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  • 1
    ISSN: 1573-6903
    Keywords: Noradrenaline ; 5-hydroxytryptamine ; oviduct ; uterus ; ovariectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper describes the effects of estradiol and progesterone on the concenirations of noradrenaline and 5-hydroxytryptamine in the Wistar rat oviduct and uterus. The levels of noradrenaline and 5-hydroxytryptamine are higher in the oviduct than in the uterus whereas p-tyrosine and tryptophan are similar in both tissues. Estradiol treatment reduced the oviductal concentration of noradrenaline but not 5-hydroxytryptamine in oviduct, while the concentrations of both noradrenaline and 5-hydroxytryptamine were reduced in uterine horn. The levels of noradrenaline in the oviduct and uterus in rats in estrus were lower than those of diestrous rats. Bilateral ovariectomy produced an increase in uterine noradrenaline and 5-hydroxytryptamine levels. These changes were reversed in the presence of ovarian hormones as indicated by experiments where unilateral ovariectomy was performed. Reserpine administration reduced noradrenaline concentration in both the oviduct and the uterus but did not change oviductal or uterine 5-hydroxytryptamine. These results indicate the existence of noradrenaline within postganglionic sympathetic nerve terminals and suggest that estrogens increase the utilization and the synthesis of noradrenaline in both the oviducts and the uterine horns. With respect to 5-hydroxytryptamine the data support the concept that it is mainly associated with mast cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of optimization theory and applications 50 (1986), S. 421-429 
    ISSN: 1573-2878
    Keywords: Admissible controls ; control domains ; functional differential systems ; maximum principle ; optimal periodic control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract This paper discusses the optimal periodic control problem to minimize the cost function $$J(u) = \int_0^1 {g(t,x(t),u(t))dt} $$ subject to the functional differential system $$dx(t)/dt = f(t,x_t ,u(t)),x_1 = x_0 $$ andu(·) εU ad. The maximum principle as a necessary condition of optimal control is proved under the assumption that Eq. (4) and its adjoint equation (5) both have no nontrivial periodic solution with period of 1. In this paper, the control domainU is an arbitrary set inR m.
    Type of Medium: Electronic Resource
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