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Evaluation of the central retina and optic nerve function in media opacities (1986)

Foerster, M. H. ; Li, X. X.

Springer

Documenta ophthalmologica 63 (1986), S. 101-106

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ISSN: 1573-2622

Keywords: Flicker ERG ; flicker VECP ; maculopathy ; media opacities ; optic atrophy

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Conventional electroretinogram (ERG) and pattern VECP (or visual evoked cortical potential) are of limited value in estimating visual function in eyes with media opacities. We used a method consisting of flicker ERG and flicker VECP to successfully overcome this limitation. Three of 25 eyes with cataract had a reduced flicker VECP. These 3 patients also had a history of glaucomatous optic nerve damage. Normal flicker VECP was found in some patients with reduced flicker ERG or reduced scotopic and photopic a-wave. Analysis of the results showed that the flicker VECP is independent of the ERG and flicker ERG. Utilizing this method we could rule out maculopathy and optic nerve damage in patients with media opacities as well as recognize optic nerve damage in patients with coexisting maculopathy.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00153017

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A preliminary quantum-chemical study of the mechanisms for the reactions of perchlorofluoroethanes with nucleophiles initiated by chlorophilic attacks (1989)

Huang, M.-B. ; Li, X.-Y.

Chichester : Wiley-Blackwell

Journal of Physical Organic Chemistry 2 (1989), S. 103-109

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ISSN: 0894-3230

Keywords: Organic Chemistry ; Physical Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Physics

Notes: A preliminary theoretical study of the mechanisms for the reactions of the perchlorofluoroethanes CF2ClCCl3 (1), CF2ClCCl2F (2) and CF3CCl3 (3), with nucleophiles has been carried out by the MNDO method, following the experimentally suggested process shown in Scheme 1. The unlikely chlorophilic attack in the first step of Scheme 1 has been shown to be feasible for 1, 2 and 3 by analysis of the MO interactions. The second step has been found to be affected by the anionic hyperconjugation which stabilizes the anions CF2ClCCl2- (4), CF2ClCClF- (5) and CF3CCl2- (6) and would make reactions (2) (the second step) unfeasible in gas phase, but in solution reaction (2) may still easily occur for 4 and 5.

Additional Material: 2 Ill.