white matter. These images also allowed differentiation of the individual structures of hippocampal formation, owing to the differing water content of the various structures. Local oxygen contents were quantitatively determined from autoradiograms of brain sections and standard sections with known oxygen contents. The estimated values were 75.6 ± 4.6 wt% in gray matter and 72.2 ± 4.0 wt% in white matter. The systematic error in the present method was estimated to be 4.9%.
Type of Medium:
Online Resource
ISSN:
0271-678X
,
1559-7016
DOI:
10.1038/jcbfm.1987.63
Language:
English
Publisher:
SAGE Publications
Publication Date:
1987
detail.hit.zdb_id:
2039456-1
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